Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens

by Lassi Liljeroos, Enrico Malito, Ilaria Ferlenghi, Matthew James Bottomley
Published 2015-01-01

Pneumococcal pili are composed of protofilaments exposing adhesive clusters of Rrg A.

by Markus Hilleringmann, Fabiola Giusti, Barbara C Baudner, Vega Masignani, Antonello Covacci, Rino Rappuoli, Michèle A Barocchi, Ilaria Ferlenghi
Published 2008-03-01

Self-assembling protein nanoparticles and virus like particles correctly display β-barrel from meningococcal factor H-binding protein through genetic fusion.

by Luigia Cappelli, Paolo Cinelli, Fabiola Giusti, Ilaria Ferlenghi, Sabrina Utrio-Lanfaloni, Newton Wahome, Matthew James Bottomley, Domenico Maione, Roberta Cozzi
Published 2022-01-01

An Innovative Pseudotypes-Based Enzyme-Linked Lectin Assay for the Measurement of Functional Anti-Neuraminidase Antibodies.

by Marua Prevato, Roberta Cozzi, Alfredo Pezzicoli, Anna Rita Taddei, Ilaria Ferlenghi, Avishek Nandi, Emanuele Montomoli, Ethan C Settembre, Sylvie Bertholet, Alessandra Bonci, Francois Legay
Published 2015-01-01

Expression and Characterization of Recombinant, Tetrameric and Enzymatically Active Influenza Neuraminidase for the Setup of an Enzyme-Linked Lectin-Based Assay.

by Marua Prevato, Ilaria Ferlenghi, Alessandra Bonci, Yasushi Uematsu, Giulia Anselmi, Fabiola Giusti, Sylvie Bertholet, Francois Legay, John Laird Telford, Ethan C Settembre, Domenico Maione, Roberta Cozzi
Published 2015-01-01

High yield production process for Shigella outer membrane particles.

by Francesco Berlanda Scorza, Anna Maria Colucci, Luana Maggiore, Silvia Sanzone, Omar Rossi, Ilaria Ferlenghi, Isabella Pesce, Mariaelena Caboni, Nathalie Norais, Vito Di Cioccio, Allan Saul, Christiane Gerke
Published 2012-01-01

Moraxella catarrhalis evades neutrophil oxidative stress responses providing a safer niche for nontypeable Haemophilus influenzae

by Sonia Nicchi, Fabiola Giusti, Stefano Carello, Sabrina Utrio Lanfaloni, Simona Tavarini, Elisabetta Frigimelica, Ilaria Ferlenghi, Silvia Rossi Paccani, Marcello Merola, Isabel Delany, Vincenzo Scarlato, Domenico Maione, Cecilia Brettoni
Published 2022-03-01

<i>Neisseria meningitidis</i> Factor H Binding Protein Surface Exposure on <i>Salmonella</i> Typhimurium GMMA Is Critical to Induce an Effective Immune Response against Both Diseas...

by Francesca Necchi, Giuseppe Stefanetti, Renzo Alfini, Elena Palmieri, Martina Carducci, Roberta Di Benedetto, Fabiola Schiavo, Maria Grazia Aruta, Fabiola Giusti, Ilaria Ferlenghi, Yun Shan Goh, Simona Rondini, Francesca Micoli
Published 2021-06-01

Effective Multivalent Oriented Presentation of Meningococcal NadA Antigen Trimers by Self-Assembling Ferritin Nanoparticles

by Daniele Veggi, Lucia Dello Iacono, Enrico Malito, Giulietta Maruggi, Fabiola Giusti, Panchali Goswami, Werner Pansegrau, Sara Marchi, Sara Tomei, Enrico Luzzi, Matthew James Bottomley, Federico Fontani, Ilaria Ferlenghi, Maria Scarselli
Published 2023-03-01

Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus.

by Glen Spraggon, Eric Koesema, Maria Scarselli, Enrico Malito, Massimiliano Biagini, Nathalie Norais, Carla Emolo, Michèle Anne Barocchi, Fabiola Giusti, Markus Hilleringmann, Rino Rappuoli, Scott Lesley, Antonello Covacci, Vega Masignani, Ilaria Ferlenghi
Published 2010-06-01

Stability of Outer Membrane Vesicles-Based Vaccines, Identifying the Most Appropriate Methods to Detect Changes in Vaccine Potency

by Elena Palmieri, Vanessa Arato, Davide Oldrini, Beatrice Ricchetti, Maria Grazia Aruta, Werner Pansegrau, Sara Marchi, Fabiola Giusti, Ilaria Ferlenghi, Omar Rossi, Renzo Alfini, Carlo Giannelli, Gianmarco Gasperini, Francesca Necchi, Francesca Micoli
Published 2021-03-01

Synergistic Protective Activity of Tumor-Specific Epitopes Engineered in Bacterial Outer Membrane Vesicles

by Alberto Grandi, Michele Tomasi, Ilaria Zanella, Luisa Ganfini, Elena Caproni, Laura Fantappiè, Carmela Irene, Luca Frattini, Samine J. Isaac, Enrico König, Francesca Zerbini, Simona Tavarini, Chiara Sammicheli, Fabiola Giusti, Ilaria Ferlenghi, Matteo Parri, Guido Grandi
Published 2017-11-01

FdeC, a Novel Broadly Conserved <named-content content-type="genus-species">Escherichia coli</named-content> Adhesin Eliciting Protection against Urinary Tract Infections

by Barbara Nesta, Glen Spraggon, Christopher Alteri, Danilo Gomes Moriel, Roberto Rosini, Daniele Veggi, Sara Smith, Isabella Bertoldi, Ilaria Pastorello, Ilaria Ferlenghi, Maria Rita Fontana, Gad Frankel, Harry L. T. Mobley, Rino Rappuoli, Mariagrazia Pizza, Laura Serino, Marco Soriani
Published 2012-05-01

Proteome‐minimized outer membrane vesicles from Escherichia coli as a generalized vaccine platform

by Ilaria Zanella, Enrico König, Michele Tomasi, Assunta Gagliardi, Luca Frattini, Laura Fantappiè, Carmela Irene, Francesca Zerbini, Elena Caproni, Samine J. Isaac, Martina Grigolato, Riccardo Corbellari, Silvia Valensin, Ilaria Ferlenghi, Fabiola Giusti, Luca Bini, Yaqoub Ashhab, Alberto Grandi, Guido Grandi
Published 2021-02-01