Opioid-Induced Immunomodulation: Consequences for the Experimental Coxsackievirus B3-Induced Myocarditis Model

by Kathleen Pappritz, Sophie Van Linthout
Published 2020-10-01

Left ventricle- and skeletal muscle-derived fibroblasts exhibit a differential inflammatory and metabolic responsiveness to interleukin-6

by Isabell Matz, Isabell Matz, Kathleen Pappritz, Kathleen Pappritz, Jochen Springer, Jochen Springer, Sophie Van Linthout, Sophie Van Linthout
Published 2022-07-01

Myeloid-Derived Suppressor Cells Restrain Natural Killer Cell Activity in Acute Coxsackievirus B3-Induced Myocarditis

by Irene Müller, Lisa Janson, Martina Sauter, Kathleen Pappritz, Sophie Van Linthout, Carsten Tschöpe, Karin Klingel
Published 2021-05-01

Impact of Syndecan-2-Selected Mesenchymal Stromal Cells on the Early Onset of Diabetic Cardiomyopathy in Diabetic db/db Mice

by Kathleen Pappritz, Kathleen Pappritz, Kathleen Pappritz, Fengquan Dong, Kapka Miteva, Kapka Miteva, Arpad Kovacs, Muhammad El-Shafeey, Muhammad El-Shafeey, Muhammad El-Shafeey, Muhammad El-Shafeey, Bahtiyar Kerim, Lisa O'Flynn, Stephen Joseph Elliman, Timothy O'Brien, Nazha Hamdani, Nazha Hamdani, Nazha Hamdani, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Sophie Van Linthout, Sophie Van Linthout, Sophie Van Linthout
Published 2021-05-01

Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy

by Kapka Miteva, Kathleen Pappritz, Marzena Sosnowski, Muhammad El-Shafeey, Irene Müller, Fengquan Dong, Konstantinos Savvatis, Jochen Ringe, Carsten Tschöpe, Sophie Van Linthout
Published 2018-02-01

Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis

by Kathleen Pappritz, Jie Lin, Muhammad El‐Shafeey, Henry Fechner, Uwe Kühl, Alessio Alogna, Frank Spillmann, Ahmed Elsanhoury, Rainer Schulz, Carsten Tschöpe, Sophie Van Linthout
Published 2022-04-01

Sex- and age-related differences in the inflammatory properties of cardiac fibroblasts: impact on the cardiosplenic axis and cardiac fibrosis

by Kathleen Pappritz, Kathleen Pappritz, Kathleen Pappritz, Sarah-Lena Puhl, Sarah-Lena Puhl, Isabel Matz, Isabel Matz, Isabel Matz, Erik Brauer, Yi Xuan Shia, Muhammad El-Shafeey, Muhammad El-Shafeey, Muhammad El-Shafeey, Muhammad El-Shafeey, Suzanne E. Koch, Suzanne E. Koch, Kapka Miteva, Kapka Miteva, Christin Mucha, Georg N. Duda, Georg N. Duda, Georg N. Duda, Ansgar Petersen, Ansgar Petersen, Ansgar Petersen, Sabine Steffens, Sabine Steffens, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Sophie Van Linthout, Sophie Van Linthout, Sophie Van Linthout
Published 2023-11-01

Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis

by Carsten Tschöpe, Sophie Van Linthout, Sebastian Jäger, Robert Arndt, Tobias Trippel, Irene Müller, Ahmed Elsanhoury, Susanne Rutschow, Stefan D. Anker, Heinz‐Peter Schultheiss, Matthias Pauschinger, Frank Spillmann, Kathleen Pappritz
Published 2020-10-01

CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis.

by Irene Müller, Kathleen Pappritz, Konstantinos Savvatis, Kerstin Puhl, Fengquan Dong, Muhammad El-Shafeey, Nazha Hamdani, Isabell Hamann, Michel Noutsias, Carmen Infante-Duarte, Wolfgang A Linke, Sophie Van Linthout, Carsten Tschöpe
Published 2017-01-01

Mesenchymal stromal cells but not cardiac fibroblasts exert beneficial systemic immunomodulatory effects in experimental myocarditis.

by Konstantinos Savvatis, Sophie van Linthout, Kapka Miteva, Kathleen Pappritz, Dirk Westermann, Joerg C Schefold, Gerhard Fusch, Alice Weithäuser, Ursula Rauch, Peter-Moritz Becher, Karin Klingel, Jochen Ringe, Andreas Kurtz, Heinz-Peter Schultheiss, Carsten Tschöpe
Published 2012-01-01

Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction

by Jana Grune, Daniel Ritter, Kristin Kräker, Kathleen Pappritz, Niklas Beyhoff, Till Schütte, Christiane Ott, Cathleen John, Sophie van Linthout, Carsten Tschöpe, Ralf Dechend, Dominik N. Muller, Nadine Haase, Tilman Grune, Ulrich Kintscher, Wolfgang M. Kuebler
Published 2019-04-01

Spontaneous Degenerative Aortic Valve Disease in New Zealand Obese Mice

by Christiane Ott, Kathleen Pappritz, Niklas Hegemann, Cathleen John, Sarah Jeuthe, Cameron S. McAlpine, Yoshiko Iwamoto, Jonathan H. Lauryn, Jan Klages, Robert Klopfleisch, Sophie Van Linthout, Fil Swirski, Matthias Nahrendorf, Ulrich Kintscher, Tilman Grune, Wolfgang M. Kuebler, Jana Grune
Published 2021-12-01