Amino acid–insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells

by Kalaitzidis, Demetrios, Lee, Dongjun, Efeyan, Alejo, Kfoury, Youmna Sami, Nayyar, Naema, Sykes, David Brian, Mercier, Francois, Papazian, Ani Elizabeth, Baryawno, Ninib, Victora, Gabriel D., Neuberg, Donna S., Sabatini, David Alexander, Scadden, David Thomas
Published 2018

Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors

by Lee, Dongjun, Sykes, Stephen M., Kalaitzidis, Demetrios, Lane, Andrew A., Kfoury, Youmna, Raaijmakers, Marc H.G.P., Wang, Ying-Hua, Armstrong, Scott A., Scadden, David T.
Published 2014

Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy

by Lee, Dongjun, Wang, Ying-Hua, Kalaitzidis, Demetrios, Ramachandran, Janani, Eda, Homare, Sykes, David Brian, Raje, Noopur, Scadden, David Thomas
Published 2018

Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome–associated PTPN11 mutation

by Marin, Talita M., Keith, Kimberly, Davies, Benjamin Ivor, Conner, David Atwater, Guha, Prajna, Kalaitzidis, Demetrios, Wu, Xue, Lauriol, Jessica, Wang, Bo, Bauer, Michael, Bronson, Roderick Terry, Franchini, Kleber G., Neel, Benjamin G., Kontaridis, Maria Irene
Published 2017