MYC predetermines the sensitivity of gastrointestinal cancer to antifolate drugs through regulating TYMS transcription

by Tingting Liu, Yumin Han, Chunhong Yu, Yan Ji, Changxu Wang, Xiaomin Chen, Xiang Wang, Jiayan Shen, Yongfeng Zhang, Jing-Yu Lang
Published 2019-10-01

Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex

by Xiang Wang, Qing Xie, Yan Ji, Jiaxin Yang, Jiayan Shen, Fangfei Peng, Yongfeng Zhang, Feng Jiang, Xiangyin Kong, Wenzhe Ma, Dandan Liu, Leizhen Zheng, Chen Qing, Jing-Yu Lang
Published 2023-01-01

Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance

by Li‐Min Wang, Pingyuan Wang, Xiao‐Min Chen, Hui Yang, Shan‐Shan Song, Zilan Song, Li Jia, Hua‐Dong Chen, Xu‐Bin Bao, Ne Guo, Xia‐Juan Huan, Yong Xi, Yan‐Yan Shen, Xin‐Ying Yang, Yi Su, Yi‐Ming Sun, Ying‐Lei Gao, Yi Chen, Jian Ding, Jing‐Yu Lang, Ze‐Hong Miao, Ao Zhang, Jin‐Xue He
Published 2023-03-01