Adaptation to HLA-associated immune pressure over the course of HIV infection and in circulating HIV-1 strains.

by Eric Alves, Marwah Al-Kaabi, Niamh M Keane, Shay Leary, Coral-Ann M Almeida, Pooja Deshpande, Jennifer Currenti, Abha Chopra, Rita Smith, Alison Castley, Simon Mallal, Spyros A Kalams, Silvana Gaudieri, Mina John
Published 2022-12-01

Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV.

by Jennifer Currenti, Abha Chopra, Mina John, Shay Leary, Elizabeth McKinnon, Eric Alves, Mark Pilkinton, Rita Smith, Louise Barnett, Wyatt J McDonnell, Michaela Lucas, Francine Noel, Simon Mallal, Joseph A Conrad, Spyros A Kalams, Silvana Gaudieri
Published 2019-12-01

Tracking of activated cTfh cells following sequential influenza vaccinations reveals transcriptional profile of clonotypes driving a vaccine-induced immune response

by Jennifer Currenti, Joshua Simmons, Jared Oakes, Silvana Gaudieri, Silvana Gaudieri, Silvana Gaudieri, Christian M. Warren, Rama Gangula, Eric Alves, Ramesh Ram, Shay Leary, Jesse D. Armitage, Rita M. Smith, Abha Chopra, Natasha B. Halasa, Mark A. Pilkinton, Spyros A. Kalams, Spyros A. Kalams
Published 2023-03-01

Cross-Reactivity to Mutated Viral Immune Targets Can Influence CD8+ T Cell Functionality: An Alternative Viral Adaptation Strategy

by Jennifer Currenti, Becker M.P. Law, Kai Qin, Mina John, Mina John, Mark A. Pilkinton, Anju Bansal, Shay Leary, Ramesh Ram, Abha Chopra, Rama Gangula, Ling Yue, Ling Yue, Christian Warren, Louise Barnett, Eric Alves, Wyatt J. McDonnell, Anuradha Sooda, Sonya L. Heath, Simon Mallal, Simon Mallal, Paul Goepfert, Spyros A. Kalams, Silvana Gaudieri, Silvana Gaudieri, Silvana Gaudieri
Published 2021-10-01