Structural basis for endoperoxide-forming oxygenases

by Takahiro Mori, Ikuro Abe
Published 2022-06-01

Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis

by Takayoshi Awakawa, Ikuro Abe
Published 2019-07-01

Reconstitution of Polyketide-Derived Meroterpenoid Biosynthetic Pathway in <i>Aspergillus oryzae</i>

by Takayoshi Awakawa, Ikuro Abe
Published 2021-06-01

Oxidative modification of free-standing amino acids by Fe(II)/αKG-dependent oxygenases

by Hui Tao, Ikuro Abe
Published 2023-03-01

Microbial soluble aromatic prenyltransferases for engineered biosynthesis

by He-Ping Chen, Ikuro Abe
Published 2021-06-01

Posttranslational isoprenylation of tryptophan in bacteria

by Masahiro Okada, Tomotoshi Sugita, Ikuro Abe
Published 2017-02-01

Aminoacyl sulfonamide assembly in SB-203208 biosynthesis

by Zhijuan Hu, Takayoshi Awakawa, Zhongjun Ma, Ikuro Abe
Published 2019-01-01

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by 'Entotheonella'.

by Yu Nakashima, Yoko Egami, Miki Kimura, Toshiyuki Wakimoto, Ikuro Abe
Published 2016-01-01

Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI

by Takahiro Mori, Rui Zhai, Richiro Ushimaru, Yudai Matsuda, Ikuro Abe
Published 2021-07-01

Inherent atomic mobility changes in carbocation intermediates during the sesterterpene cyclization cascade

by Hajime Sato, Takaaki Mitsuhashi, Mami Yamazaki, Ikuro Abe, Masanobu Uchiyama
Published 2019-08-01

Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/α-ketoglutarate-dependent oxygenase SptF

by Hui Tao, Takahiro Mori, Heping Chen, Shuang Lyu, Akihito Nonoyama, Shoukou Lee, Ikuro Abe
Published 2022-01-01

Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases

by Takahiro Mori, Lihan Zhang, Takayoshi Awakawa, Shotaro Hoshino, Masahiro Okada, Hiroyuki Morita, Ikuro Abe
Published 2016-03-01

Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis

by Yu Nakashima, Takahiro Mori, Hitomi Nakamura, Takayoshi Awakawa, Shotaro Hoshino, Miki Senda, Toshiya Senda, Ikuro Abe
Published 2018-01-01

Biosynthesis of clinically used antibiotic fusidic acid and identification of two short-chain dehydrogenase/reductases with converse stereoselectivity

by Zhiqin Cao, Shaoyang Li, Jianming Lv, Hao Gao, Guodong Chen, Takayoshi Awakawa, Ikuro Abe, Xinsheng Yao, Dan Hu
Published 2019-03-01

Extensive expansion of the chemical diversity of fusidane-type antibiotics using a stochastic combinational strategy

by Xiaojun Song, Jianming Lv, Zhiqin Cao, Huiyun Huang, Guodong Chen, Takayoshi Awakawa, Dan Hu, Hao Gao, Ikuro Abe, Xinsheng Yao
Published 2021-06-01

Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis

by Jian-Ming Lv, Dan Hu, Hao Gao, Tetsuo Kushiro, Takayoshi Awakawa, Guo-Dong Chen, Chuan-Xi Wang, Ikuro Abe, Xin-Sheng Yao
Published 2017-11-01

Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution

by Takayoshi Awakawa, Takuma Fujioka, Lihan Zhang, Shotaro Hoshino, Zhijuan Hu, Junko Hashimoto, Ikuko Kozone, Haruo Ikeda, Kazuo Shin-Ya, Wen Liu, Ikuro Abe
Published 2018-08-01

Biosynthetic pathway for furanosteroid demethoxyviridin and identification of an unusual pregnane side-chain cleavage

by Gao-Qian Wang, Guo-Dong Chen, Sheng-Ying Qin, Dan Hu, Takayoshi Awakawa, Shao-Yang Li, Jian-Ming Lv, Chuan-Xi Wang, Xin-Sheng Yao, Ikuro Abe, Hao Gao
Published 2018-05-01

Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation

by Yudai Matsuda, Tongxuan Bai, Christopher B. W. Phippen, Christina S. Nødvig, Inge Kjærbølling, Tammi C. Vesth, Mikael R. Andersen, Uffe H. Mortensen, Charlotte H. Gotfredsen, Ikuro Abe, Thomas O. Larsen
Published 2018-07-01

Functional and structural dissection of glycosyltransferases underlying the glycodiversity of wolfberry-derived bioactive ingredients lycibarbarspermidines

by Shao-Yang Li, Gao-Qian Wang, Liang Long, Jia-Ling Gao, Zheng-Qun Zhou, Yong-Heng Wang, Jian-Ming Lv, Guo-Dong Chen, Dan Hu, Ikuro Abe, Hao Gao
Published 2024-05-01