Heritability and circulating concentrations of pregnancy-associated plasma protein-A and stanniocalcin-2 in elderly monozygotic and dizygotic twins

by Rikke Hjortebjerg, Rikke Hjortebjerg, Rikke Hjortebjerg, Dorthe Almind Pedersen, Jonas Mengel-From, Jonas Mengel-From, Louise Helskov Jørgensen, Kaare Christensen, Kaare Christensen, Jan Frystyk, Jan Frystyk
Published 2023-06-01

CLU genetic variants and cognitive decline among elderly and oldest old.

by Jonas Mengel-From, Mikael Thinggaard, Rune Lindahl-Jacobsen, Matt McGue, Kaare Christensen, Lene Christiansen
Published 2013-01-01

Familial Risk and Heritability of Hematologic Malignancies in the Nordic Twin Study of Cancer

by Signe B. Clemmensen, Jennifer R. Harris, Jonas Mengel-From, Wagner H. Bonat, Henrik Frederiksen, Jaakko Kaprio, Jacob v. B. Hjelmborg
Published 2021-06-01

Skewness of X-chromosome inactivation increases with age and varies across birth cohorts in elderly Danish women

by Jonas Mengel-From, Rune Lindahl-Jacobsen, Marianne Nygaard, Mette Soerensen, Karen Helene Ørstavik, Jens Michael Hertz, Karen Andersen-Ranberg, Qihua Tan, Kaare Christensen
Published 2021-02-01

A Mass Spectrometry-Based Proteome Study of Twin Pairs Discordant for Incident Acute Myocardial Infarction within Three Years after Blood Sampling Suggests Novel Biomarkers

by Hans Christian Beck, Asmus Cosmos Skovgaard, Afsaneh Mohammadnejad, Nicolai Bjødstrup Palstrøm, Palle Fruekilde Nielsen, Jonas Mengel-From, Jacob Hjelmborg, Lars Melholt Rasmussen, Mette Soerensen
Published 2024-02-01

Global Gene Expression Profiling and Transcription Factor Network Analysis of Cognitive Aging in Monozygotic Twins

by Afsaneh Mohammadnejad, Weilong Li, Weilong Li, Jesper Beltoft Lund, Jesper Beltoft Lund, Shuxia Li, Martin J. Larsen, Martin J. Larsen, Jonas Mengel-From, Jonas Mengel-From, Tanja Maria Michel, Tanja Maria Michel, Tanja Maria Michel, Lene Christiansen, Lene Christiansen, Kaare Christensen, Kaare Christensen, Jacob Hjelmborg, Jan Baumbach, Jan Baumbach, Qihua Tan, Qihua Tan
Published 2021-06-01

Genome-Wide Epistatic Network Analyses of Semantic Fluency in Older Adults

by Qihua Tan, Weilong Li, Marianne Nygaard, Ping An, Mary Feitosa, Mary K. Wojczynski, Joseph Zmuda, Konstantin Arbeev, Svetlana Ukraintseva, Anatoliy Yashin, Kaare Christensen, Jonas Mengel-From
Published 2024-05-01

Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohortsResearch in context

by Juulia Jylhävä, Jacob Hjelmborg, Mette Soerensen, Elizabeth Munoz, Qihua Tan, Ralf Kuja-Halkola, Jonas Mengel-From, Kaare Christensen, Lene Christiansen, Sara Hägg, Nancy L. Pedersen, Chandra A. Reynolds
Published 2019-02-01

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

by Shuxia Li, Jesper B. Lund, Kaare Christensen, Jan Baumbach, Jonas Mengel-From, Torben Kruse, Weilong Li, Afsaneh Mohammadnejad, Alison Pattie, Riccardo E. Marioni, Ian J. Deary, Qihua Tan
Published 2020-04-01

Toll-like receptor 4 methylation grade is linked to depressive symptom severity

by Annica J. Rasmusson, Maike Gallwitz, Bardia Soltanabadi, Diana M. Ciuculete, Jonas Mengel-From, Kaare Christensen, Marianne Nygaard, Mette Soerensen, Adrian E. Boström, Robert Fredriksson, Eva Freyhult, Jessica Mwinyi, Darina Czamara, Elisabeth B. Binder, Helgi B. Schiöth, Janet L. Cunningham
Published 2021-06-01

