The non-clonality of drug resistance in Beijing-genotype isolates of <it>Mycobacterium tuberculosis </it>from the Western Cape of South Africa

by Van Helden Paul D, Gey van Pittius Nicolaas C, Warren Robin M, Streicher Elizabeth M, Victor Thomas C, Chen Xiaohua, Dobos Karen M, Feng Yicheng, Ioerger Thomas R, Sacchettini James C
Published 2010-11-01

cctbx news

by Grosse-Kunstleve, Ralf W., Zwart, Peter H., Afonine, Pavel V., Ioerger, Thomas R., Adams, Paul D.
Published 2006

On the Use of Intelligent Agents as Partners in Training Systems for Complex Tasks1

by Ioerger, Thomas R., Sims, Joseph, Volz, Richard A., Workman, Judson, Shebilske, Wayne L.
Published 2003

A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide

by Yadon, Adam N., Maharaj, Kashmeel, Adamson, John H., Lai, Yi-Pin, Sacchettini, James C., Ioerger, Thomas R., Rubin, Eric J., Pym, Alexander S.
Published 2017

Global Assessment of Genomic Regions Required for Growth in Mycobacterium tuberculosis

by Zhang, Yanjia Jason, Ioerger, Thomas R., Huttenhower, Curtis, Long, Jarukit E., Sassetti, Christopher M., Sacchettini, James C., Rubin, Eric Joseph
Published 2013

Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment

by Gomez, James E, Kaufmann-Malaga, Benjamin B, Wivagg, Carl N, Kim, Peter B, Silvis, Melanie R, Renedo, Nikolai, Ioerger, Thomas R, Ahmad, Rushdy, Livny, Jonathan, Fishbein, Skye, Sacchettini, James C, Carr, Steven A, Hung, Deborah T
Published 2017

A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis

by Boutte, Cara C, Baer, Christina E, Papavinasasundaram, Kadamba, Liu, Weiru, Chase, Michael R, Meniche, Xavier, Fortune, Sarah M, Sassetti, Christopher M, Ioerger, Thomas R, Rubin, Eric J
Published 2016

High-Throughput Sequencing Enhanced Phage Display Identifies Peptides That Bind Mycobacteria

by Ngubane, Nqobile A. C., Gresh, Lionel, Ioerger, Thomas R., Sacchettini, James C., Zhang, Yanjia J., Rubin, Eric J., Pym, Alexander, Khati, Makobetsa
Published 2014

MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212

by Rosa, Valentina La, Poce, Giovanna, Canseco, Julio Ortiz, Buroni, Silvia, Pasca, Maria Rosalia, Biava, Mariangela, Raju, Ravikiran M., Porretta, Giulio Cesare, Alfonso, Salvatore, Battilocchio, Claudio, Javid, Babak, Sorrentino, Flavia, Ioerger, Thomas R., Sacchettini, James C., Manetti, Fabrizio, Botta, Maurizio, Logu, Alessandro De, Rubin, Eric J., Rossi, Edda De
Published 2019

Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment

by Gomez, James E, Kaufmann-Malaga, Benjamin B, Wivagg, Carl N, Kim, Peter B, Silvis, Melanie R, Renedo, Nikolai, Ioerger, Thomas R, Ahmad, Rushdy, Livny, Jonathan, Fishbein, Skye, Hung, Deborah T, Carr, Steven A
Published 2017

A vitamin B12 transporter in Mycobacterium tuberculosis

by Gopinath, Krishnamoorthy, Venclovas, Česlovas, Ioerger, Thomas R., Sacchettini, James C., McKinney, John D., Mizrahi, Valerie, Warner, Digby F.
Published 2013

Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis

by DeJesus, Michael A., Gerrick, Elias R., Xu, Weizhen, Park, Sae Woong, Long, Jarukit E., Boutte, Cara C., Rubin, Eric J., Schnappinger, Dirk, Ehrt, Sabine, Fortune, Sarah M., Sassetti, Christopher M., Ioerger, Thomas R.
Published 2017

Identification of New Drug Targets and Resistance Mechanisms in Mycobacterium tuberculosis

by Ioerger, Thomas R., O’Malley, Theresa, Liao, Reiling, Guinn, Kristine M., Hickey, Mark J., Mohaideen, Nilofar, Murphy, Kenan C., Boshoff, Helena I. M., Mizrahi, Valerie, Rubin, Eric J., Sassetti, Christopher M., Barry, Clifton E., Sherman, David R., Parish, Tanya, Sacchettini, James C.
Published 2014

TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities

by Carey, Allison F., Rock, Jeremy M., Krieger, Inna V., Chase, Michael R., Fernandez-Suarez, Marta, Gagneux, Sebastien, Sacchettini, James C., Ioerger, Thomas R., Fortune, Sarah M.
Published 2018