An Impact-Echo Experimental Approach for Detecting Concrete Structural Faults

by Ya-xun Yang, Wen-hao Chai, De-chuang Liu, Wei-de Zhang, Jia-cheng Lu, Zhi-kui Yang
Published 2021-01-01

Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma

by Peng-Fei Zhang, Chao Gao, Xiao-Yong Huang, Jia-Cheng Lu, Xiao-Jun Guo, Guo-Ming Shi, Jia-Bin Cai, Ai-Wu Ke
Published 2020-06-01

Current applications and future perspective of CRISPR/Cas9 gene editing in cancer

by Si-Wei Wang, Chao Gao, Yi-Min Zheng, Li Yi, Jia-Cheng Lu, Xiao-Yong Huang, Jia-Bin Cai, Peng-Fei Zhang, Yue-Hong Cui, Ai-Wu Ke
Published 2022-02-01

Correction: Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis

by Xiao-Yong Huang, Peng-Fei Zhang, Chuan-Yuan Wei, Rui Peng, Jia-Cheng Lu, Chao Gao, Jia-Bing Cai, Xuan Yang, Jia Fan, Ai-Wu Ke, Jian Zhou, Guo-Ming Shi
Published 2024-02-01

Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis

by Xiao-Yong Huang, Peng-Fei Zhang, Chuan-Yuan Wei, Rui Peng, Jia-Cheng Lu, Chao Gao, Jia-Bing Cai, Xuan Yang, Jia Fan, Ai-Wu Ke, Jian Zhou, Guo-Ming Shi
Published 2020-05-01

Downregulation of RNF128 activates Wnt/β-catenin signaling to induce cellular EMT and stemness via CD44 and CTTN ubiquitination in melanoma

by Chuan-Yuan Wei, Meng-Xuan Zhu, Yan-Wen Yang, Peng-Fei Zhang, Xuan Yang, Rui Peng, Chao Gao, Jia-Cheng Lu, Lu Wang, Xin-Yi Deng, Nan-Hang Lu, Fa-Zhi Qi, Jian-Ying Gu
Published 2019-03-01

KSR2-14–3-3ζ complex serves as a biomarker and potential therapeutic target in sorafenib-resistant hepatocellular carcinoma

by Chao Gao, Si-wei Wang, Jia-cheng Lu, Xiao-qiang Chai, Yuan-cheng Li, Peng-fei Zhang, Xiao-yong Huang, Jia-bin Cai, Yi-min Zheng, Xiao-jun Guo, Guo-ming Shi, Ai-wu Ke, Jia Fan
Published 2022-04-01

Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression

by Peng-Fei Zhang, Chuan-Yuan Wei, Xiao-Yong Huang, Rui Peng, Xuan Yang, Jia-Cheng Lu, Chi Zhang, Chao Gao, Jia-Bin Cai, Ping-Ting Gao, Dong-Mei Gao, Guo-Ming Shi, Ai-Wu Ke, Jia Fan
Published 2019-06-01

Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma

by Rui Peng, Peng-Fei Zhang, Xuan Yang, Chuan-Yuan Wei, Xiao-Yong Huang, Jia-Bin Cai, Jia-Cheng Lu, Chao Gao, Hai-Xiang Sun, Qiang Gao, Dou-Sheng Bai, Guo-Ming Shi, Ai-Wu Ke, Jia Fan
Published 2019-03-01

Amplification of spatially isolated adenosine pathway by tumor–macrophage interaction induces anti-PD1 resistance in hepatocellular carcinoma

by Jia-Cheng Lu, Peng-Fei Zhang, Xiao-Yong Huang, Xiao-Jun Guo, Chao Gao, Hai-Ying Zeng, Yi-Min Zheng, Si-Wei Wang, Jia-Bin Cai, Qi-Man Sun, Ying-Hong Shi, Jian Zhou, Ai-Wu Ke, Guo-Ming Shi, Jia Fan
Published 2021-11-01

CTLA-4 Synergizes With PD1/PD-L1 in the Inhibitory Tumor Microenvironment of Intrahepatic Cholangiocarcinoma

by Xiao-Jun Guo, Xiao-Jun Guo, Xiao-Jun Guo, Jia-Cheng Lu, Jia-Cheng Lu, Jia-Cheng Lu, Hai-Ying Zeng, Rong Zhou, Qi-Man Sun, Qi-Man Sun, Qi-Man Sun, Guo-Huan Yang, Guo-Huan Yang, Guo-Huan Yang, Yan-Zi Pei, Yan-Zi Pei, Yan-Zi Pei, Xian-Long Meng, Xian-Long Meng, Xian-Long Meng, Ying-Hao Shen, Ying-Hao Shen, Ying-Hao Shen, Peng-Fei Zhang, Peng-Fei Zhang, Peng-Fei Zhang, Jia-Bin Cai, Jia-Bin Cai, Jia-Bin Cai, Pei-Xin Huang, Ai-Wu Ke, Ai-Wu Ke, Ying-Hong Shi, Ying-Hong Shi, Ying-Hong Shi, Jian Zhou, Jian Zhou, Jian Zhou, Jia Fan, Jia Fan, Jia Fan, Yi Chen, Liu-Xiao Yang, Guo-Ming Shi, Guo-Ming Shi, Guo-Ming Shi, Xiao-Yong Huang, Xiao-Yong Huang, Xiao-Yong Huang
Published 2021-08-01

Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis

by Xiao-Jun Guo, Xiao-Yong Huang, Xuan Yang, Jia-Cheng Lu, Chuan-Yuan Wei, Chao Gao, Yan-Zi Pei, Yi Chen, Qi-Man Sun, Jia-Bin Cai, Jian Zhou, Jia Fan, Ai-Wu Ke, Yujiang G. Shi, Ying-Hao Shen, Peng-Fei Zhang, Guo-Ming Shi, Guo-Huan Yang
Published 2023-02-01

Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: a single-center, single-arm, phase 2 stu...

by Guo-Ming Shi, Xiao-Yong Huang, Dong Wu, Hui-Chuan Sun, Fei Liang, Yuan Ji, Yi Chen, Guo-Huan Yang, Jia-Cheng Lu, Xian-Long Meng, Xin-Ying Wang, Lei Sun, Ning-Ling Ge, Xiao-Wu Huang, Shuang-Jian Qiu, Xin-Rong Yang, Qiang Gao, Yi-Feng He, Yang Xu, Jian Sun, Zheng-Gang Ren, Jia Fan, Jian Zhou
Published 2023-03-01

Macro CD5L+ deteriorates CD8+T cells exhaustion and impairs combination of Gemcitabine-Oxaliplatin-Lenvatinib-anti-PD1 therapy in intrahepatic cholangiocarcinoma

by Jia-Cheng Lu, Lei-Lei Wu, Yi-Ning Sun, Xiao-Yong Huang, Chao Gao, Xiao-Jun Guo, Hai-Ying Zeng, Xu-Dong Qu, Yi Chen, Dong Wu, Yan-Zi Pei, Xian-Long Meng, Yi-Min Zheng, Chen Liang, Peng-Fei Zhang, Jia-Bin Cai, Zhen-Bin Ding, Guo-Huan Yang, Ning Ren, Cheng Huang, Xiao-Ying Wang, Qiang Gao, Qi-Man Sun, Ying-Hong Shi, Shuang-Jian Qiu, Ai-Wu Ke, Guo-Ming Shi, Jian Zhou, Yi-Di Sun, Jia Fan
Published 2024-01-01