Molecular dynamics of G6PD variants from sub-Saharan Africa

by Jorge Batista da Rocha, Houcemeddine Othman, Scott Hazelhurst
Published 2022-07-01

Single Nucleotide Polymorphism Induces Divergent Dynamic Patterns in CYP3A5: A Microsecond Scale Biomolecular Simulation of Variants Identified in Sub-Saharan African Populations

by Houcemeddine Othman, Jorge E. B. da Rocha, Scott Hazelhurst
Published 2021-07-01

SWAAT Bioinformatics Workflow for Protein Structure-Based Annotation of ADME Gene Variants

by Houcemeddine Othman, Sherlyn Jemimah, Jorge Emanuel Batista da Rocha
Published 2022-02-01

SARS-CoV-2 Spike Protein Unlikely to Bind to Integrins via the Arg-Gly-Asp (RGD) Motif of the Receptor Binding Domain: Evidence From Structural Analysis and Microscale Accelerated...

by Houcemeddine Othman, Houcemeddine Othman, Haifa Ben Messaoud, Oussema Khamessi, Hazem Ben-Mabrouk, Kais Ghedira, Avani Bharuthram, Florette Treurnicht, Ikechukwu Achilonu, Yasien Sayed, Najet Srairi-Abid
Published 2022-02-01

Characterization of Kbot21 Reveals Novel Side Chain Interactions of Scorpion Toxins Inhibiting Voltage-Gated Potassium Channels.

by Rym ElFessi-Magouri, Steve Peigneur, Houcemeddine Othman, Najet Srairi-Abid, Mohamed ElAyeb, Jan Tytgat, Riadh Kharrat
Published 2015-01-01

In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect

by Sondes Haddad-Boubaker, Houcemeddine Othman, Rabeb Touati, Kaouther Ayouni, Marwa Lakhal, Imen Ben Mustapha, Kais Ghedira, Maher Kharrat, Henda Triki
Published 2021-03-01

Antimicrobial resistance genes, virulence markers and prophage sequences in Salmonella enterica serovar Enteritidis isolated in Tunisia using whole genome sequencing

by Boutheina Ksibi, Sonia Ktari, Kais Ghedira, Houcemeddine Othman, Sonda Maalej, Basma Mnif, Laetitia Fabre, Faouzia Rhimi, Simon Le Hello, Adnene Hammami
Published 2022-01-01

AaTs-1: A Tetrapeptide from <i>Androctonus australis</i> Scorpion Venom, Inhibiting U87 Glioblastoma Cells Proliferation by p53 and FPRL-1 Up-Regulations

by Dorra Aissaoui-Zid, Mohamed-Chiheb Saada, Wassim Moslah, Marie Potier-Cartereau, Aude Lemettre, Houcemeddine Othman, Marc Gaysinski, Zaineb Abdelkafi-Koubaa, Soumaya Souid, Naziha Marrakchi, Christophe Vandier, Khadija Essafi-Benkhadir, Najet Srairi-Abid
Published 2021-12-01

Case Report: Identification of Novel Variants in ERCC4 and DDB2 Genes in Two Tunisian Patients With Atypical Xeroderma Pigmentosum Phenotype

by Imen Nabouli, Asma Chikhaoui, Houcemeddine Othman, Sahar Elouej, Sahar Elouej, Meriem Jones, Meriem Jones, Arnaud Lagarde, Meriem Ben Rekaya, Olfa Messaoud, Mohamed Zghal, Valerie Delague, Nicolas Levy, Nicolas Levy, Annachiara De Sandre-Giovannoli, Annachiara De Sandre-Giovannoli, Sonia Abdelhak, Houda Yacoub-Youssef
Published 2021-05-01

A Rare <em>MSH2</em> Variant as a Candidate Marker for Lynch Syndrome II Screening in Tunisia: A Case of Diffuse Gastric Carcinoma

by Maria Kabbage, Jihenne Ben Aissa-Haj, Houcemeddine Othman, Amira Jaballah-Gabteni, Sarra Laarayedh, Sahar Elouej, Mouna Medhioub, Haifa Tounsi Kettiti, Amal Khsiba, Moufida Mahmoudi, Houda BelFekih, Afifa Maaloul, Hassen Touinsi, Lamine Hamzaoui, Emna Chelbi, Sonia Abdelhak, Mohamed Samir Boubaker, Mohamed Mousaddak Azzouz
Published 2022-07-01

Identification of Novel BRCA1 and RAD50 Mutations Associated With Breast Cancer Predisposition in Tunisian Patients

by Najah Mighri, Yosr Hamdi, Maroua Boujemaa, Houcemeddine Othman, Sonia Ben Nasr, Sonia Ben Nasr, Houda El Benna, Nesrine Mejri, Nesrine Mejri, Soumaya Labidi, Soumaya Labidi, Jihen Ayari, Jihen Ayari, Olfa Jaidene, Hanen Bouaziz, Mariem Ben Rekaya, Ridha M’rad, Abderrazek Haddaoui, Khaled Rahal, Hamouda Boussen, Hamouda Boussen, Samir Boubaker, Sonia Abdelhak
Published 2020-11-01

The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations

by Jorge E. B. da Rocha, Jorge E. B. da Rocha, Houcemeddine Othman, Gerrit Botha, Laura Cottino, Laura Cottino, David Twesigomwe, David Twesigomwe, Samah Ahmed, Britt I. Drögemöller, Faisal M. Fadlelmola, Philip Machanick, Mamana Mbiyavanga, Sumir Panji, Galen E. B. Wright, Galen E. B. Wright, Clement Adebamowo, Clement Adebamowo, Mogomotsi Matshaba, Mogomotsi Matshaba, Michéle Ramsay, Michéle Ramsay, Gustave Simo, Martin C. Simuunza, Caroline T. Tiemessen, Sandra Baldwin, Mathias Chiano, Charles Cox, Annette S. Gross, Pamela Thomas, Francisco-Javier Gamo, Scott Hazelhurst, Scott Hazelhurst
Published 2021-04-01

African Genomic Medicine Portal: A Web Portal for Biomedical Applications

by Houcemeddine Othman, Lyndon Zass, Jorge E. B. da Rocha, Fouzia Radouani, Chaimae Samtal, Ichrak Benamri, Judit Kumuthini, Yasmina J. Fakim, Yosr Hamdi, Nessrine Mezzi, Maroua Boujemaa, Chiamaka Jessica Okeke, Maureen B. Tendwa, Kholoud Sanak, Melek Chaouch, Sumir Panji, Rym Kefi, Reem M. Sallam, Anisah W. Ghoorah, Lilia Romdhane, Anmol Kiran, Ayton P. Meintjes, Perceval Maturure, Haifa Jmel, Ayoub Ksouri, Maryame Azzouzi, Mohammed A. Farahat, Samah Ahmed, Rania Sibira, Michael E. E. Turkson, Alfred Ssekagiri, Ziyaad Parker, Faisal M. Fadlelmola, Kais Ghedira, Nicola Mulder, Samar Kamal Kassim
Published 2022-02-01