Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model

by Sumit Agarwal, Michael Behring, Hyung-Gyoon Kim, Prachi Bajpai, Balabhadrapatruni V.S.K. Chakravarthi, Nirzari Gupta, Amr Elkholy, Sameer Al Diffalha, Sooryanarayana Varambally, Upender Manne
Published 2020-04-01

Corrigendum to ‘Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model’ [Translational Oncology 13 (2020) 100754]

by Sumit Agarwal, Michael Behring, Hyung-Gyoon Kim, Prachi Bajpai, Balabhadrapatruni V.S.K. Chakravarthi, Nirzari Gupta, Amr Elkholy, Sameer Al Diffalha, Sooryanarayana Varambally, Upender Manne
Published 2021-11-01

Immunophenotype‐associated gene signature in ductal breast tumors varies by receptor subtype, but the expression of individual signature genes remains consistent

by Michael Behring, Yuanfan Ye, Amr Elkholy, Prachi Bajpai, Sumit Agarwal, Hyung‐Gyoon Kim, Akinyemi I. Ojesina, Howard W Wiener, Upender Manne, Sadeep Shrestha, Ana I. Vazquez
Published 2021-08-01

Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma

by Farrukh Afaq, Sumit Agarwal, Prachi Bajpai, Sameer Al Diffalha, Hyung-Gyoon Kim, Shajan Peter, Moh'd Khushman, Subhash C Chauhan, Priyabrata Mukherjee, Sooryanarayana Varambally, Upender Manne
Published 2024-01-01

Molecular disparities in colorectal cancers of White Americans, Alabama African Americans, and Oklahoma American Indians

by Hiroshi Y. Yamada, Chao Xu, Kenneth L. Jones, Philip H. O’Neill, Madka Venkateshwar, Srikanth Chiliveru, Hyung-Gyoon Kim, Mark Doescher, Katherine T. Morris, Upender Manne, Chinthalapally V. Rao
Published 2023-08-01

Comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian Women

by Mansoor Saleh, Darshan Shimoga Chandrashekar, Sayed Shahin, Sumit Agarwal, Hyung-Gyoon Kim, Michael Behring, Asim Jamal Shaikh, Zahir Moloo, Isam-Eldin A Eltoum, Clayton Yates, Sooryanarayana Varambally, Upender Manne
Published 2021-07-01

DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer

by Sumit Agarwal, Farrukh Afaq, Prachi Bajpai, Hyung‐Gyoon Kim, Amr Elkholy, Michael Behring, Darshan Shimoga Chandrashekar, Sameer Al Diffalha, Moh’d Khushman, Shajan P. Sugandha, Sooryanarayana Varambally, Upender Manne
Published 2022-04-01

Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental Therapeutics

by Prachi Bajpai, Nilam Sanjib Banerjee, Dianne W. Moore, Hyung-Gyoon Kim, Farrukh Afaq, Carlo M. Contreras, Martin J. Heslin, Vishnu B. Reddy, Shajan Peter, Sooryanarayana Varambally, Sameer Al Diffalha, Upender Manne
Published 2022-11-01

PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer

by Sumit Agarwal, Balabhadrapatruni V. S. K. Chakravarthi, Michael Behring, Hyung-Gyoon Kim, Darshan S. Chandrashekar, Nirzari Gupta, Prachi Bajpai, Amr Elkholy, Sai A. H. Balasubramanya, Cherlene Hardy, Sameer Al Diffalha, Sooryanarayana Varambally, Upender Manne
Published 2020-03-01

PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression

by Sumit Agarwal, Balabhadrapatruni V.S.K. Chakravarthi, Hyung-Gyoon Kim, Nirzari Gupta, Kevin Hale, Sai Akshaya Hodigere Balasubramanya, Patsy G. Oliver, Dafydd G. Thomas, Isam-Eldin A. Eltoum, Donald J. Buchsbaum, Upender Manne, Sooryanarayana Varambally
Published 2020-07-01

Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models...

by Melissa Davis, Rachel Martini, Lisa Newman, Olivier Elemento, Jason White, Akanksha Verma, Indrani Datta, Indra Adrianto, Yalei Chen, Kevin Gardner, Hyung-Gyoon Kim, Windy D. Colomb, Isam-Eldin Eltoum, Andra R. Frost, William E. Grizzle, Andrea Sboner, Upender Manne, Clayton Yates
Published 2020-05-01

Microbiome diversity in African American, European American, and Egyptian colorectal cancer patients

by Amr Elkholy, Nagavardhini Avuthu, Mohammed Abdalla, Michael Behring, Prachi Bajpai, Hyung-Gyoon Kim, Doaa Header, Reham AH. Abo Elwafa, Hesham Saed, Amira Embaby, Nefertiti El-Nikhely, Sarah Obuya, Mostafa Mohamed, Ahmed Ashour Badawy, Ahmed Nawar, Farrukh Afaq, Laura Q. Rogers, Sejong Bae, James M. Shikany, Lori Brand Bateman, Mona Fouad, Mansoor Saleh, Temesgen Samuel, Sooryanarayana Varambally, Chittibabu Guda, Waleed Arafat, Upender Manne
Published 2023-07-01