T-bet represses collagen-induced arthritis by suppressing Th17 lineage commitment through inhibition of RORγt expression and function

by Masaru Shimizu, Yuya Kondo, Reona Tanimura, Kotona Furuyama, Masahiro Yokosawa, Hiromitsu Asashima, Hiroto Tsuboi, Isao Matsumoto, Takayuki Sumida
Published 2021-08-01

Specific Increase in Joint Neutrophil Extracellular Traps and Its Relation to Interleukin 6 in Autoimmune Arthritis

by Ayako Ohyama, Atsumu Osada, Hoshimi Kawaguchi, Izumi Kurata, Taihei Nishiyama, Tamaki Iwai, Akihito Ishigami, Yuya Kondo, Hiroto Tsuboi, Takayuki Sumida, Isao Matsumoto
Published 2021-07-01

Effect of climatic environment on immunological features of rheumatoid arthritis

by Yuya Kondo, Saori Abe, Hirofumi Toko, Tomoya Hirota, Hiroyuki Takahashi, Masaru Shimizu, Hisashi Noma, Hiroto Tsuboi, Isao Matsumoto, Toshiro Inaba, Takayuki Sumida
Published 2023-01-01

Activation mechanisms of monocytes/macrophages in adult-onset Still disease

by Hiroto Tsuboi, Seiji Segawa, Mizuki Yagishita, Hirofumi Toko, Fumika Honda, Ayako Kitada, Haruka Miki, Ayako Ohyama, Shinya Hagiwara, Yuya Kondo, Isao Matsumoto, Takayuki Sumida
Published 2022-08-01

Ganglionic Acetylcholine Receptor Antibodies and Autonomic Dysfunction in Autoimmune Rheumatic Diseases

by Michie Imamura, Akihiro Mukaino, Koutaro Takamatsu, Hiroto Tsuboi, Osamu Higuchi, Hideki Nakamura, Saori Abe, Yukio Ando, Hidenori Matsuo, Tadashi Nakamura, Takayuki Sumida, Atsushi Kawakami, Shunya Nakane
Published 2020-02-01

A case of refractory Kimura disease with a buccal bulky mass successfully treated with low-dose cyclosporine A: Report and review of the literature

by Haruka Miki, Hiroto Tsuboi, Shunta Kaneko, Hiroyuki Takahashi, Masahiro Yokosawa, Hiromitsu Asashima, Tomoya Hirota, Shinya Hagiwara, Naoto Umeda, Yuya Kondo, Bungo Nishimura, Masato Sugano, Isao Matsumoto, Takayuki Sumida
Published 2016-04-01

Identification of novel biomarker as citrullinated inter-alpha-trypsin inhibitor heavy chain 4, specifically increased in sera with experimental and rheumatoid arthritis

by Hoshimi Kawaguchi, Isao Matsumoto, Atsumu Osada, Izumi Kurata, Hiroshi Ebe, Yuki Tanaka, Asuka Inoue, Naoto Umeda, Yuya Kondo, Hiroto Tsuboi, Yasuhiro Shinkai, Yoshito Kumagai, Akihito Ishigami, Takayuki Sumida
Published 2018-04-01

Functional Analysis of Dendritic Cells Generated from T-iPSCs from CD4+ T Cell Clones of Sjögren's Syndrome

by Mana Iizuka-Koga, Hiromitsu Asashima, Miki Ando, Chen-Yi Lai, Shinji Mochizuki, Mahito Nakanishi, Toshinobu Nishimura, Hiroto Tsuboi, Tomoya Hirota, Hiroyuki Takahashi, Isao Matsumoto, Makoto Otsu, Takayuki Sumida
Published 2017-05-01

Pathogenic roles and therapeutic potential of the CCL8–CCR8 axis in a murine model of IgG4-related sialadenitis

by Fumika Honda, Hiroto Tsuboi, Yuko Ono, Saori Abe, Hiroyuki Takahashi, Kiyoaki Ito, Kazunori Yamada, Mitsuhiro Kawano, Yuya Kondo, Kenichi Asano, Masato Tanaka, Marie Malissen, Bernard Malissen, Isao Matsumoto, Takayuki Sumida
Published 2021-08-01

Clinical features and serum cytokine profiles of elderly-onset adult-onset Still’s disease

by Mizuki Yagishita, Hiroto Tsuboi, Yuki Kuroda, Tomonori Sawabe, Akira Kawashima, Fumina Kawashima, Nana Uematsu, Ryota Sato, Taihei Nishiyama, Mayu Terasaki, Hirofumi Toko, Fumika Honda, Ayako Ohyama, Saori Abe, Ayako Kitada, Haruka Miki, Shinya Hagiwara, Yuya Kondo, Takayuki Sumida, Isao Matsumoto
Published 2022-12-01

Decreased Expression of Innate Immunity-Related Genes in Peripheral Blood Mononuclear Cells from Patients with IgG4-Related Disease.

by Akio Nakajima, Yasufumi Masaki, Takuji Nakamura, Takafumi Kawanami, Yasuhito Ishigaki, Tsutomu Takegami, Mitsuhiro Kawano, Kazunori Yamada, Norifumi Tsukamoto, Shoko Matsui, Takako Saeki, Kazuichi Okazaki, Terumi Kamisawa, Taiichiro Miyashita, Yoshihiro Yakushijin, Keita Fujikawa, Motohisa Yamamoto, Hideaki Hamano, Tomoki Origuchi, Shintaro Hirata, Hiroto Tsuboi, Takayuki Sumida, Hisanori Morimoto, Tomomi Sato, Haruka Iwao, Miyuki Miki, Tomoyuki Sakai, Yoshimasa Fujita, Masao Tanaka, Toshihiro Fukushima, Toshiro Okazaki, Hisanori Umehara
Published 2015-01-01