Long-Lived Individuals Show a Lower Burden of Variants Predisposing to Age-Related Diseases and a Higher Polygenic Longevity Score

by Guillermo G. Torres, Janina Dose, Tim P. Hasenbein, Marianne Nygaard, Ben Krause-Kyora, Jonas Mengel-From, Kaare Christensen, Karen Andersen-Ranberg, Daniel Kolbe, Wolfgang Lieb, Matthias Laudes, Siegfried Görg, Stefan Schreiber, Andre Franke, Amke Caliebe, Gregor Kuhlenbäumer, Almut Nebel
Published 2022-09-01

A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants

by Harold Bae, Anastasia Gurinovich, Tanya T. Karagiannis, Zeyuan Song, Anastasia Leshchyk, Mengze Li, Stacy L. Andersen, Konstantin Arbeev, Anatoliy Yashin, Joseph Zmuda, Ping An, Mary Feitosa, Cristina Giuliani, Claudio Franceschi, Paolo Garagnani, Jonas Mengel-From, Gil Atzmon, Nir Barzilai, Annibale Puca, Nicholas J. Schork, Thomas T. Perls, Paola Sebastiani
Published 2022-12-01

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

by Daniel L. McCartney, Josine L. Min, Rebecca C. Richmond, Ake T. Lu, Maria K. Sobczyk, Gail Davies, Linda Broer, Xiuqing Guo, Ayoung Jeong, Jeesun Jung, Silva Kasela, Seyma Katrinli, Pei-Lun Kuo, Pamela R. Matias-Garcia, Pashupati P. Mishra, Marianne Nygaard, Teemu Palviainen, Amit Patki, Laura M. Raffield, Scott M. Ratliff, Tom G. Richardson, Oliver Robinson, Mette Soerensen, Dianjianyi Sun, Pei-Chien Tsai, Matthijs D. van der Zee, Rosie M. Walker, Xiaochuan Wang, Yunzhang Wang, Rui Xia, Zongli Xu, Jie Yao, Wei Zhao, Adolfo Correa, Eric Boerwinkle, Pierre-Antoine Dugué, Peter Durda, Hannah R. Elliott, Christian Gieger, The Genetics of DNA Methylation Consortium, Eco J. C. de Geus, Sarah E. Harris, Gibran Hemani, Medea Imboden, Mika Kähönen, Sharon L. R. Kardia, Jacob K. Kresovich, Shengxu Li, Kathryn L. Lunetta, Massimo Mangino, Dan Mason, Andrew M. McIntosh, Jonas Mengel-From, Ann Zenobia Moore, Joanne M. Murabito, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Miina Ollikainen, James S. Pankow, Nancy L. Pedersen, Annette Peters, Silvia Polidoro, David J. Porteous, Olli Raitakari, Stephen S. Rich, Dale P. Sandler, Elina Sillanpää, Alicia K. Smith, Melissa C. Southey, Konstantin Strauch, Hemant Tiwari, Toshiko Tanaka, Therese Tillin, Andre G. Uitterlinden, David J. Van Den Berg, Jenny van Dongen, James G. Wilson, John Wright, Idil Yet, Donna Arnett, Stefania Bandinelli, Jordana T. Bell, Alexandra M. Binder, Dorret I. Boomsma, Wei Chen, Kaare Christensen, Karen N. Conneely, Paul Elliott, Luigi Ferrucci, Myriam Fornage, Sara Hägg, Caroline Hayward, Marguerite Irvin, Jaakko Kaprio, Deborah A. Lawlor, Terho Lehtimäki, Falk W. Lohoff, Lili Milani, Roger L. Milne, Nicole Probst-Hensch, Alex P. Reiner, Beate Ritz, Jerome I. Rotter, Jennifer A. Smith, Jack A. Taylor, Joyce B. J. van Meurs, Paolo Vineis, Melanie Waldenberger, Ian J. Deary, Caroline L. Relton, Steve Horvath, Riccardo E. Marioni
Published 2021-06-01