The Classical Complement Pathway Is Required to Control Borrelia burgdorferi Levels During Experimental Infection

by Hui Zhi, Jialei Xie, Jon T. Skare
Published 2018-05-01

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex.

by Brandon L Garcia, Hui Zhi, Beau Wager, Magnus Höök, Jon T Skare
Published 2016-01-01

Borrelia miyamotoi FbpA and FbpB Are Immunomodulatory Outer Surface Lipoproteins With Distinct Structures and Functions

by Charles E. Booth, Alexandra D. Powell-Pierce, Jon T. Skare, Brandon L. Garcia
Published 2022-05-01

Structural determination of the complement inhibitory domain of Borrelia burgdorferi BBK32 provides insight into classical pathway complement evasion by Lyme disease spirochetes.

by Jialei Xie, Hui Zhi, Ryan J Garrigues, Andrew Keightley, Brandon L Garcia, Jon T Skare
Published 2019-03-01

The intergenic small non-coding RNA ittA is required for optimal infectivity and tissue tropism in Borrelia burgdorferi.

by Diana N Medina-Pérez, Beau Wager, Erin Troy, Lihui Gao, Steven J Norris, Tao Lin, Linden Hu, Jenny A Hyde, Meghan Lybecker, Jon T Skare
Published 2020-05-01

Genome-wide screen identifies novel genes required for Borrelia burgdorferi survival in its Ixodes tick vector.

by James P Phelan, Aurelie Kern, Meghan E Ramsey, Maureen E Lundt, Bijaya Sharma, Tao Lin, Lihui Gao, Steven J Norris, Jenny A Hyde, Jon T Skare, Linden T Hu
Published 2019-05-01

Biomechanics of Borrelia burgdorferi Vascular Interactions

by Rhodaba Ebady, Alexandra F. Niddam, Anna E. Boczula, Yae Ram Kim, Nupur Gupta, Tian Tian Tang, Tanya Odisho, Hui Zhi, Craig A. Simmons, Jon T. Skare, Tara J. Moriarty
Published 2016-09-01

A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species.

by Meghan E Ramsey, Jenny A Hyde, Diana N Medina-Perez, Tao Lin, Tao Lin, Lihui Gao, Maureen E Lundt, Xin Li, Steven J Norris, Jon T Skare, Linden T Hu
Published 2017-02-01