Reactive oxygen species overload promotes apoptosis in JAK2V617F-positive cell lines

by João Agostinho Machado-Neto, Fabiola Traina

Exploring redox vulnerabilities in JAK2V617F-positive cellular models

by Keli Lima, Lucia Rossetti Lopes, João Agostinho Machado-Neto
Published 2021-10-01

Perspectives for Targeting Ezrin in Cancer Development and Progression

by Jean Carlos Lipreri da Silva, Hugo Passos Vicari, João Agostinho Machado-Neto
Published 2023-01-01

Cellular and Molecular Effects of Eribulin in Preclinical Models of Hematologic Neoplasms

by Hugo Passos Vicari, Keli Lima, Leticia Veras Costa-Lotufo, João Agostinho Machado-Neto
Published 2022-12-01

Stathmin 1 expression in plasma cell neoplasms

by João Agostinho Machado-Neto, Fernando Vieira Pericole, Fernando Ferreira Costa, Fabiola Traina, Sara Teresinha Olalla Saad

NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells

by Lívia Bassani Lins de Miranda, Keli Lima, Juan Luiz Coelho-Silva, Fabiola Traina, Susumu S. Kobayashi, João Agostinho Machado-Neto
Published 2022-10-01

Differential profile of CDKN1A and TP53 expressions in bone marrow mesenchymal stromal cells from myeloid neoplasms

by Matheus Rodrigues Lopes, João Agostinho Machado-Neto, Fabiola Traina, Paula de Melo Campos, Sara Teresinha Olalla Saad, Patricia Favaro

PTK2 and PTPN11 expression in myelodysplastic syndromes

by Mariana Lazarini, Joao Agostinho Machado-Neto, Leticia Frohlich Archangelo, Bruna Fernandes Mendes-Silva, Carolina Louzao Bigarella, Fabiola Traina, Sara Teresinha Olalla Saad
Published 2013-10-01

Seriniquinones as Therapeutic Leads for Treatment of BRAF and NRAS Mutant Melanomas

by Amanda S. Hirata, Paula Rezende-Teixeira, João Agostinho Machado-Neto, Paula C. Jimenez, James J. La Clair, William Fenical, Leticia V. Costa-Lotufo
Published 2021-12-01

ARHGAP6 transcript levels are associated with molecular risk and impact survival outcomes in acute myeloid leukemia

by Jean Carlos Lipreri da Silva, Juan Luiz Coelho-Silva, Hugo Passos Vicari, Keli Lima, Eduardo Magalhães Rego, Fabiola Traina, João Agostinho Machado-Neto
Published 2024-01-01

Clinical and molecular profile of a Brazilian cohort of patients with classical BCR-ABL1-negative myeloproliferative neoplasms

by Moysés Antonio Porto-Soares, Rafael Daltro de Oliveira, Gabriel Macedo Cortopassi, João Agostinho Machado-Neto, Leonardo Carvalho Palma, Lorena Lobo de Figueiredo-Pontes
Published 2020-07-01

Two-Dimensional and Spheroid-Based Three-Dimensional Cell Culture Systems: Implications for Drug Discovery in Cancer

by Anali del Milagro Bernabe Garnique, Natália Sudan Parducci, Lívia Bassani Lins de Miranda, Bruna Oliveira de Almeida, Leonardo Sanches, João Agostinho Machado-Neto
Published 2024-06-01

P347: PHARMACOLOGICAL EZRIN INHIBITION REDUCES GROWTH, ADHESION, MIGRATION AND REGULATE GENE RELATED TO APOPTOSIS AND CELL CYCLE IN ACUTE LYMPHOBLASTIC LEUKAEMIA

by Jean Carlos Lipreri Da Silva, Keli Lima, Mariana Lazarini, Hugo Passos Vicari, Eduardo Magalhães Rego, Benjamin Ede, Anne Ridley, João Agostinho Machado Neto
Published 2023-08-01

Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis

by João Agostinho Machado-Neto, Bruna Alves Fenerich, Ana Paula Nunes Rodrigues Alves, Jaqueline Cristina Fernandes, Renata Scopim-Ribeiro, Juan Luiz Coelho-Silva, Fabiola Traina
Published 2018-10-01

Somatic mutations of calreticulin in a Brazilian cohort of patients with myeloproliferative neoplasms

by João Agostinho Machado-Neto, Paula de Melo Campos, Dulcinéia Martins de Albuquerque, Fernando Ferreira Costa, Irene Lorand-Metze, Sara Terezinha Olalla Saad, Fabiola Traina
Published 2015-06-01

Screening for hotspot mutations in PI3K, JAK2, FLT3 and NPM1 in patients with myelodysplastic syndromes

by João Agostinho Machado-Neto, Fabiola Traina, Mariana Lazarini, Paula de Melo Campos, Katia Borgia Barbosa Pagnano, Irene Lorand-Metze, Fernando Ferreira Costa, Sara T Olalla Saad
Published 2011-01-01

Comprehensive analysis of the HCK gene in myeloid neoplasms: Insights into biological functions, prognosis, and response to antineoplastic agents

by Maria Fernanda Lopes Carvalho, Bruna Oliveira de Almeida, Maura Lima Pereira Bueno, Hugo Passos Vicari, Keli Lima, Eduardo Magalhães Rego, Fernanda Marconi Roversi, João Agostinho Machado-Neto
Published 2024-07-01

BNIP3L in myelodysplastic syndromes and acute myeloid leukemia: impact on disease outcome and cellular response to decitabine

by Mariana Lazarini, João Agostinho Machado-Neto, Adriana da Silva Santos Duarte, Fernando Vieira Pericole, Karla Priscila Vieira, Fernanda S. Niemann, Marisa Alvarez, Fabiola Traina, Sara Teresinha Olalla Saad
Published 2016-11-01

Obatoclax reduces cell viability of acute myeloid leukemia cell lines independently of their sensitivity to venetoclax

by Keli Lima, Hugo Passos Vicari, Jorge Antonio Elias Godoy Carlos, Jean Carlos Lipreri da Silva, Lorena Lobo de Figueiredo-Pontes, Eduardo Magalhães Rego, João Agostinho Machado-Neto
Published 2022-01-01

PB1826: CELLULAR AND MOLECULAR CHARACTERIZATION OF THE ANTINEOPLASTIC EFFECTS OF CEPHALOCHROMIN IN MODELS OF ACUTE MYELOID LEUKEMIA

by Mariane Cristina Do Nascimento, Diego A Pereira-Martins, Guilherme Augusto Sousa Alcântara, Keli Lima, Hugo Passos Vicari, Marcelo José Pena Ferreira, Leticia Leticia Veras Costa-Lotufo, João Agostinho Machado Neto, Eduardo Magalhães Rego
Published 2023-08-01