Enhanced anti-tumor effect of zoledronic acid combined with temozolomide against human malignant glioma cell expressing O6-methylguanine DNA methyltransferase.

by Junya Fukai, Fumiaki Koizumi, Naoyuki Nakao
Published 2014-01-01

Survival prediction based on the gene expression associated with cancer morphology and microenvironment in primary central nervous system lymphoma.

by Yasuo Takashima, Atsushi Kawaguchi, Junya Fukai, Yasuo Iwadate, Koji Kajiwara, Hiroaki Hondoh, Ryuya Yamanaka
Published 2021-01-01

Ruptured Internal Carotid Artery Aneurysm Presenting with Catastrophic Epistaxis after Repeated Stereotactic Radiotherapies for Anterior Skull Base Tumor: Case Reports and Review o...

by Koji Fujita, Manabu Tamura, Osamu Masuo, Takahiro Sasaki, Toshikazu Yamoto, Junya Fukai, Naoyuki Nakao
Published 2014-08-01

miR-101, miR-548b, miR-554, and miR-1202 are reliable prognosis predictors of the miRNAs associated with cancer immunity in primary central nervous system lymphoma.

by Yasuo Takashima, Atsushi Kawaguchi, Yasuo Iwadate, Hiroaki Hondoh, Junya Fukai, Koji Kajiwara, Azusa Hayano, Ryuya Yamanaka
Published 2020-01-01

MicroRNA signature constituted of miR-30d, miR-93, and miR-181b is a promising prognostic marker in primary central nervous system lymphoma.

by Yasuo Takashima, Atsushi Kawaguchi, Yasuo Iwadate, Hiroaki Hondoh, Junya Fukai, Koji Kajiwara, Azusa Hayano, Ryuya Yamanaka
Published 2019-01-01

Prognostic Factors and Histopathological Features of Pediatric Intracranial Ependymomas: Nationwide Brain Tumor Registry-based Study of Japan

by Takahiro SASAKI, Yuji UEMATSU, Junya FUKAI, Shota TANAKA, Akitake MUKASA, Nobuhito SAITO, Yoshitaka NARITA, Naoyuki NAKAO
Published 2022-07-01

Differential expression of individual transcript variants of PD-1 and PD-L2 genes on Th-1/Th-2 status is guaranteed for prognosis prediction in PCNSL

by Yasuo Takashima, Atsushi Kawaguchi, Ryuichi Sato, Kenichi Yoshida, Azusa Hayano, Jumpei Homma, Junya Fukai, Yasuo Iwadate, Koji Kajiwara, Shin Ishizawa, Hiroaki Hondoh, Masakazu Nakano, Seishi Ogawa, Kei Tashiro, Ryuya Yamanaka
Published 2019-07-01

Impact of Inversion Time for FLAIR Acquisition on the T2-FLAIR Mismatch Detectability for IDH-Mutant, Non-CODEL Astrocytomas

by Manabu Kinoshita, Hideyuki Arita, Hideyuki Arita, Masamichi Takahashi, Takehiro Uda, Junya Fukai, Kenichi Ishibashi, Noriyuki Kijima, Ryuichi Hirayama, Mio Sakai, Atsuko Arisawa, Hiroto Takahashi, Katsuyuki Nakanishi, Naoki Kagawa, Kouichi Ichimura, Yonehiro Kanemura, Yoshitaka Narita, Haruhiko Kishima
Published 2021-01-01

Distribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohorts

by Toru Umehara, Hideyuki Arita, Ema Yoshioka, Tomoko Shofuda, Daisuke Kanematsu, Manabu Kinoshita, Yoshinori Kodama, Masayuki Mano, Naoki Kagawa, Yasunori Fujimoto, Yoshiko Okita, Masahiro Nonaka, Kosuke Nakajo, Takehiro Uda, Naohiro Tsuyuguchi, Junya Fukai, Koji Fujita, Daisuke Sakamoto, Kanji Mori, Haruhiko Kishima, Yonehiro Kanemura
Published 2019-06-01

Activated leukocyte cell adhesion molecule expression correlates with the WNT subgroup in medulloblastoma and is involved in regulating tumor cell proliferation and invasion.

