Lipotoxic Injury Differentially Regulates Brain Microvascular Gene Expression in Male Mice

by Saivageethi Nuthikattu, Dragan Milenkovic, John C. Rutledge, Amparo C. Villablanca
Published 2020-06-01

Sex-Dependent Molecular Mechanisms of Lipotoxic Injury in Brain Microvasculature: Implications for Dementia

by Saivageethi Nuthikattu, Dragan Milenkovic, John C. Rutledge, Amparo C. Villablanca
Published 2020-10-01

C-terminal interactions of apolipoprotein E4 respond to the postprandial state

by Sarada D. Tetali, Madhu S. Budamagunta, John C. Voss, John C. Rutledge
Published 2006-07-01

17β-Estradiol reduces tumor necrosis factor-α-mediated LDL accumulation in the artery wall

by Barbara A. Walsh, Adam E. Mullick, Rosemary L. Walzem, John C. Rutledge
Published 1999-03-01

17β-Estradiol acts separately on the LDL particle and artery wall to reduce LDL accumulation

by Barbara A. Walsh, Adam E. Mullick, Carole E. Banka, John C. Rutledge
Published 2000-01-01

Sex-Specific Response of the Brain Free Oxylipin Profile to Soluble Epoxide Hydrolase Inhibition

by Jennifer E. Norman, Saivageethi Nuthikattu, Dragan Milenkovic, John C. Rutledge, Amparo C. Villablanca
Published 2023-02-01

Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation

by Limin Wang, Rajan Gill, Theresa L. Pedersen, Laura J. Higgins, John W. Newman, John C. Rutledge
Published 2009-02-01

Angiotensin II increases vascular proteoglycan content preceding and contributing to atherosclerosis development1

by Fei Huang, Joel C. Thompson, Patricia G. Wilson, Hnin H. Aung, John C. Rutledge, Lisa R. Tannock
Published 2008-03-01

TGRL Lipolysis Products Induce Stress Protein ATF3 via the TGF-β Receptor Pathway in Human Aortic Endothelial Cells.

by Larissa Eiselein, Tun Nyunt, Michael W Lamé, Kit F Ng, Dennis W Wilson, John C Rutledge, Hnin H Aung
Published 2015-01-01

Lipotoxic brain microvascular injury is mediated by activating transcription factor 3-dependent inflammatory and oxidative stress pathways

by Hnin Hnin Aung, Robin Altman, Tun Nyunt, Jeffrey Kim, Saivageethi Nuthikattu, Madhu Budamagunta, John C. Voss, Dennis Wilson, John C. Rutledge, Amparo C. Villablanca
Published 2016-06-01

Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation.

by Laura J den Hartigh, Robin Altman, Romobia Hutchinson, Jitka Petrlova, Madhu S Budamagunta, Sarada D Tetali, Jens O Lagerstedt, John C Voss, John C Rutledge
Published 2012-01-01

Interaction between mild hypercholesterolemia, HDL-cholesterol levels, and angiotensin II in intimal hyperplasia in mice

by Valdeci da Cunha, Baby Martin-McNulty, Jon Vincelette, Lening Zhang, John C. Rutledge, Dennis W. Wilson, Ronald Vergona, Mark E. Sullivan, Yi-Xin Wang
Published 2006-03-01

VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation

by Sarada D. Tetali, Madhu S. Budamagunta, Catalina Simion, Laura J. den Hartigh, Tamás Kálai, Kálmán Hideg, Danny M. Hatters, Karl H. Weisgraber, John C. Voss, John C. Rutledge
Published 2010-06-01

High‐Intensity Statin Therapy Is Associated With Improved Survival in Patients With Peripheral Artery Disease

by T. Raymond Foley, Gagan D. Singh, Damianos G. Kokkinidis, Ho‐Hin K. Choy, Tai H. Pham, Ezra A. Amsterdam, John C. Rutledge, Stephen W. Waldo, Ehrin J. Armstrong, John R. Laird
Published 2017-07-01

Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet.

by Jennifer M Rutkowsky, Linda L Lee, Michelle Puchowicz, Mari S Golub, Douglas E Befroy, Dennis W Wilson, Steven Anderson, Gary Cline, Jason Bini, Kamil Borkowski, Trina A Knotts, John C Rutledge, Mouse Metabolic Phenotyping Center Imaging Working Group
Published 2018-01-01