The Effect of Deuteration and Homologation of the Lactam Ring of Nirmatrelvir on Its Biochemical Properties and Oxidative Metabolism

by Elena Arutyunova, Alexandr Belovodskiy, Pu Chen, Muhammad Bashir Khan, Michael Joyce, Holly Saffran, Jimmy Lu, Zoe Turner, Bing Bai, Tess Lamer, Howard S. Young, John C. Vederas, D. Lorne Tyrrell, M. Joanne Lemieux, James A. Nieman
Published 2023-11-01

HIV capsid is a tractable target for small molecule therapeutic intervention.

by Wade S Blair, Chris Pickford, Stephen L Irving, David G Brown, Marie Anderson, Richard Bazin, Joan Cao, Giuseppe Ciaramella, Jason Isaacson, Lynn Jackson, Rachael Hunt, Anne Kjerrstrom, James A Nieman, Amy K Patick, Manos Perros, Andrew D Scott, Kevin Whitby, Hua Wu, Scott L Butler
Published 2010-01-01