MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC

by Kaiqiang Zhao, Mingyue Zheng, Zezhuo Su, Shrestha Ghosh, Chao Zhang, Wenzhao Zhong, Joshua Wing Kei Ho, Guoxiang Jin, Zhongjun Zhou
Published 2023-08-01

An artificial intelligence-enabled smartphone app for real-time pressure injury assessment

by Chun Hon Lau, Chun Hon Lau, Ken Hung-On Yu, Ken Hung-On Yu, Tsz Fung Yip, Tsz Fung Yip, Luke Yik Fung Luk, Luke Yik Fung Luk, Abraham Ka Chung Wai, Tin-Yan Sit, Janet Yuen-Ha Wong, Janet Yuen-Ha Wong, Joshua Wing Kei Ho, Joshua Wing Kei Ho
Published 2022-09-01

Multi-Level Biomarkers for Early Diagnosis of Ischaemic Stroke: A Systematic Review and Meta-Analysis

by Qianyun Li, Lingyun Zhao, Ching Long Chan, Yilin Zhang, See Wai Tong, Xiaodan Zhang, Joshua Wing Kei Ho, Yaqing Jiao, Timothy Hudson Rainer
Published 2023-09-01

Deficiency of exchange protein directly activated by cAMP (EPAC)-1 in mice augments glucose intolerance, inflammation, and gut dysbiosis associated with Western diet

by Preeti Dinesh Virwani, Lin Cai, Patrick Ka Kit Yeung, Gordon Qian, Yingxian Chen, Lei Zhou, Jason Wing Hon Wong, Yu Wang, Joshua Wing Kei Ho, Kui Kai Lau, Pei-Yuan Qian, Sookja Kim Chung
Published 2022-11-01

A single-cell atlas of conventional central chondrosarcoma reveals the role of endoplasmic reticulum stress in malignant transformation

by Zezhuo Su, Joshua Wing Kei Ho, Raymond Ching Hing Yau, Ying Lee Lam, Tony Wai Hung Shek, Maximus Chun Fai Yeung, Hongtai Chen, Richard O. C. Oreffo, Kathryn Song Eng Cheah, Kelvin Sin Chi Cheung
Published 2024-01-01

Using Genomics Feature Selection Method in Radiomics Pipeline Improves Prognostication Performance in Locally Advanced Esophageal Squamous Cell Carcinoma—A Pilot Study

by Chen-Yi Xie, Yi-Huai Hu, Joshua Wing-Kei Ho, Lu-Jun Han, Hong Yang, Jing Wen, Ka-On Lam, Ian Yu-Hong Wong, Simon Ying-Kit Law, Keith Wan-Hang Chiu, Jian-Hua Fu, Varut Vardhanabhuti
Published 2021-04-01

Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson’s Disease

by Meng Cai, Meng Cai, Songshan Chai, Tao Xiong, Jun Wei, Weibing Mao, Yasha Zhu, Xiang Li, Wei Wei, Xuan Dai, Bangkun Yang, Wen Liu, Bing Shu, Mengyang Wang, Taojunjin Lu, Yuankun Cai, Zhixin Zheng, Zhimin Mei, Yixuan Zhou, Jingyi Yang, Jingwei Zhao, Lei Shen, Joshua Wing Kei Ho, Jincao Chen, Nanxiang Xiong
Published 2021-08-01

Association of Molnupiravir and Nirmatrelvir-Ritonavir with preventable mortality, hospital admissions and related avoidable healthcare system cost among high-risk patients with mi...

by Abraham Ka-Chung Wai, Crystal Ying Chan, Annie Wai-Ling Cheung, Kailu Wang, Sunny Ching-Long Chan, Teddy Tai-Loy Lee, Luke Yik-Fung Luk, Edmond Tsz-Fung Yip, Joshua Wing-Kei Ho, Omar Wai-Kiu Tsui, Kelly Wing-Yin Cheung, Shiyeow Lee, Chak-kwan Tong, Tafu Yamamoto, Timothy Hudson Rainer, Eliza Lai-Yi Wong
Published 2023-01-01

Association of Molnupiravir and Nirmatrelvir-Ritonavir with reduced mortality and sepsis in hospitalized omicron patients: a territory-wide study

by Abraham Ka-chung Wai, Teddy Tai-loy Lee, Sunny Ching-long Chan, Crystal Ying Chan, Edmond Tsz-fung Yip, Luke Yik-fung Luk, Joshua Wing-kei Ho, Kevin Wang-leong So, Omar Wai-kiu Tsui, Man-lok Lam, Shi-yeow Lee, Tafu Yamamoto, Chak-kwan Tong, Man-sing Wong, Eliza Lai-yi Wong, Timothy Hudson Rainer
Published 2023-05-01