Harnessing Wolbachia cytoplasmic incompatibility alleles for confined gene drive: A modeling study.

by Jiahe Li, Jackson Champer
Published 2023-01-01

Assessment of distant-site rescue elements for CRISPR toxin-antidote gene drives

by Jingheng Chen, Xuejiao Xu, Jackson Champer
Published 2023-02-01

Analysis of the surface, secreted, and intracellular proteome of Propionibacterium acnes

by Yang Yu, Jackson Champer, Jenny Kim
Published 2015-12-01

Proteomic Analysis of Pathogenic Fungi Reveals Highly Expressed Conserved Cell Wall Proteins

by Jackson Champer, James I. Ito, Karl V. Clemons, David A. Stevens, Markus Kalkum
Published 2016-01-01

Experimental demonstration of tethered gene drive systems for confined population modification or suppression

by Matthew Metzloff, Emily Yang, Sumit Dhole, Andrew G. Clark, Philipp W. Messer, Jackson Champer
Published 2022-05-01

Performance analysis of novel toxin-antidote CRISPR gene drive systems

by Jackson Champer, Isabel K. Kim, Samuel E. Champer, Andrew G. Clark, Philipp W. Messer
Published 2020-03-01

Design and analysis of CRISPR‐based underdominance toxin‐antidote gene drives

by Jackson Champer, Samuel E. Champer, Isabel K. Kim, Andrew G. Clark, Philipp W. Messer
Published 2021-04-01

Anopheles homing suppression drive candidates exhibit unexpected performance differences in simulations with spatial structure

by Samuel E Champer, Isabel K Kim, Andrew G Clark, Philipp W Messer, Jackson Champer
Published 2022-10-01

A toxin-antidote CRISPR gene drive system for regional population modification

by Jackson Champer, Esther Lee, Emily Yang, Chen Liu, Andrew G. Clark, Philipp W. Messer
Published 2020-02-01

Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning framework.

by Samuel E Champer, Nathan Oakes, Ronin Sharma, Pablo García-Díaz, Jackson Champer, Philipp W Messer
Published 2021-12-01

A small-molecule approach to restore female sterility phenotype targeted by a homing suppression gene drive in the fruit pest Drosophila suzukii.

by Suhan Ma, Xuyang Ni, Shimin Chen, Xiaomu Qiao, Xuejiao Xu, Weizhe Chen, Jackson Champer, Jia Huang
Published 2024-04-01

Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations.

by Jackson Champer, Riona Reeves, Suh Yeon Oh, Chen Liu, Jingxian Liu, Andrew G Clark, Philipp W Messer
Published 2017-07-01

A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles

by Emily Yang, Matthew Metzloff, Anna M Langmüller, Xuejiao Xu, Andrew G Clark, Philipp W Messer, Jackson Champer
Published 2022-04-01

Molecular safeguarding of CRISPR gene drive experiments

by Jackson Champer, Joan Chung, Yoo Lim Lee, Chen Liu, Emily Yang, Zhaoxin Wen, Andrew G Clark, Philipp W Messer
Published 2019-01-01

Germline Cas9 promoters with improved performance for homing gene drive

by Jie Du, Weizhe Chen, Xihua Jia, Xuejiao Xu, Emily Yang, Ruizhi Zhou, Yuqi Zhang, Matt Metzloff, Philipp W. Messer, Jackson Champer
Published 2024-05-01

Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations

by Anna M Langmüller, Jackson Champer, Sandra Lapinska, Lin Xie, Matthew Metzloff, Samuel E Champer, Jingxian Liu, Yineng Xu, Jie Du, Andrew G Clark, Philipp W Messer
Published 2022-09-01