The Utility of Amino Acid Metabolites in the Diagnosis of Major Depressive Disorder and Correlations with Depression Severity

by Cyrus Su Hui Ho, Gabrielle Wann Nii Tay, Hai Ning Wee, Jianhong Ching
Published 2023-01-01

Dried Blood Spots as Matrix for Evaluation of Valproate Levels and the Immediate and Delayed Metabolomic Changes Induced by Single Valproate Dose Treatment

by Sing Teang Kong, Hai-Shu Lin, Jianhong Ching, Huiqing Xie, Paul C. Ho
Published 2022-06-01

Lipidomics Workflow for Analyzing Lipid Profiles Using Multiple Reaction Monitoring (MRM) in Liver Homogenate of Mice with Non-alcoholic Steatohepatitis (NASH)

by Hai Ning Wee, Lye Siang Lee, Sharon Han, Jin Zhou, Paul Yen, Jianhong Ching
Published 2023-07-01

Characteristics of pulmonary artery strain assessed by cardiovascular magnetic resonance imaging and associations with metabolomic pathways in human ageing

by Hongzhou Zhang, Hongzhou Zhang, Shuang Leng, Shuang Leng, Fei Gao, Fei Gao, Jean-Paul Kovalik, Jean-Paul Kovalik, Hai Ning Wee, Kee Voon Chua, Jianhong Ching, Jianhong Ching, John C. Allen, Xiaodan Zhao, Ru-San Tan, Ru-San Tan, Qinghua Wu, Tim Leiner, Angela S. Koh, Angela S. Koh, Liang Zhong, Liang Zhong
Published 2024-02-01

Integration of the Cortical Haemodynamic Response Measured by Functional Near-Infrared Spectroscopy and Amino Acid Analysis to Aid in the Diagnosis of Major Depressive Disorder

by Samantha K. Ong, Syeda F. Husain, Hai Ning Wee, Jianhong Ching, Jean-Paul Kovalik, Man Si Cheng, Herbert Schwarz, Tong Boon Tang, Cyrus S. Ho
Published 2021-10-01

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

by Kyung Cheul Shin, Injae Hwang, Sung Sik Choe, Jeu Park, Yul Ji, Jong In Kim, Gha Young Lee, Sung Hee Choi, Jianhong Ching, Jean-Paul Kovalik, Jae Bum Kim
Published 2017-10-01

Profiling of Plasma Metabolites Suggests Altered Mitochondrial Fuel Usage and Remodeling of Sphingolipid Metabolism in Individuals With Type 2 Diabetes and Kidney Disease

by Jian-Jun Liu, Sujoy Ghosh, Jean-Paul Kovalik, Jianhong Ching, Hyung Won Choi, Subramaniam Tavintharan, Choon Nam Ong, Chee Fang Sum, Scott A. Summers, E. Shyong Tai, Su Chi Lim
Published 2017-05-01

Effects of short-term moderate intensity exercise on the serum metabolome in older adults: a pilot randomized controlled trial

by Jie Jun Wong, Jien Sze Ho, Louis L. Y. Teo, Hai Ning Wee, Kee Voon Chua, Jianhong Ching, Fei Gao, Swee Yaw Tan, Ru-San Tan, Jean-Paul Kovalik, Angela S. Koh
Published 2024-05-01

Metabolic stress is a primary pathogenic event in transgenic Caenorhabditis elegans expressing pan-neuronal human amyloid beta

by Emelyne Teo, Sudharshan Ravi, Diogo Barardo, Hyung-Seok Kim, Sheng Fong, Amaury Cazenave-Gassiot, Tsze Yin Tan, Jianhong Ching, Jean-Paul Kovalik, Markus R Wenk, Rudiyanto Gunawan, Philip K Moore, Barry Halliwell, Nicholas Tolwinski, Jan Gruber
Published 2019-10-01

Beyond fitness tracking: The use of consumer-grade wearable data from normal volunteers in cardiovascular and lipidomics research.

by Weng Khong Lim, Sonia Davila, Jing Xian Teo, Chengxi Yang, Chee Jian Pua, Christopher Blöcker, Jing Quan Lim, Jianhong Ching, Jonathan Jiunn Liang Yap, Swee Yaw Tan, Anders Sahlén, Calvin Woon-Loong Chin, Bin Tean Teh, Steven G Rozen, Stuart Alexander Cook, Khung Keong Yeo, Patrick Tan
Published 2018-02-01

Fasting increases susceptibility to acute myocardial ischaemia/reperfusion injury through a sirtuin-3 mediated increase in fatty acid oxidation

by Andrew R. Hall, Qutuba G. Karwi, Sanjeev Kumar, Rachel Dongworth, Dunja Aksentijević, Tariq R. Altamimi, Kevin Timothy Fridianto, Kroekkiat Chinda, Sauri Hernandez-Resendiz, Mohammad U. Mahmood, Evangelos Michelakis, Chrishan J. Ramachandra, Jianhong Ching, Jose M. Vicencio, Michael J. Shattock, Jean-Paul Kovalik, Derek M. Yellon, Gary Lopaschuk, Derek J. Hausenloy
Published 2022-11-01

Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in Acute Myocardial Infarction

by Leonardo P. de Carvalho, MD, PhD, Sock Hwee Tan, PhD, Ghim-Siong Ow, BSc, Zhiqun Tang, PhD, Jianhong Ching, PhD, Jean-Paul Kovalik, MD, PhD, Sock Cheng Poh, BSc, Chee-Tang Chin, MBBS, A. Mark Richards, MD, PhD, Eliana C. Martinez, MD, PhD, Richard W. Troughton, MD, PhD, Alan Yean-Yip Fong, MBBS, Bryan P. Yan, MBBS, Aruni Seneviratna, MBBS, MPH, Vitaly Sorokin, MD, PhD, Scott A. Summers, PhD, Vladimir A. Kuznetsov, PhD, SciD, Mark Y. Chan, MBBS, PhD
Published 2018-04-01

Multi-omics tools for studying microbial biofilms: current perspectives and future directions

by Chaminda Jayampath Seneviratne, Tanujaa suriyanarayanan, Armelia Widyarman, Lye Siang Lee, Wen Jian Matthew Lau, Jianhong Ching, Christopher Delaney, Gordon Ramage
Published 2020