by Takamune Achiha, Noriyuki Kijima, Yoshinori Kodama, Naoki Kagawa, Manabu Kinoshita, Yasunori Fujimoto, Masahiro Nonaka, Junya Fukai, Akihiro Inoue, Namiko Nishida, Takumi Yamanaka, Atsuko Harada, Kanji Mori, Naohiro Tsuyuguchi, Takehiro Uda, Kenichi Ishibashi, Yusuke Tomogane, Daisuke Sakamoto, Tomoko Shofuda, Ema Yoshioka, Daisuke Kanematsu, Masayuki Mano, Betty Luu, Michael D Taylor, Yonehiro Kanemura, Haruhiko Kishima
Published 2020-01-01

A common deletion at BAK1 reduces enhancer activity and confers risk of intracranial germ cell tumors

by Kyuto Sonehara, Yui Kimura, Yoshiko Nakano, Tatsuya Ozawa, Meiko Takahashi, Ken Suzuki, Takashi Fujii, Yuko Matsushita, Arata Tomiyama, Toshihiro Kishikawa, Kenichi Yamamoto, Tatsuhiko Naito, Tomonari Suzuki, Shigeru Yamaguchi, Tomoru Miwa, Hikaru Sasaki, Masashi Kitagawa, Naoyuki Ohe, Junya Fukai, Hideki Ogiwara, Atsufumi Kawamura, Satoru Miyawaki, Fumihiko Matsuda, Nobutaka Kiyokawa, Koichi Ichimura, Ryo Nishikawa, Yukinori Okada, Keita Terashima
Published 2022-08-01

Fine-Tuning Approach for Segmentation of Gliomas in Brain Magnetic Resonance Images with a Machine Learning Method to Normalize Image Differences among Facilities

by Satoshi Takahashi, Masamichi Takahashi, Manabu Kinoshita, Mototaka Miyake, Risa Kawaguchi, Naoki Shinojima, Akitake Mukasa, Kuniaki Saito, Motoo Nagane, Ryohei Otani, Fumi Higuchi, Shota Tanaka, Nobuhiro Hata, Kaoru Tamura, Kensuke Tateishi, Ryo Nishikawa, Hideyuki Arita, Masahiro Nonaka, Takehiro Uda, Junya Fukai, Yoshiko Okita, Naohiro Tsuyuguchi, Yonehiro Kanemura, Kazuma Kobayashi, Jun Sese, Koichi Ichimura, Yoshitaka Narita, Ryuji Hamamoto
Published 2021-03-01

Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors

by Kohei Fukuoka, Yonehiro Kanemura, Tomoko Shofuda, Shintaro Fukushima, Satoshi Yamashita, Daichi Narushima, Mamoru Kato, Mai Honda-Kitahara, Hitoshi Ichikawa, Takashi Kohno, Atsushi Sasaki, Junko Hirato, Takanori Hirose, Takashi Komori, Kaishi Satomi, Akihiko Yoshida, Kai Yamasaki, Yoshiko Nakano, Ai Takada, Taishi Nakamura, Hirokazu Takami, Yuko Matsushita, Tomonari Suzuki, Hideo Nakamura, Keishi Makino, Yukihiko Sonoda, Ryuta Saito, Teiji Tominaga, Yasuhiro Matsusaka, Keiichi Kobayashi, Motoo Nagane, Takuya Furuta, Mitsutoshi Nakada, Yoshitaka Narita, Yuichi Hirose, Shigeo Ohba, Akira Wada, Katsuyoshi Shimizu, Kazuhiko Kurozumi, Isao Date, Junya Fukai, Yousuke Miyairi, Naoki Kagawa, Atsufumi Kawamura, Makiko Yoshida, Namiko Nishida, Takafumi Wataya, Masayoshi Yamaoka, Naohiro Tsuyuguchi, Takehiro Uda, Mayu Takahashi, Yoshiteru Nakano, Takuya Akai, Shuichi Izumoto, Masahiro Nonaka, Kazuhisa Yoshifuji, Yoshinori Kodama, Masayuki Mano, Tatsuya Ozawa, Vijay Ramaswamy, Michael D. Taylor, Toshikazu Ushijima, Soichiro Shibui, Mami Yamasaki, Hajime Arai, Hiroaki Sakamoto, Ryo Nishikawa, Koichi Ichimura, on behalf of the Japan Pediatric Molecular Neuro-Oncology Group (JPMNG)
Published 2018-12-01