Is There a Place for Immunotherapy for Metastatic Microsatellite Stable Colorectal Cancer?

by François Ghiringhelli, Jean-David Fumet
Published 2019-08-01

FOLFIRI-bevacizumab as a second-line treatment for advanced biliary tract cancer after gemcitabine-based chemotherapy

by Nicolas Roussot, Nicolas Roussot, Nicolas Roussot, Nicolas Roussot, Julie Vincent, Remi Palmier, Guillaume Constantin, Leila Bengrine, Jean-David Fumet, Jean-David Fumet, Jean-David Fumet, Jean-David Fumet, François Ghiringhelli, François Ghiringhelli, François Ghiringhelli, François Ghiringhelli, François Ghiringhelli
Published 2023-11-01

Targeting BRAF and RAS in Colorectal Cancer

by Helene Bellio, Jean David Fumet, Francois Ghiringhelli
Published 2021-05-01

Immunogenic Cell Death and Elimination of Immunosuppressive Cells: A Double-Edged Sword of Chemotherapy

by Jean-David Fumet, Emeric Limagne, Marion Thibaudin, Francois Ghiringhelli
Published 2020-09-01

Precision medicine phase II study evaluating the efficacy of a double immunotherapy by durvalumab and tremelimumab combined with olaparib in patients with solid cancers and carrier...

by Jean-David Fumet, Emeric Limagne, Marion Thibaudin, Caroline Truntzer, Aurélie Bertaut, Emilie Rederstorff, Francois Ghiringhelli
Published 2020-08-01

346 Translational program of the phase II MEDITREME trial: identification of prognostic factors for response to durvalumab and tremelimumab in combination with FOLFOX in metastatic...

by Francois Ghiringhelli, Emeric Limagne, Marion Thibaudin, Caroline Truntzer, Olivier Adotevi, Caroline Laheurte, Elise Ballot, Jean-David Fumet
Published 2021-11-01

Successfully treatment by eribulin in visceral crisis: a case of lymphangitic carcinomatosis from metastatic breast cancer

by Jean-David Fumet, Mark Wickre, Jean-Philippe Jacquot, Marie-Helene Bizollon, Adrien Melis, André Vanoli, Erika Viel
Published 2018-08-01

Tim-3/galectin-9 pathway and mMDSC control primary and secondary resistances to PD-1 blockade in lung cancer patients

by Emeric Limagne, Corentin Richard, Marion Thibaudin, Jean-David Fumet, Caroline Truntzer, Aurélie Lagrange, Laure Favier, Bruno Coudert, François Ghiringhelli
Published 2019-04-01

Angiotensin-converting enzyme (ACE) inhibitor prescription affects non-small-cell lung cancer (NSCLC) patients response to PD-1/PD-L1 immune checkpoint blockers

by Soleine Medjebar, Caroline Truntzer, Anaïs Perrichet, Emeric Limagne, Jean-David Fumet, Corentin Richard, Arielle Elkrief, Bertrand Routy, Cédric Rébé, François Ghiringhelli
Published 2020-01-01

Population Pharmacokinetics of Palbociclib in a Real-World Situation

by Bernard Royer, Courèche Kaderbhaï, Jean-David Fumet, Audrey Hennequin, Isabelle Desmoulins, Sylvain Ladoire, Siavoshe Ayati, Didier Mayeur, Sivia Ilie, Antonin Schmitt
Published 2021-02-01

Phase I Dose-Escalation Trial of an Innovative Chemotherapy Regimen Combining a Fractionated Dose of Irinotecan Plus Bevacizumab, Oxaliplatin, 5-Fluorouracil, and Folinic Acid (bFO...

by Hélène Bellio, Aurélie Bertaut, Alice Hervieu, Sylvie Zanetta, Audrey Hennequin, Julie Vincent, Rémi Palmier, Leila Bengrine-Lefevre, François Ghiringhelli, Jean-David Fumet
Published 2021-10-01

TCR Clonality and Genomic Instability Signatures as Prognostic Biomarkers in High Grade Serous Ovarian Cancer

by Julie Lecuelle, Romain Boidot, Hugo Mananet, Valentin Derangère, Juliette Albuisson, Vincent Goussot, Laurent Arnould, Zoé Tharin, Isabelle Ray Coquard, François Ghiringhelli, Caroline Truntzer, Jean-David Fumet
Published 2021-08-01

