Complement opsonization of HIV-1 enhances the uptake by dendritic cells and involves the endocytic lectin and integrin receptor families.

by Veronica Tjomsland, Rada Ellegård, Karlhans Che, Jorma Hinkula, Jeffrey D Lifson, Marie Larsson
Published 2011-01-01

Distinct phenotype, longitudinal changes of numbers and cell-associated virus in blood dendritic cells in SIV-infected CD8-lymphocyte depleted macaques.

by Caroline Soulas, Patrick J Autissier, Tricia H Burdo, Michael Piatak, Jeffrey D Lifson, Kenneth C Williams
Published 2015-01-01

Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo

by Christine M. Fennessey, Celine Camus, Taina T. Immonen, Carolyn Reid, Frank Maldarelli, Jeffrey D. Lifson, Brandon F. Keele
Published 2019-04-01

AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity.

by Sebastian P Fuchs, José M Martinez-Navio, Michael Piatak, Jeffrey D Lifson, Guangping Gao, Ronald C Desrosiers
Published 2015-08-01

Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry.

by Rachid Sougrat, Alberto Bartesaghi, Jeffrey D Lifson, Adam E Bennett, Julian W Bess, Daniel J Zabransky, Sriram Subramaniam
Published 2007-05-01

HSV-2 infection of dendritic cells amplifies a highly susceptible HIV-1 cell target.

by Elena Martinelli, Hugo Tharinger, Ines Frank, James Arthos, Michael Piatak, Jeffrey D Lifson, James Blanchard, Agegnehu Gettie, Melissa Robbiani
Published 2011-06-01

In vivo binding and retention of CD4-specific DARPin 57.2 in macaques.

by Pavel Pugach, Anders Krarup, Agegnehu Gettie, Marcelo Kuroda, James Blanchard, Michael Piatak, Jeffrey D Lifson, Alexandra Trkola, Melissa Robbiani
Published 2010-08-01

Effects of treatment with suppressive combination antiretroviral drug therapy and the histone deacetylase inhibitor suberoylanilide hydroxamic acid; (SAHA) on SIV-infected Chinese...

by Binhua Ling, Michael Piatak, Linda Rogers, Ann-Marie Johnson, Kasi Russell-Lodrigue, Daria J Hazuda, Jeffrey D Lifson, Ronald S Veazey
Published 2014-01-01

Predictors of SIV recrudescence following antiretroviral treatment interruption

by Mykola Pinkevych, Christine M Fennessey, Deborah Cromer, Carolyn Reid, Charles M Trubey, Jeffrey D Lifson, Brandon F Keele, Miles P Davenport
Published 2019-10-01

18 Expanded clones in SIV-infected macaques on antiretroviral therapy recapitulate key features of expanded clones in HIV infection: implications for evaluation of ‘HIV cure’ inter...

by Xiaolin Wu, GregoryQ Del Prete, Andrea Ferris, AdrienneE Swanstrom, DavidW Wells, Shuang Guo, Stephen Hughes, JeffreyD Lifson
Published 2017-07-01

Long-Term Delivery of an Anti-SIV Monoclonal Antibody With AAV

by José M. Martinez-Navio, Sebastian P. Fuchs, Desiree E. Mendes, Eva G. Rakasz, Guangping Gao, Jeffrey D. Lifson, Ronald C. Desrosiers
Published 2020-03-01

Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques.

by Aidin Tavakoli-Tameh, Sanath Kumar Janaka, Katie Zarbock, Shelby O'Connor, Kristin Crosno, Saverio Capuano, Hajime Uno, Jeffrey D Lifson, David T Evans
Published 2020-04-01

Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir.

by Taina T Immonen, Christine M Fennessey, Leslie Lipkey, Abigail Thorpe, Gregory Q Del Prete, Jeffrey D Lifson, Miles P Davenport, Brandon F Keele
Published 2021-06-01

Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model.

by Christopher Kline, Jean Ndjomou, Tamera Franks, Rebecca Kiser, Vicky Coalter, Jeremy Smedley, Michael Piatak, John W Mellors, Jeffrey D Lifson, Zandrea Ambrose
Published 2013-01-01

A tonsillar PolyICLC/AT-2 SIV therapeutic vaccine maintains low viremia following antiretroviral therapy cessation.

by Panagiotis Vagenas, Meropi Aravantinou, Vennansha G Williams, Edith Jasny, Michael Piatak, Jeffrey D Lifson, Andres M Salazar, James L Blanchard, Agegnehu Gettie, Melissa Robbiani
Published 2010-09-01

HSV-2-driven increase in the expression of α4β7 correlates with increased susceptibility to vaginal SHIV(SF162P3) infection.

by Diana Goode, Rosaline Truong, Guillermo Villegas, Giulia Calenda, Natalia Guerra-Perez, Michael Piatak, Jeffrey D Lifson, James Blanchard, Agegnehu Gettie, Melissa Robbiani, Elena Martinelli
Published 2014-12-01

No evidence for ongoing replication on ART in SIV-infected macaques

by Taina T. Immonen, Christine M. Fennessey, Leslie Lipkey, Laura Newman, Agatha Macairan, Marjorie Bosche, Nora Waltz, Gregory Q. Del Prete, Jeffrey D. Lifson, Brandon F. Keele
Published 2024-06-01

Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans.

by Andrea L Ferris, David W Wells, Shuang Guo, Gregory Q Del Prete, Adrienne E Swanstrom, John M Coffin, Xiaolin Wu, Jeffrey D Lifson, Stephen H Hughes
Published 2019-07-01

Immunization with single-cycle SIV significantly reduces viral loads after an intravenous challenge with SIV(mac)239.

by Bin Jia, Sharon K Ng, M Quinn DeGottardi, Michael Piatak, Eloísa Yuste, Angela Carville, Keith G Mansfield, Wenjun Li, Barbra A Richardson, Jeffrey D Lifson, David T Evans
Published 2009-01-01

Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission.

by Jeremy Smedley, Baris Turkbey, Marcelino L Bernardo, Gregory Q Del Prete, Jacob D Estes, Gary L Griffiths, Hisataka Kobayashi, Peter L Choyke, Jeffrey D Lifson, Brandon F Keele
Published 2014-01-01