Spinocerebellar Ataxias

by Huda Y. Zoghbi
Published 2000-10-01

Solving the puzzle of neurological diseases: an interview with Huda Zoghbi

by Huda Y. Zoghbi
Published 2017-05-01

Loss of Atoh1 from neurons regulating hypoxic and hypercapnic chemoresponses causes neonatal respiratory failure in mice

by Meike E van der Heijden, Huda Y Zoghbi
Published 2018-07-01

Reduction of Purkinje Cell Pathology in SCA1 Transgenic Mice by p53 Deletion

by Mona D. Shahbazian, Harry T. Orr, Huda Y. Zoghbi
Published 2001-12-01

Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice

by Laura Dean Heckman, Maria H Chahrour, Huda Y Zoghbi
Published 2014-06-01

Loss of MeCP2 Function Across Several Neuronal Populations Impairs Breathing Response to Acute Hypoxia

by Christopher S. Ward, Christopher S. Ward, Christopher S. Ward, Teng-Wei Huang, Teng-Wei Huang, Jose A. Herrera, Jose A. Herrera, Rodney C. Samaco, Rodney C. Samaco, Christopher M. McGraw, Christopher M. McGraw, Diana E. Parra, E. Melissa Arvide, Aya Ito-Ishida, Aya Ito-Ishida, Xiangling Meng, Xiangling Meng, Kerstin Ure, Kerstin Ure, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul
Published 2020-10-01

Impaired spatial memory codes in a mouse model of Rett syndrome

by Sara E Kee, Xiang Mou, Huda Y Zoghbi, Daoyun Ji
Published 2018-07-01

Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth

by Tiemo J Klisch, Anna Vainshtein, Akash J Patel, Huda Y Zoghbi
Published 2017-11-01

The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development.

by Neha Bhat, Jeehye Park, Huda Y Zoghbi, J Simon C Arthur, Kenneth S Zaret
Published 2016-01-01

Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.

by Juan Crespo-Barreto, John D Fryer, Chad A Shaw, Harry T Orr, Huda Y Zoghbi
Published 2010-07-01

Genetic modifiers of MeCP2 function in Drosophila.

by Holly N Cukier, Alma M Perez, Ann L Collins, Zhaolan Zhou, Huda Y Zoghbi, Juan Botas
Published 2008-09-01

Motor neuron degeneration correlates with respiratory dysfunction in SCA1

by James P. Orengo, Meike E. van der Heijden, Shuang Hao, Jianrong Tang, Harry T. Orr, Huda Y. Zoghbi
Published 2018-02-01

Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model

by James P. Orengo, Larissa Nitschke, Meike E. van der Heijden, Nicholas A. Ciaburri, Harry T. Orr, Huda Y. Zoghbi
Published 2022-04-01

Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations

by Ayush T. Raman, Amy E. Pohodich, Ying-Wooi Wan, Hari Krishna Yalamanchili, William E. Lowry, Huda Y. Zoghbi, Zhandong Liu
Published 2018-08-01

MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function

by Sameer S Bajikar, Ashley G Anderson, Jian Zhou, Mark A Durham, Alexander J Trostle, Ying-Wooi Wan, Zhandong Liu, Huda Y Zoghbi
Published 2023-02-01

Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery.

by Juliette J Kahle, George P Souroullas, Peng Yu, Fabian Zohren, Yoontae Lee, Chad A Shaw, Huda Y Zoghbi, Margaret A Goodell
Published 2013-03-01

Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.

by Kei Watase, Jennifer R Gatchel, Yaling Sun, Effat Emamian, Richard Atkinson, Ronald Richman, Hidehiro Mizusawa, Harry T Orr, Chad Shaw, Huda Y Zoghbi
Published 2007-05-01

Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau

by Maxime WC Rousseaux, Jean-Pierre Revelli, Gabriel E Vázquez-Vélez, Ji-Yoen Kim, Evelyn Craigen, Kristyn Gonzales, Jaclyn Beckinghausen, Huda Y Zoghbi
Published 2018-06-01

Atoh1-dependent rhombic lip neurons are required for temporal delay between independent respiratory oscillators in embryonic mice

by Srinivasan Tupal, Wei-Hsiang Huang, Maria Cristina D Picardo, Guang-Yi Ling, Christopher A Del Negro, Huda Y Zoghbi, Paul A Gray
Published 2014-05-01

Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity

by Amy E Pohodich, Hari Yalamanchili, Ayush T Raman, Ying-Wooi Wan, Michael Gundry, Shuang Hao, Haijing Jin, Jianrong Tang, Zhandong Liu, Huda Y Zoghbi
Published 2018-03-01