Thrombin-cleaved syndecan-3/-4 ectodomain fragments mediate endothelial barrier dysfunction.

by Melanie Jannaway, Xiaoyuan Yang, Jamie E Meegan, Danielle C Coleman, Sarah Y Yuan
Published 2019-01-01

Role of Neutrophil Extracellular Traps and Vesicles in Regulating Vascular Endothelial Permeability

by Yonggang Ma, Xiaoyuan Yang, Victor Chatterjee, Jamie E. Meegan, Richard S. Beard Jr., Sarah Y. Yuan, Sarah Y. Yuan
Published 2019-05-01

Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- γC- terminal fragments.

by Xiaohua Guo, Rebecca A Eitnier, Richard S Beard, Jamie E Meegan, Xiaoyuan Yang, Alexandra M Aponte, Fang Wang, Peter R Nelson, Mack H Wu
Published 2020-01-01

Transpulmonary generation of cell‐free hemoglobin contributes to vascular dysfunction in pulmonary arterial hypertension via dysregulated clearance mechanisms

by Jamie E. Meegan, Vern Eric Kerchberger, Niki L. Fortune, Joel Brennan McNeil, Julie A. Bastarache, Eric D. Austin, Lorraine B. Ware, Anna R. Hemnes, Evan L. Brittain
Published 2023-01-01

Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome

by Richard S. Beard, Xiaoyuan Yang, Jamie E. Meegan, Jonathan W. Overstreet, Clement G.Y. Yang, John A. Elliott, Jason J. Reynolds, Byeong J. Cha, Christopher D. Pivetti, David A. Mitchell, Mack H. Wu, Robert J. Deschenes, Sarah Y. Yuan
Published 2016-09-01

Blocking P2X7 receptor with AZ 10606120 exacerbates vascular hyperpermeability and inflammation in murine polymicrobial sepsis

by Jamie E. Meegan, Padmini Komalavilas, Joyce Cheung‐Flynn, Tsz Wing Yim, Nathan D. Putz, Jordan J. Jesse, Kyle D. Smith, Tatiana N. Sidorova, Han Noo Ri Lee, Toria Tomasek, Ciara M. Shaver, Lorraine B. Ware, Colleen M. Brophy, Julie A. Bastarache
Published 2022-06-01

Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis.

by Jamie E Meegan, Ciara M Shaver, Nathan D Putz, Jordan J Jesse, Stuart R Landstreet, Han Noo Ri Lee, Tatiana N Sidorova, J Brennan McNeil, James L Wynn, Joyce Cheung-Flynn, Padmini Komalavilas, Colleen M Brophy, Lorraine B Ware, Julie A Bastarache
Published 2020-01-01