Mechanisms of Fibroblast Activation and Myocardial Fibrosis: Lessons Learned from FB-Specific Conditional Mouse Models

by Prachi Umbarkar, Suma Ejantkar, Sultan Tousif, Hind Lal
Published 2021-09-01

A Pharmacovigilance Study of Hydroxychloroquine Cardiac Safety Profile: Potential Implication in COVID-19 Mitigation

by Anand Prakash Singh, Sultan Tousif, Prachi Umbarkar, Hind Lal
Published 2020-06-01

Deletion of Cardiomyocyte Glycogen Synthase Kinase-3 Beta (GSK-3β) Improves Systemic Glucose Tolerance with Maintained Heart Function in Established Obesity

by Manisha Gupte, Prachi Umbarkar, Anand Prakash Singh, Qinkun Zhang, Sultan Tousif, Hind Lal
Published 2020-04-01

Isoform-Specific Role of GSK-3 in High Fat Diet Induced Obesity and Glucose Intolerance

by Manisha Gupte, Sultan Tousif, Jacob J. Lemon, Angelica Toro Cora, Prachi Umbarkar, Hind Lal
Published 2022-02-01

Bone marrow‐fibroblast progenitor cell‐derived small extracellular vesicles promote cardiac fibrosis via miR‐21‐5p and integrin subunit αV signalling

by Prabhat Ranjan, Roshan Kumar Dutta, Karen Colin, Jing Li, Qinkun Zhang, Hind Lal, Gangjian Qin, Suresh Kumar Verma
Published 2024-06-01

Metabolic labeling of cardiomyocyte‐derived small extracellular‐vesicle (sEV) miRNAs identifies miR‐208a in cardiac regulation of lung gene expression

by Chaoshan Han, Junjie Yang, Eric Zhang, Ying Jiang, Aijun Qiao, Yipeng Du, Qinkun Zhang, Junqing An, Jiacheng Sun, Meimei Wang, Thanh Nguyen, Hind Lal, Prasanna Krishnamurthy, Jianyi Zhang, Gangjian Qin
Published 2022-10-01

Cardiomyocyte SMAD4-Dependent TGF-β Signaling is Essential to Maintain Adult Heart Homeostasis

by Prachi Umbarkar, PhD, Anand P. Singh, PhD, Manisha Gupte, PhD, Vipin K. Verma, PhD, Cristi L. Galindo, PhD, Yuanjun Guo, MD, Qinkun Zhang, MD, James W. McNamara, PhD, Thomas Force, MD, Hind Lal, PhD
Published 2019-02-01

The BDNF rs6265 Polymorphism is a Modifier of Cardiomyocyte Contractility and Dilated Cardiomyopathy

by Frank J. Raucci, Anand Prakash Singh, Jonathan Soslow, Larry W. Markham, Lin Zhong, Wejdan Aljafar, Natasja Lessiohadi, Cassandra P. Awgulewitsch, Prachi Umbarkar, Qinkun Zhang, Presley L. Cannon, Maciej Buchowski, Joseph T. Roland, Erica J. Carrier, William B. Burnette, Antonis K. Hatzopoulos, Hind Lal, Cristi L. Galindo
Published 2020-10-01

Sustained Increases in Cardiomyocyte Protein O‐Linked β‐N‐Acetylglucosamine Levels Lead to Cardiac Hypertrophy and Reduced Mitochondrial Function Without Systolic Contractile Impai...

by Chae‐Myeong Ha, Sayan Bakshi, Manoja K. Brahma, Luke A. Potter, Samuel F. Chang, Zhihuan Sun, Gloria A. Benavides, Lihao He, Prachi Umbarkar, Luyun Zou, Samuel Curfman, Sini Sunny, Andrew J. Paterson, Namakkal‐Soorappan Rajasekaran, Jarrod W. Barnes, Jianhua Zhang, Hind Lal, Min Xie, Victor M. Darley‐Usmar, John C. Chatham, Adam R. Wende
Published 2023-10-01

Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

by Pu Qin, Pelin Arabacilar, Roberta E. Bernard, Weike Bao, Alan R. Olzinski, Yuanjun Guo, Hind Lal, Stephen H. Eisennagel, Michael C. Platchek, Wensheng Xie, Julius del Rosario, Mohamad Nayal, Quinn Lu, Theresa Roethke, Christine G. Schnackenberg, Fe Wright, Michael P. Quaile, Wendy S. Halsey, Ashley M. Hughes, Ganesh M. Sathe, George P. Livi, Robert B. Kirkpatrick, Xiaoyan A. Qu, Deepak K. Rajpal, Maria Faelth Savitski, Marcus Bantscheff, Gerard Joberty, Giovanna Bergamini, Thomas L. Force, Gregory J. Gatto, Erding Hu, Robert N. Willette
Published 2017-05-01