Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes

by Nicholas Bowker, Rupal L. Shah, Stephen J. Sharp, Jian'an Luan, Isobel D. Stewart, Eleanor Wheeler, Manuel A.R. Ferreira, Aris Baras, Nicholas J. Wareham, Claudia Langenberg, Luca A. Lotta
Published 2020-11-01

The Relationship of Maternal Gestational Mass Spectrometry-Derived Metabolites with Offspring Congenital Heart Disease: Results from Multivariable and Mendelian Randomization Analy...

by Kurt Taylor, Nancy McBride, Jian Zhao, Sam Oddie, Rafaq Azad, John Wright, Ole A. Andreassen, Isobel D. Stewart, Claudia Langenberg, Maria Christine Magnus, Maria Carolina Borges, Massimo Caputo, Deborah A. Lawlor
Published 2022-07-01

Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation studyResearch in context

by Jian Zhao, Isobel D. Stewart, Denis Baird, Dan Mason, John Wright, Jie Zheng, Tom R. Gaunt, David M. Evans, Rachel M. Freathy, Claudia Langenberg, Nicole M. Warrington, Deborah A. Lawlor, Maria Carolina Borges
Published 2023-02-01

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease

by Johannes Hertel, Amy C. Harms, Almut Heinken, Federico Baldini, Cyrille C. Thinnes, Enrico Glaab, Daniel A. Vasco, Maik Pietzner, Isobel D. Stewart, Nicholas J. Wareham, Claudia Langenberg, Claudia Trenkwalder, Rejko Krüger, Thomas Hankemeier, Ronan M.T. Fleming, Brit Mollenhauer, Ines Thiele
Published 2019-11-01

Assessing the causal association of glycine with risk of cardio-metabolic diseases

by Laura B. L. Wittemans, Luca A. Lotta, Clare Oliver-Williams, Isobel D. Stewart, Praveen Surendran, Savita Karthikeyan, Felix R. Day, Albert Koulman, Fumiaki Imamura, Lingyao Zeng, Jeanette Erdmann, Heribert Schunkert, Kay-Tee Khaw, Julian L. Griffin, Nita G. Forouhi, Robert A. Scott, Angela M. Wood, Stephen Burgess, Joanna M. M. Howson, John Danesh, Nicholas J. Wareham, Adam S. Butterworth, Claudia Langenberg
Published 2019-03-01

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.

by Luca A Lotta, Robert A Scott, Stephen J Sharp, Stephen Burgess, Jian'an Luan, Therese Tillin, Amand F Schmidt, Fumiaki Imamura, Isobel D Stewart, John R B Perry, Luke Marney, Albert Koulman, Edward D Karoly, Nita G Forouhi, Rasmus J O Sjögren, Erik Näslund, Juleen R Zierath, Anna Krook, David B Savage, Julian L Griffin, Nishi Chaturvedi, Aroon D Hingorani, Kay-Tee Khaw, Inês Barroso, Mark I McCarthy, Stephen O'Rahilly, Nicholas J Wareham, Claudia Langenberg
Published 2016-11-01

The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.

by Florence Guida, Vanessa Y Tan, Laura J Corbin, Karl Smith-Byrne, Karine Alcala, Claudia Langenberg, Isobel D Stewart, Adam S Butterworth, Praveen Surendran, David Achaintre, Jerzy Adamski, Pilar Amiano, Manuela M Bergmann, Caroline J Bull, Christina C Dahm, Audrey Gicquiau, Graham G Giles, Marc J Gunter, Toomas Haller, Arnulf Langhammer, Tricia L Larose, Börje Ljungberg, Andres Metspalu, Roger L Milne, David C Muller, Therese H Nøst, Elin Pettersen Sørgjerd, Cornelia Prehn, Elio Riboli, Sabina Rinaldi, Joseph A Rothwell, Augustin Scalbert, Julie A Schmidt, Gianluca Severi, Sabina Sieri, Roel Vermeulen, Emma E Vincent, Melanie Waldenberger, Nicholas J Timpson, Mattias Johansson
Published 2021-09-01

The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.

by Ju-Sheng Zheng, Jian'an Luan, Eleni Sofianopoulou, Stephen J Sharp, Felix R Day, Fumiaki Imamura, Thomas E Gundersen, Luca A Lotta, Ivonne Sluijs, Isobel D Stewart, Rupal L Shah, Yvonne T van der Schouw, Eleanor Wheeler, Eva Ardanaz, Heiner Boeing, Miren Dorronsoro, Christina C Dahm, Niki Dimou, Douae El-Fatouhi, Paul W Franks, Guy Fagherazzi, Sara Grioni, José María Huerta, Alicia K Heath, Louise Hansen, Mazda Jenab, Paula Jakszyn, Rudolf Kaaks, Tilman Kühn, Kay-Tee Khaw, Nasser Laouali, Giovanna Masala, Peter M Nilsson, Kim Overvad, Anja Olsen, Salvatore Panico, J Ramón Quirós, Olov Rolandsson, Miguel Rodríguez-Barranco, Carlotta Sacerdote, Annemieke M W Spijkerman, Tammy Y N Tong, Rosario Tumino, Konstantinos K Tsilidis, John Danesh, Elio Riboli, Adam S Butterworth, Claudia Langenberg, Nita G Forouhi, Nicholas J Wareham
Published 2020-10-01

Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study

by Aayah Nounu, Rebecca C. Richmond, Isobel D. Stewart, Praveen Surendran, Nicholas J. Wareham, Adam Butterworth, Stephanie J. Weinstein, Demetrius Albanes, John A. Baron, John L. Hopper, Jane C. Figueiredo, Polly A. Newcomb, Noralane M. Lindor, Graham Casey, Elizabeth A. Platz, Loïc Le Marchand, Cornelia M. Ulrich, Christopher I. Li, Fränzel J. B. van Dujinhoven, Andrea Gsur, Peter T. Campbell, Víctor Moreno, Pavel Vodicka, Ludmila Vodickova, Efrat Amitay, Elizabeth Alwers, Jenny Chang-Claude, Lori C. Sakoda, Martha L. Slattery, Robert E. Schoen, Marc J. Gunter, Sergi Castellví-Bel, Hyeong-Rok Kim, Sun-Seog Kweon, Andrew T. Chan, Li Li, Wei Zheng, D. Timothy Bishop, Daniel D. Buchanan, Graham G. Giles, Stephen B. Gruber, Gad Rennert, Zsofia K. Stadler, Tabitha A. Harrison, Yi Lin, Temitope O. Keku, Michael O. Woods, Clemens Schafmayer, Bethany Van Guelpen, Steven Gallinger, Heather Hampel, Sonja I. Berndt, Paul D. P. Pharoah, Annika Lindblom, Alicja Wolk, Anna H. Wu, Emily White, Ulrike Peters, David A. Drew, Dominique Scherer, Justo Lorenzo Bermejo, Hermann Brenner, Michael Hoffmeister, Ann C. Williams, Caroline L. Relton
Published 2021-11-01