Interrupting the Conversation: Implications for Crosstalk Between Viral and Bacterial Infections in the Asthmatic Airway

by Jodie Ackland, Alastair Watson, Alastair Watson, Alastair Watson, Tom M. A. Wilkinson, Tom M. A. Wilkinson, Tom M. A. Wilkinson, Karl J. Staples, Karl J. Staples, Karl J. Staples
Published 2021-10-01

Dual RNASeq Reveals NTHi-Macrophage Transcriptomic Changes During Intracellular Persistence

by Jodie Ackland, Ashley I. Heinson, David W. Cleary, David W. Cleary, Myron Christodoulides, Tom M. A. Wilkinson, Tom M. A. Wilkinson, Tom M. A. Wilkinson, Karl J. Staples, Karl J. Staples, Karl J. Staples
Published 2021-08-01

Defining a role for exercise training in the management of asthma

by Anna T. Freeman, Karl J. Staples, Tom M.A. Wilkinson
Published 2020-07-01

Human CD49a+ Lung Natural Killer Cell Cytotoxicity in Response to Influenza A Virus

by Grace E. Cooper, Kristoffer Ostridge, Kristoffer Ostridge, Salim I. Khakoo, Tom M. A. Wilkinson, Tom M. A. Wilkinson, Tom M. A. Wilkinson, Karl J. Staples, Karl J. Staples
Published 2018-07-01

The Role of Non-Typeable Haemophilus influenzae Biofilms in Chronic Obstructive Pulmonary Disease

by Jake R. Weeks, Karl J. Staples, Karl J. Staples, C. Mirella Spalluto, C. Mirella Spalluto, Alastair Watson, Alastair Watson, Alastair Watson, Tom M. A. Wilkinson, Tom M. A. Wilkinson
Published 2021-08-01

Influence of Hypoxia on the Epithelial-Pathogen Interactions in the Lung: Implications for Respiratory Disease

by Lee K. Page, Karl J. Staples, Karl J. Staples, C. Mirella Spalluto, C. Mirella Spalluto, Alastair Watson, Alastair Watson, Alastair Watson, Tom M. A. Wilkinson, Tom M. A. Wilkinson
Published 2021-03-01

The Role of Extracellular Vesicles as a Shared Disease Mechanism Contributing to Multimorbidity in Patients With COPD

by Laura V. Reid, C. Mirella Spalluto, C. Mirella Spalluto, Alastair Watson, Alastair Watson, Alastair Watson, Karl J. Staples, Karl J. Staples, Tom M. A. Wilkinson, Tom M. A. Wilkinson
Published 2021-12-01

Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands.

by Ben Nicholas, Alistair Bailey, Karl J Staples, Tom Wilkinson, Tim Elliott, Paul Skipp
Published 2022-01-01

Mechanisms of Hypoxic Up-Regulation of Versican Gene Expression in Macrophages.

by Fattah Sotoodehnejadnematalahi, Karl J Staples, Elvina Chrysanthou, Helen Pearson, Loems Ziegler-Heitbrock, Bernard Burke
Published 2015-01-01

Development of flow cytometric opsonophagocytosis and antibody-mediated complement deposition assays for non-typeable Haemophilus influenzae

by Stephen R. Thomas, Stephanie Leung, Katy Knox, Tom M. A. Wilkinson, Karl J. Staples, Pascal Lestrate, Dominique Wauters, Andrew Gorringe, Stephen C. Taylor
Published 2018-10-01

EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma.

by Mohib Uddin, Laurie C Lau, Grégory Seumois, Pandurangan Vijayanand, Karl J Staples, Dinesh Bagmane, Victoria Cornelius, Paul Dorinsky, Donna E Davies, Ratko Djukanović
Published 2013-01-01

