Super-resolution imaging and quantification of megakaryocytes and platelets

by Abdullah O. Khan, Jeremy A. Pike
Published 2020-07-01

CRISPR-Cas9 Mediated Labelling Allows for Single Molecule Imaging and Resolution

by Abdullah O. Khan, Victoria A. Simms, Jeremy A. Pike, Steven G. Thomas, Neil V. Morgan
Published 2017-08-01

Immobilized collagen prevents shedding and induces sustained GPVI clustering and signaling in platelets

by Chiara Pallini, Jeremy A. Pike, Christopher O’Shea, Robert K. Andrews, Elizabeth E. Gardiner, Steve P. Watson, Natalie S. Poulter
Published 2021-01-01

An adaptable analysis workflow for characterization of platelet spreading and morphology

by Jeremy A. Pike, Victoria A. Simms, Christopher W. Smith, Neil V. Morgan, Abdullah O. Khan, Natalie S. Poulter, Iain B. Styles, Steven G. Thomas
Published 2021-01-01

Platelet glycoprotein VI and C-type lectin-like receptor 2 deficiency accelerates wound healing by impairing vascular integrity in mice

by Surasak Wichaiyo, Sian Lax, Samantha J. Montague, Zhi Li, Beata Grygielska, Jeremy A. Pike, Elizabeth J. Haining, Alexander Brill, Steve P. Watson, Julie Rayes
Published 2019-08-01

Comparison of the GPVI inhibitors losartan and honokiol

by Marie-Blanche Onselaer, Magdolna Nagy, Chiara Pallini, Jeremy A Pike, Gina Perrella, Lourdes Garcia Quintanilla, Johannes A Eble, Natalie S. Poulter, Johan W.M. Heemskerk, Steve P Watson
Published 2020-02-01

High-throughput platelet spreading analysis: a tool for the diagnosis of platelet-based bleeding disorders

by Abdullah O. Khan, Annabel Maclachlan, Gillian C. Lowe, Phillip L.R. Nicolson, Rashid Al Ghaithi, Steven G. Thomas, Steve P. Watson, Jeremy A. Pike, Neil V. Morgan
Published 2020-03-01

Post-translational polymodification of β1-tubulin regulates motor protein localization in platelet production and function

by Abdullah O. Khan, Alexandre Slater, Annabel Maclachlan, Phillip L.R. Nicolson, Jeremy A. Pike, Jasmeet S. Reyat, Jack Yule, Rachel Stapley, Julie Rayes, Steven G. Thomas, Neil V. Morgan
Published 2020-12-01

Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins.

by Zahra Maqsood, Joanne C Clark, Eleyna M Martin, Yam Fung Hilaire Cheung, Luis A Morán, Sean E T Watson, Jeremy A Pike, Ying Di, Natalie S Poulter, Alexandre Slater, Bodo M H Lange, Bernhard Nieswandt, Johannes A Eble, Mike G Tomlinson, Dylan M Owen, David Stegner, Lloyd J Bridge, Christoph Wierling, Steve P Watson
Published 2022-11-01

Low-dose Btk inhibitors selectively block platelet activation by CLEC-2

by Phillip L.R. Nicolson, Sophie H. Nock, Joshua Hinds, Lourdes Garcia-Quintanilla, Christopher W. Smith, Joana Campos, Alexander Brill, Jeremy A. Pike, Abdullah O. Khan, Natalie S. Poulter, Diedre M. Kavanagh, Stephanie Watson, Callum N. Watson, Hayley Clifford, Aarnoud P. Huissoon, Alice Y. Pollitt, Johannes A. Eble, Guy Pratt, Steve P. Watson, Craig E. Hughes
Published 2020-01-01

Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift

by Yang Zhang, Laura Garcia-Ibanez, Carolin Ulbricht, Laurence S. C. Lok, Jeremy A. Pike, Jennifer Mueller-Winkler, Thomas W. Dennison, John R. Ferdinand, Cameron J. M. Burnett, Juan C. Yam-Puc, Lingling Zhang, Raul Maqueda Alfaro, Yousuke Takahama, Izumi Ohigashi, Geoffrey Brown, Tomohiro Kurosaki, Victor L. J. Tybulewicz, Antal Rot, Anja E. Hauser, Menna R. Clatworthy, Kai-Michael Toellner
Published 2022-05-01