Towards a Standardised Method to Acquire and Store Liver Samples and Guidelines to Improve Quality Control and Exchange of Relative Expression Data

by Frank M. Riemers, Jan Rothuizen, Louis C. Penning
Published 2013-12-01

Sex specific differences in hepatic and plasma lipid profiles in healthy cats pre and post spaying and neutering: relationship with feline hepatic lipidosis

by Chiara Valtolina, Arie B. Vaandrager, Robert P. Favier, Maidina Tuohetahuntila, Anne Kummeling, Isabelle Jeusette, Jan Rothuizen, Joris H. Robben
Published 2017-08-01

Efficacy of orally administered sodium benzoate and sodium phenylbutyrate in dogs with congenital portosystemic shunts

by Giora van Straten, Diewke vanDalen, Sietske J. Mesu, Jan Rothuizen, Erik Teske, Bart Spee, Robert P. Favier, Ingeborg M. vanGeijlswijk
Published 2019-05-01

COMMD1-deficient dogs accumulate copper in hepatocytes and provide a good model for chronic hepatitis and fibrosis.

by Robert P Favier, Bart Spee, Baukje A Schotanus, Ted S G A M van den Ingh, Hille Fieten, Bas Brinkhof, Cornelia S Viebahn, Louis C Penning, Jan Rothuizen
Published 2012-01-01

Gene expression patterns in the progression of canine copper-associated chronic hepatitis.

by Karen Dirksen, Bart Spee, Louis C Penning, Ted S G A M van den Ingh, Iwan A Burgener, Adrian L Watson, Marian Groot Koerkamp, Jan Rothuizen, Frank G van Steenbeek, Hille Fieten
Published 2017-01-01

Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts.

by Giora van Straten, Frank G van Steenbeek, Guy C M Grinwis, Robert P Favier, Anne Kummeling, Ingrid H van Gils, Hille Fieten, Marian J A Groot Koerkamp, Frank C P Holstege, Jan Rothuizen, Bart Spee
Published 2014-01-01

Altered subcellular localization of heat shock protein 90 is associated with impaired expression of the aryl hydrocarbon receptor pathway in dogs.

by Frank G van Steenbeek, Bart Spee, Louis C Penning, Anne Kummeling, Ingrid H M van Gils, Guy C M Grinwis, Dik Van Leenen, Frank C P Holstege, Manon Vos-Loohuis, Jan Rothuizen, Peter A J Leegwater
Published 2013-01-01

Aberrant gene expression in dogs with portosystemic shunts.

by Frank G van Steenbeek, Lindsay Van den Bossche, Guy C M Grinwis, Anne Kummeling, Ingrid H M van Gils, Marian J A Groot Koerkamp, Dik van Leenen, Frank C P Holstege, Louis C Penning, Jan Rothuizen, Peter A J Leegwater, Bart Spee
Published 2013-01-01

Correction: Aberrant Gene Expression in Dogs with Portosystemic Shunts.

by Frank G. van Steenbeek, Lindsay Van den Bossche, Guy C. M. Grinwis, Anne Kummeling, Ingrid H. M. van Gils, Marian J. A. Groot. Koerkamp, Dik van Leenen, Frank C. P. Holstege, Louis C. Penning, Jan Rothuizen, Peter A. J. Leegwater, Bart Spee
Published 2013-01-01

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

by Sathidpak Nantasanti, Bart Spee, Hedwig S. Kruitwagen, Chen Chen, Niels Geijsen, Loes A. Oosterhoff, Monique E. van Wolferen, Nicolas Pelaez, Hille Fieten, Richard W. Wubbolts, Guy C. Grinwis, Jefferson Chan, Meritxell Huch, Robert R.G. Vries, Hans Clevers, Alain de Bruin, Jan Rothuizen, Louis C. Penning, Baukje A. Schotanus
Published 2015-11-01

Aberrant hepatic lipid storage and metabolism in canine portosystemic shunts.

by Lindsay Van den Bossche, Vivien A C Schoonenberg, Iwan A Burgener, Louis C Penning, Ingrid M Schrall, Hedwig S Kruitwagen, Monique E van Wolferen, Guy C M Grinwis, Anne Kummeling, Jan Rothuizen, Jeroen F van Velzen, Nikolas Stathonikos, Martijn R Molenaar, Bernd J Helms, Jos F H M Brouwers, Bart Spee, Frank G van Steenbeek
Published 2017-01-01

The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: a new canine model for copper-metabolism disorders

by Hille Fieten, Yadvinder Gill, Alan J. Martin, Mafalda Concilli, Karen Dirksen, Frank G. van Steenbeek, Bart Spee, Ted S. G. A. M. van den Ingh, Ellen C. C. P. Martens, Paola Festa, Giancarlo Chesi, Bart van de Sluis, Roderick H. J. H. Houwen, Adrian L. Watson, Yurii S. Aulchenko, Victoria L. Hodgkinson, Sha Zhu, Michael J. Petris, Roman S. Polishchuk, Peter A. J. Leegwater, Jan Rothuizen
Published 2016-01-01

Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

by Hedwig S. Kruitwagen, Loes A. Oosterhoff, Ingrid G.W.H. Vernooij, Ingrid M. Schrall, Monique E. van Wolferen, Farah Bannink, Camille Roesch, Lisa van Uden, Martijn R. Molenaar, J. Bernd Helms, Guy C.M. Grinwis, Monique M.A. Verstegen, Luc J.W. van der Laan, Meritxell Huch, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Published 2017-04-01

Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a <i>COMMD1</i>-Deficient Dog Model of Metabolic Liver Disease

by Hedwig S. Kruitwagen, Loes A. Oosterhoff, Monique E. van Wolferen, Chen Chen, Sathidpak Nantasanti Assawarachan, Kerstin Schneeberger, Anne Kummeling, Giora van Straten, Ies C. Akkerdaas, Christel R. Vinke, Frank G. van Steenbeek, Leonie W.L. van Bruggen, Jeannette Wolfswinkel, Guy C.M. Grinwis, Sabine A. Fuchs, Helmuth Gehart, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Published 2020-02-01