Vasa Vasorum Angiogenesis: Key Player in the Initiation and Progression of Atherosclerosis and Potential Target for the Treatment of Cardiovascular Disease

by Daniel G. Sedding, Erin C. Boyle, Jasper A. F. Demandt, Judith C. Sluimer, Judith C. Sluimer, Jochen Dutzmann, Axel Haverich, Johann Bauersachs
Published 2018-04-01

Single-cell transcriptomics reveals subtype-specific molecular profiles in Nrf2-deficient macrophages from murine atherosclerotic aortas

by Katarzyna Sarad, Katarzyna Sarad, Monika Stefańska, Izabela Kraszewska, Krzysztof Szade, Judith C. Sluimer, Judith C. Sluimer, Przemysław Błyszczuk, Przemysław Błyszczuk, Józef Dulak, Agnieszka Jaźwa-Kusior
Published 2023-10-01

Culture density influences the functional phenotype of human macrophages

by Adele V. Ruder, Lieve Temmerman, Joep M.A. van Dommelen, Jan Nagenborg, Chang Lu, Judith C. Sluimer, Judith C. Sluimer, Pieter Goossens, Erik A.L. Biessen, Erik A.L. Biessen
Published 2023-03-01

Targeting Non-coding RNA in Vascular Biology and Disease

by John Hung, John Hung, Vladislav Miscianinov, Judith C. Sluimer, David E. Newby, Andrew H. Baker
Published 2018-11-01

Whole-Body Prolyl Hydroxylase Domain (PHD) 3 Deficiency Increased Plasma Lipids and Hematocrit Without Impacting Plaque Size in Low-Density Lipoprotein Receptor Knockout Mice

by Jasper A. F. Demandt, Kim van Kuijk, Kim van Kuijk, Thomas L. Theelen, Elke Marsch, Sean P. Heffron, Edward A. Fisher, Peter Carmeliet, Peter Carmeliet, Erik A. L. Biessen, Erik A. L. Biessen, Judith C. Sluimer, Judith C. Sluimer
Published 2021-05-01

Iron Oxide Nanoparticle Uptake in Mouse Brachiocephalic Artery Atherosclerotic Plaque Quantified by T₂-Mapping MRI

by Rik P. M. Moonen, Bram F. Coolen, Judith C. Sluimer, Mat J. A. P. Daemen, Gustav J. Strijkers
Published 2021-02-01

Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice

by Laura Parma, Hendrika A. B. Peters, Fabiana Baganha, Judith C. Sluimer, Margreet R. de Vries, Paul H.A. Quax
Published 2020-02-01

Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis

by Renée J. H. A. Tillie, Jenny De Bruijn, Javier Perales-Patón, Javier Perales-Patón, Lieve Temmerman, Yanal Ghosheh, Kim Van Kuijk, Marion J. Gijbels, Marion J. Gijbels, Marion J. Gijbels, Peter Carmeliet, Peter Carmeliet, Peter Carmeliet, Klaus Ley, Klaus Ley, Julio Saez-Rodriguez, Julio Saez-Rodriguez, Judith C. Sluimer, Judith C. Sluimer
Published 2021-08-01

A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis

by Renée J. H. A. Tillie, Thomas L. Theelen, Kim van Kuijk, Lieve Temmerman, Jenny de Bruijn, Marion Gijbels, Christer Betsholtz, Erik A. L. Biessen, Judith C. Sluimer
Published 2021-07-01

Identification of a gene network driving the attenuated response to lipopolysaccharide of monocytes from hypertensive coronary artery disease patients

by Chang Lu, Chang Lu, Marjo M. P. C. Donners, Julius B. J. de Baaij, Han Jin, Han Jin, Jeroen J. T. Otten, Marco Manca, Anton Jan van Zonneveld, J. Wouter Jukema, J. Wouter Jukema, Adriaan Kraaijeveld, Johan Kuiper, Gerard Pasterkamp, Barend Mees, Judith C. Sluimer, Judith C. Sluimer, Rachel Cavill, Joël M. H. Karel, Pieter Goossens, Erik A. L. Biessen, Erik A. L. Biessen
Published 2024-02-01

Heart rate lowering treatment leads to a reduction in vulnerable plaque features in atherosclerotic rabbits.

by Raf H M van Hoof, Evelien Hermeling, Judith C Sluimer, Julie Salzmann, Arnold P G Hoeks, Jérôme Roussel, Mat J A P Daemen, Harry Struijker-Boudier, Joachim E Wildberger, Sylvia Heeneman, M Eline Kooi
Published 2017-01-01

Myeloid PHD2 Conditional Knockout Improves Intraplaque Angiogenesis and Vascular Remodeling in a Murine Model of Venous Bypass Grafting

by Thijs J. Sluiter, Renée J. H. A. Tillie, Alwin de Jong, Jenny B. G. de Bruijn, Hendrika A. B. Peters, Remco van de Leijgraaf, Raghed Halawani, Michelle Westmaas, Lineke I. W. Starink, Paul H. A. Quax, Judith C. Sluimer, Margreet R. de Vries
Published 2024-02-01

Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome

by Johanna P. van Geffen, Frauke Swieringa, Kim van Kuijk, Bibian M. E. Tullemans, Fiorella A. Solari, Bing Peng, Kenneth J. Clemetson, Richard W. Farndale, Ludwig J. Dubois, Albert Sickmann, René P. Zahedi, Robert Ahrends, Erik A. L. Biessen, Judith C. Sluimer, Johan W. M. Heemskerk, Marijke J. E. Kuijpers
Published 2020-12-01

Integrative multiomics analysis of human atherosclerosis reveals a serum response factor‐driven network associated with intraplaque hemorrhage

by Han Jin, Pieter Goossens, Peter Juhasz, Wouter Eijgelaar, Marco Manca, Joël M. H. Karel, Evgueni Smirnov, Cornelis J. J. M. Sikkink, Barend M. E. Mees, Olivia Waring, Kim van Kuijk, Gregorio E. Fazzi, Marion J. J. Gijbels, Martina Kutmon, Chris T. A. Evelo, Ulf Hedin, Mat J. A. P. Daemen, Judith C. Sluimer, Ljubica Matic, Erik A. L. Biessen
Published 2021-06-01

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

by Jeroen Baardman, Sanne G. S. Verberk, Saskia van der Velden, Marion J. J. Gijbels, Cindy P. P. A. van Roomen, Judith C. Sluimer, Jelle Y. Broos, Guillermo R. Griffith, Koen H. M. Prange, Michel van Weeghel, Soufyan Lakbir, Douwe Molenaar, Elisa Meinster, Annette E. Neele, Gijs Kooij, Helga E. de Vries, Esther Lutgens, Kathryn E. Wellen, Menno P. J. de Winther, Jan Van den Bossche
Published 2020-12-01