Siponimod exerts neuroprotective effects on the retina and higher visual pathway through neuronal S1PR1 in experimental glaucoma

by Devaraj Basavarajappa, Vivek Gupta, Nitin Chitranshi, Roshana Vander Wall, Rashi Rajput, Kanishka Pushpitha, Samridhi Sharma, Mehdi Mirzaei, Alexander Klistorner, Stuart L Graham
Published 2023-01-01

Evolving geographic diversity in SARS-CoV2 and in silico analysis of replicating enzyme 3CLpro targeting repurposed drug candidates

by Nitin Chitranshi, Vivek K. Gupta, Rashi Rajput, Angela Godinez, Kanishka Pushpitha, Ting Shen, Mehdi Mirzaei, Yuyi You, Devaraj Basavarajappa, Veer Gupta, Stuart L. Graham
Published 2020-07-01

Amyloid-beta peptide neurotoxicity in human neuronal cells is associated with modulation of insulin-like growth factor transport, lysosomal machinery and extracellular matrix recep...

by Liting Deng, Paul A Haynes, Yunqi Wu, Ardeshir Amirkhani, Karthik Shantharam Kamath, Jemma X Wu, Kanishka Pushpitha, Veer Gupta, Stuart Graham, Vivek K Gupta, Mehdi Mirzaei
Published 2020-01-01

Oxidative Stress Induced Dysfunction of Protein Synthesis in 661W Mice Photoreceptor Cells

by Liting Deng, Vivek Gupta, Morteza Abyadeh, Nitin Chitranshi, Kanishka Pushpitha, Yunqi Wu, Veer Gupta, Yuyi You, Joao A. Paulo, Stuart L. Graham, Mehdi Mirzaei, Paul A. Haynes
Published 2023-04-01

Tau modulation through AAV9 therapy augments Akt/Erk survival signalling in glaucoma mitigating the retinal degenerative phenotype

by Kanishka Pushpitha Maha Thananthirige, Nitin Chitranshi, Devaraj Basavarajappa, Rashi Rajput, Mojdeh Abbasi, Viswanthram Palanivel, Veer Bala Gupta, Joao A. Paulo, Maya Koronyo-Hamaoui, Mehdi Mirzaei, Stuart L. Graham, Vivek Gupta
Published 2024-06-01

Amyloid β Induces Early Changes in the Ribosomal Machinery, Cytoskeletal Organization and Oxidative Phosphorylation in Retinal Photoreceptor Cells

by Liting Deng, Kanishka Pushpitha, Chitra Joseph, Veer Gupta, Rashi Rajput, Nitin Chitranshi, Yogita Dheer, Ardeshir Amirkhani, Ardeshir Amirkhani, Karthik Kamath, Karthik Kamath, Dana Pascovici, Dana Pascovici, Jemma X. Wu, Jemma X. Wu, Ghasem Hosseini Salekdeh, Ghasem Hosseini Salekdeh, Paul A. Haynes, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Mehdi Mirzaei, Mehdi Mirzaei
Published 2019-02-01