Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages

by Hannah S. Eisfeld, Alexander Simonis, Sandra Winter, Jason Chhen, Luisa J. Ströh, Thomas Krey, Manuel Koch, Sebastian J. Theobald, Jan Rybniker
Published 2021-10-01

Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages

by Sebastian J. Theobald, Jessica Gräb, Melanie Fritsch, Isabelle Suárez, Hannah S. Eisfeld, Sandra Winter, Maximilian Koch, Christoph Hölscher, Manolis Pasparakis, Hamid Kashkar, Jan Rybniker
Published 2021-10-01

Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19

by Sebastian J Theobald, Alexander Simonis, Theodoros Georgomanolis, Christoph Kreer, Matthias Zehner, Hannah S Eisfeld, Marie‐Christine Albert, Jason Chhen, Susanne Motameny, Florian Erger, Julia Fischer, Jakob J Malin, Jessica Gräb, Sandra Winter, Andromachi Pouikli, Friederike David, Boris Böll, Philipp Koehler, Kanika Vanshylla, Henning Gruell, Isabelle Suárez, Michael Hallek, Gerd Fätkenheuer, Norma Jung, Oliver A Cornely, Clara Lehmann, Peter Tessarz, Janine Altmüller, Peter Nürnberg, Hamid Kashkar, Florian Klein, Manuel Koch, Jan Rybniker
Published 2021-08-01