Pharmacokinetic/Pharmacodynamic Model of Neutropenia in Real-Life Palbociclib-Treated Patients

by Alexandre Le Marouille, Emma Petit, Courèche Kaderbhaï, Isabelle Desmoulins, Audrey Hennequin, Didier Mayeur, Jean-David Fumet, Sylvain Ladoire, Zoé Tharin, Siavoshe Ayati, Silvia Ilie, Bernard Royer, Antonin Schmitt
Published 2021-10-01

Optimized fractionated radiotherapy with anti-PD-L1 and anti-TIGIT: a promising new combination

by Mathieu Grapin, Corentin Richard, Emeric Limagne, Romain Boidot, Véronique Morgand, Aurélie Bertaut, Valentin Derangere, Pierre-Antoine Laurent, Marion Thibaudin, Jean David Fumet, Gilles Crehange, François Ghiringhelli, Céline Mirjolet
Published 2019-06-01

Improving olaparib exposure to optimize adverse effects management

by Marylise Sterlé, Alicja Puszkiel, Chloé Burlot, Eva Pereira, Audrey Bellesoeur, Sixtine De Percin, Guillaume Beinse, Jean-David Fumet, Laure Favier, Julie Niogret, Benoit Blanchet, Bernard Royer, Leïla Bengrine-Lefevre, Antonin Schmitt
Published 2024-04-01

Response to first line chemotherapy regimen is associated with efficacy of nivolumab in non-small-cell lung cancer

by Courèche-Guillaume Kaderbhai, Corentin Richard, Jean David Fumet, Anne Aarnink, Sandra Ortiz-Cuaran, Maurice Pérol, Pascal Foucher, Bruno Coudert, Laure Favier, Aurélie Lagrange, Emeric Limagne, Romain Boidot, Sylvain Ladoire, Michel Poudenx, Marius Ilie, Paul Hofman, Pierre Saintigny, François Ghiringhelli
Published 2017-09-01

Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung can...

by François Ghiringhelli, Frederic Bibeau, Laurent Greillier, Jean-David Fumet, Alis Ilie, Florence Monville, Caroline Laugé, Aurélie Catteau, Isabelle Boquet, Amine Majdi, Erwan Morgand, Youssef Oulkhouir, Nicolas Brandone, Julien Adam, Thomas Sbarrato, Alboukadel Kassambara, Jacques Fieschi, Stéphane Garcia, Anne Laure Lepage, Pascale Tomasini, Jérôme Galon
Published 2023-06-01

Implementation and use of whole exome sequencing for metastatic solid cancer

by Manon Réda, Corentin Richard, Aurelie Bertaut, Julie Niogret, Thomas Collot, Jean David Fumet, Julie Blanc, Caroline Truntzer, Isabelle Desmoulins, Sylvain Ladoire, Audrey Hennequin, Laure Favier, Leila Bengrine, Julie Vincent, Alice Hervieu, Jean-Florian Guion Dusserre, Come Lepage, Pascal Foucher, Christophe Borg, Juliette Albuisson, Laurent Arnould, Sophie Nambot, Laurence Faivre, Romain Boidot, Francois Ghiringhelli
Published 2020-01-01

A phase I study of the combination of atezolizumab, tiragolumab, and stereotactic body radiation therapy in patients with metastatic multiorgan cancer

by Nicolas Roussot, Jean-David Fumet, Emeric Limagne, Marion Thibaudin, Alice Hervieu, Audrey Hennequin, Sylvie Zanetta, Lorraine Dalens, Théo Fourrier, Loick Galland, Pierre Jacob, Aurélie Bertaut, Emilie Rederstorff, Cédric Chevalier, Sarah Ghirardi, Elodie Gilbert, Azzat Khoukaz, Etienne Martin, Constance Nicolet, Magali Quivrin, David Thibouw, Noémie Vulquin, Gilles Truc, Magali Rouffiac, Francois Ghiringhelli, Céline Mirjolet
Published 2023-11-01

Therapeutic Challenges in Patients with Gynecologic Carcinosarcomas: Analysis of a Multicenter National Cohort Study from the French Prospective TMRG Network

by Clémence Romeo, Olivia Le Saux, Margaux Jacobs, Florence Joly, Gwenael Ferron, Laure Favier, Jean-David Fumet, Nicolas Isambert, Pierre-Emmanuel Colombo, Renaud Sabatier, Ludovic Bastide, Amandine Charreton, Mojgan Devouassoux-Shisheboran, Witold Gertych, Coraline Dubot, Diana Bello Roufai, Guillaume Bataillon, Dominique Berton, Elsa Kalbacher, Patricia Pautier, Christophe Pomel, Caroline Cornou, Isabelle Treilleux, Audrey Lardy-Cleaud, Isabelle Ray-Coquard
Published 2022-01-01