Racial differences in RAD51 expression are regulated by miRNA-214-5P and its inhibition synergizes with olaparib in triple-negative breast cancer

by Chinnadurai Mani, Ganesh Acharya, Karunakar Saamarthy, Damieanus Ochola, Srinidhi Mereddy, Kevin Pruitt, Upender Manne, Komaraiah Palle
Published 2023-04-01

CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stress and overcomes chemoresistance in ovarian cancer

by Ganesh Acharya, Chinnadurai Mani, Naresh Sah, Karunakar Saamarthy, Robert Young, Mark B. Reedy, Robert W. Sobol, Komaraiah Palle
Published 2024-06-01

Discovery of a small molecule that inhibits Bcl-3-mediated cyclin D1 expression in melanoma cells

by Karunakar Saamarthy, Kristofer Ahlqvist, Renée Daams, Navisraj Balagunaseelan, Agnes Rinaldo-Matthis, Julhash U. Kazi, Wondossen Sime, Ramin Massoumi
Published 2024-01-01