SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity.

by Hongying Yang, Wei Zhang, Heng Pan, Heidi G Feldser, Elden Lainez, Christine Miller, Stewart Leung, Zhong Zhong, Huizhen Zhao, Sharon Sweitzer, Thomas Considine, Thomas Riera, Vipin Suri, Brian White, James L Ellis, George P Vlasuk, Christine Loh
Published 2012-01-01

The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet

by Sarah J. Mitchell, Alejandro Martin-Montalvo, Evi M. Mercken, Hector H. Palacios, Theresa M. Ward, Gelareh Abulwerdi, Robin K. Minor, George P. Vlasuk, James L. Ellis, David A. Sinclair, John Dawson, David B. Allison, Yongqing Zhang, Kevin G. Becker, Michel Bernier, Rafael de Cabo
Published 2014-03-01