Pulmonary EV miRNA profiles identify disease and distinct inflammatory endotypes in COPD

by Hannah Burke, Hannah Burke, Doriana Cellura, Doriana Cellura, Anna Freeman, Anna Freeman, Alex Hicks, Alex Hicks, Kris Ostridge, Kris Ostridge, Alastair Watson, Alastair Watson, Nicholas P. Williams, Nicholas P. Williams, C. Mirella Spalluto, C. Mirella Spalluto, Karl J. Staples, Karl J. Staples, Tom M. A. Wilkinson, Tom M. A. Wilkinson
Published 2022-12-01

Viral infection of human lung macrophages increases PDL1 expression via IFNβ.

by Karl J Staples, Ben Nicholas, Richard T McKendry, C Mirella Spalluto, Joshua C Wallington, Craig W Bragg, Emily C Robinson, Kirstin Martin, Ratko Djukanović, Tom M A Wilkinson
Published 2015-01-01

Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD.

by Karl J Staples, Stephen Taylor, Steve Thomas, Stephanie Leung, Karen Cox, Thierry G Pascal, Kristoffer Ostridge, Lindsay Welch, Andrew C Tuck, Stuart C Clarke, Andrew Gorringe, Tom M A Wilkinson
Published 2016-01-01

Correction: Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD.

by Karl J Staples, Stephen Taylor, Steve Thomas, Stephanie Leung, Karen Cox, Thierry G Pascal, Kristoffer Ostridge, Lindsay Welch, Andrew C Tuck, Stuart C Clarke, Andrew Gorringe, Tom M A Wilkinson
Published 2017-01-01

Patient perceived barriers to exercise and their clinical associations in difficult asthma

by Anna T. Freeman, David Hill, Colin Newell, Helen Moyses, Adnan Azim, Deborah Knight, Laura Presland, Matthew Harvey, Hans Michael Haitchi, Alastair Watson, Karl J. Staples, Ramesh J. Kurukulaaratchy, Tom M. A. Wilkinson
Published 2020-06-01

Viral Inhibition of Bacterial Phagocytosis by Human Macrophages: Redundant Role of CD36.

by Grace E Cooper, Zoe C Pounce, Joshua C Wallington, Leidy Y Bastidas-Legarda, Ben Nicholas, Chiamaka Chidomere, Emily C Robinson, Kirstin Martin, Anna S Tocheva, Myron Christodoulides, Ratko Djukanovic, Tom M A Wilkinson, Karl J Staples
Published 2016-01-01

Exercise Training Induces a Shift in Extracellular Redox Status with Alterations in the Pulmonary and Systemic Redox Landscape in Asthma

by Anna Freeman, Doriana Cellura, Magdalena Minnion, Bernadette O. Fernandez, Cosma Mirella Spalluto, Denny Levett, Andrew Bates, Timothy Wallis, Alastair Watson, Sandy Jack, Karl J. Staples, Michael P. W. Grocott, Martin Feelisch, Tom M. A. Wilkinson
Published 2021-11-01

Dysregulation of COVID-19 related gene expression in the COPD lung

by Alastair Watson, Lisa Öberg, Bastian Angermann, C. Mirella Spalluto, Michael Hühn, Hannah Burke, Doriana Cellura, Anna Freeman, Daniel Muthas, Damla Etal, Graham Belfield, Fredrik Karlsson, Karl Nordström, Kris Ostridge, Karl J. Staples, Tom Wilkinson, the MICA II Studygroup
Published 2021-05-01

Relationship of CT-quantified emphysema, small airways disease and bronchial wall dimensions with physiological, inflammatory and infective measures in COPD

by Kristoffer Ostridge, Nicholas P. Williams, Viktoriya Kim, Stephen Harden, Simon Bourne, Stuart C. Clarke, Emmanuel Aris, Sonia Mesia-Vela, Jeanne-Marie Devaster, Andrew Tuck, Anthony Williams, Stephen Wootton, Karl J. Staples, Tom M. A. Wilkinson, on behalf of the AERIS Study Group
Published 2018-02-01