QPI Allows in vitro Drug Screening of Triple Negative Breast Cancer PDX Tumors and Fine Needle Biopsies

by Graeme F. Murray, Tia H. Turner, Tia H. Turner, Daniel Guest, Kevin A. Leslie, Mohammad A. Alzubi, Senthil K. Radhakrishnan, Senthil K. Radhakrishnan, J. Chuck Harrell, J. Chuck Harrell, Jason Reed, Jason Reed
Published 2019-10-01

The Transformative Role of 3D Culture Models in Triple-Negative Breast Cancer Research

by Xavier S. Bittman-Soto, Evelyn S. Thomas, Madeline E. Ganshert, Laura L. Mendez-Santacruz, J. Chuck Harrell
Published 2024-05-01

Serine residues 726 and 780 have nonredundant roles regulating STAT5a activity in luminal breast cancer

by Alicia E. Woock, Jacqueline M. Grible, Amy L. Olex, J. Chuck Harrell, Patricija Zot, Michael Idowu, Charles V. Clevenger
Published 2021-06-01

Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells

by Christopher Dravis, Benjamin T. Spike, J. Chuck Harrell, Claire Johns, Christy L. Trejo, E. Michelle Southard-Smith, Charles M. Perou, Geoffrey M. Wahl
Published 2015-09-01

Identification of nuclear export inhibitor-based combination therapies in preclinical models of triple-negative breast cancer

by Narmeen S. Rashid, Nicole S. Hairr, Graeme Murray, Amy L. Olex, Tess J. Leftwich, Jacqueline M. Grible, Jason Reed, Mikhail G. Dozmorov, J. Chuck Harrell
Published 2021-12-01

The human intermediate prolactin receptor is a mammary proto-oncogene

by Jacqueline M. Grible, Patricija Zot, Amy L. Olex, Shannon E. Hedrick, J. Chuck Harrell, Alicia E. Woock, Michael O. Idowu, Charles V. Clevenger
Published 2021-03-01

Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer

by Holly A. Byers, Amy N. Brooks, Janakiram R. Vangala, Jacqueline M. Grible, Alex Feygin, Charles V. Clevenger, J. Chuck Harrell, Senthil K. Radhakrishnan
Published 2023-09-01

New generation breast cancer cell lines developed from patient-derived xenografts

by Jessica Finlay-Schultz, Britta M. Jacobsen, Duncan Riley, Kiran V. Paul, Scott Turner, Andrea Ferreira-Gonzalez, J. Chuck Harrell, Peter Kabos, Carol A. Sartorius
Published 2020-06-01

The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours

by Arian Lundberg, Linda S. Lindström, Jingmei Li, J. Chuck Harrell, Eva Darai-Ramqvist, Emmanouil G. Sifakis, Theodoros Foukakis, Charles M. Perou, Kamila Czene, Jonas Bergh, Nicholas P. Tobin
Published 2019-02-01

Sphingosine kinase 1 activation by estrogen receptor α36 contributes to tamoxifen resistance in breast cancer

by Melissa A. Maczis, Michael Maceyka, Michael R. Waters, Jason Newton, Manjulata Singh, Madisyn F. Rigsby, Tia H. Turner, Mohammad A. Alzubi, J. Chuck Harrell, Sheldon Milstien, Sarah Spiegel
Published 2018-12-01

Separation of breast cancer and organ microenvironment transcriptomes in metastases

by Mohammad A. Alzubi, Tia H. Turner, Amy L. Olex, Sahib S. Sohal, Nicholas P. Tobin, Susana G. Recio, Jonas Bergh, Thomas Hatschek, Joel S. Parker, Carol A. Sartorius, Charles M. Perou, Mikhail G. Dozmorov, J. Chuck Harrell
Published 2019-03-01

Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies

by Tanmoy Mondal, Gururaj N Shivange, Rachisan GT Tihagam, Evan Lyerly, Michael Battista, Divpriya Talwar, Roxanna Mosavian, Karol Urbanek, Narmeen S Rashid, J Chuck Harrell, Paula D Bos, Edward B Stelow, M Sharon Stack, Sanchita Bhatnagar, Jogender Tushir‐Singh
Published 2021-03-01

Stratification of Tamoxifen Synergistic Combinations for the Treatment of ER+ Breast Cancer

by Emily K. Zboril, Jacqueline M. Grible, David C. Boyd, Nicole S. Hairr, Tess J. Leftwich, Madelyn F. Esquivel, Alex K. Duong, Scott A. Turner, Andrea Ferreira-Gonzalez, Amy L. Olex, Carol A. Sartorius, Mikhail G. Dozmorov, J. Chuck Harrell
Published 2023-06-01

Discovering Synergistic Compounds with BYL-719 in PI3K Overactivated Basal-like PDXs

by David C. Boyd, Emily K. Zboril, Amy L. Olex, Tess J. Leftwich, Nicole S. Hairr, Holly A. Byers, Aaron D. Valentine, Julia E. Altman, Mohammad A. Alzubi, Jacqueline M. Grible, Scott A. Turner, Andrea Ferreira-Gonzalez, Mikhail G. Dozmorov, J. Chuck Harrell
Published 2023-03-01

Transcriptomic changes underlying EGFR inhibitor resistance in human and mouse models of basal-like breast cancer

by Narmeen S. Rashid, David C. Boyd, Amy L. Olex, Jacqueline M. Grible, Alex K. Duong, Mohammad A. Alzubi, Julia E. Altman, Tess J. Leftwich, Aaron D. Valentine, Nicole S. Hairr, Emily K. Zboril, Timothy M. Smith, Adam D. Pfefferle, Mikhail G. Dozmorov, J. Chuck Harrell
Published 2022-12-01

Publisher Correction: Rewiring of the 3D genome during acquisition of carboplatin resistance in a triple-negative breast cancer patient-derived xenograft

by Mikhail G. Dozmorov, Maggie A. Marshall, Narmeen S. Rashid, Jacqueline M. Grible, Aaron Valentine, Amy L. Olex, Kavita Murthy, Abhijit Chakraborty, Joaquin Reyna, Daniela Salgado Figueroa, Laura Hinojosa-Gonzalez, Erika Da-Inn Lee, Brittany A. Baur, Sushmita Roy, Ferhat Ay, J. Chuck Harrell
Published 2023-05-01

Rewiring of the 3D genome during acquisition of carboplatin resistance in a triple-negative breast cancer patient-derived xenograft

by Mikhail G. Dozmorov, Maggie A. Marshall, Narmeen S. Rashid, Jacqueline M. Grible, Aaron Valentine, Amy L. Olex, Kavita Murthy, Abhijit Chakraborty, Joaquin Reyna, Daniela Salgado Figueroa, Laura Hinojosa-Gonzalez, Erika Da-Inn Lee, Brittany A. Baur, Sushmita Roy, Ferhat Ay, J. Chuck Harrell
Published 2023-04-01

Taxonomy of breast cancer based on normal cell phenotype predicts outcome

by Santagata, Sandro, Thakkar, Ankita, Ergonul, Ayse, Wang, Bin, Woo, Terri, Hu, Rong, Harrell, J. Chuck, McNamara, George, Schwede, Matthew, Culhane, Aedin, Kindelberger, David, Rodig, Scott J., Richardson, Andrea, Schnitt, Stuart Jay, Tamimi, Rulla May, Ince, Tan A.
Published 2016