Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome

by Marius A. Klein, Klemens Wild, Miglė Kišonaitė, Irmgard Sinning
Published 2024-01-01

High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation

by Miglė Kišonaitė, Klemens Wild, Karine Lapouge, Thomas Ruppert, Irmgard Sinning
Published 2022-01-01

Drosophila photoreceptor cells exploited for the production of eukaryotic membrane proteins: receptors, transporters and channels.

by Valérie Panneels, Ines Kock, Jacomine Krijnse-Locker, Meriem Rezgaoui, Irmgard Sinning
Published 2011-01-01

Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin–ligand-type complexes

by Yasar Luqman Ahmed, Matthias Thoms, Valentin Mitterer, Irmgard Sinning, Ed Hurt
Published 2019-07-01

Targeting of Drosophila rhodopsin requires helix 8 but not the distal C-terminus.

by Ines Kock, Natalia A Bulgakova, Elisabeth Knust, Irmgard Sinning, Valérie Panneels
Published 2009-07-01

Structural basis of Naa20 activity towards a canonical NatB substrate

by Dominik Layer, Jürgen Kopp, Miriam Fontanillo, Maja Köhn, Karine Lapouge, Irmgard Sinning
Published 2021-01-01

Structural basis of HypK regulating N-terminal acetylation by the NatA complex

by Felix Alexander Weyer, Andrea Gumiero, Karine Lapouge, Gert Bange, Jürgen Kopp, Irmgard Sinning
Published 2017-06-01

The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain

by Nikolay Dobrev, Yasar Luqman Ahmed, Anusree Sivadas, Komal Soni, Tamás Fischer, Irmgard Sinning
Published 2021-06-01

MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments

by Klemens Wild, Milan Aleksić, Karine Lapouge, Keven D. Juaire, Dirk Flemming, Stefan Pfeffer, Irmgard Sinning
Published 2020-02-01

Extended N-Terminal Acetyltransferase Naa50 in Filamentous Fungi Adds to Naa50 Diversity

by Jonas Weidenhausen, Jürgen Kopp, Carmen Ruger-Herreros, Frank Stein, Per Haberkant, Karine Lapouge, Irmgard Sinning
Published 2022-09-01

DENR-MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation.

by Yasar Luqman Ahmed, Sibylle Schleich, Jonathan Bohlen, Nicolas Mandel, Bernd Simon, Irmgard Sinning, Aurelio A Teleman
Published 2018-06-01

The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb

by Ying Zhang, Genís Valentín Gesé, Charlotte Conz, Karine Lapouge, Jürgen Kopp, Tina Wölfle, Sabine Rospert, Irmgard Sinning
Published 2020-03-01

Correction: Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome.

by Bebiana Sá-Moura, Markus Kornprobst, Satyavati Kharde, Yasar Luqman Ahmed, Gunter Stier, Ruth Kunze, Irmgard Sinning, Ed Hurt
Published 2020-01-01

Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome.

by Bebiana Sá-Moura, Markus Kornprobst, Satyavati Kharde, Yasar Luqman Ahmed, Gunter Stier, Ruth Kunze, Irmgard Sinning, Ed Hurt
Published 2017-01-01

Structural basis for 5'-ETS recognition by Utp4 at the early stages of ribosome biogenesis.

by Fabiola R Calviño, Markus Kornprobst, Géza Schermann, Fabienne Birkle, Klemens Wild, Tamas Fischer, Ed Hurt, Yasar Luqman Ahmed, Irmgard Sinning
Published 2017-01-01

Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL

by Jeremy Sloan, Jana P. Hakenjos, Michael Gebert, Olga Ermakova, Andrea Gumiero, Gunter Stier, Klemens Wild, Irmgard Sinning, Jan U. Lohmann
Published 2020-05-01

Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex

by Komal Soni, Anusree Sivadas, Attila Horvath, Nikolay Dobrev, Rippei Hayashi, Leo Kiss, Bernd Simon, Klemens Wild, Irmgard Sinning, Tamás Fischer
Published 2023-02-01

The GET insertase exhibits conformational plasticity and induces membrane thinning

by Melanie A. McDowell, Michael Heimes, Giray Enkavi, Ákos Farkas, Daniel Saar, Klemens Wild, Blanche Schwappach, Ilpo Vattulainen, Irmgard Sinning
Published 2023-11-01

The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase

by Valentin Bohl, Nele Merret Hollmann, Tobias Melzer, Panagiotis Katikaridis, Lena Meins, Bernd Simon, Dirk Flemming, Irmgard Sinning, Janosch Hennig, Axel Mogk
Published 2024-04-01

Head-to-tail interactions of the coiled-coil domains regulate ClpB activity and cooperation with Hsp70 in protein disaggregation

by Marta Carroni, Eva Kummer, Yuki Oguchi, Petra Wendler, Daniel K Clare, Irmgard Sinning, Jürgen Kopp, Axel Mogk, Bernd Bukau, Helen R Saibil
Published 2014-04-01