Pharmacogenetic landscape of pain management variants among Mediterranean populations

by Haifa Jmel, Haifa Jmel, Haifa Jmel, Wided Boukhalfa, Wided Boukhalfa, Wided Boukhalfa, Wided Boukhalfa, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Roua Ouled Seghaier, Hamza Dallali, Hamza Dallali, Hamza Dallali, Rym Kefi, Rym Kefi, Rym Kefi
Published 2024-05-01

Decoding the genetic relationship between Alzheimer’s disease and type 2 diabetes: potential risk variants and future direction for North Africa

by Wided Boukhalfa, Wided Boukhalfa, Wided Boukhalfa, Haifa Jmel, Haifa Jmel, Nadia Kheriji, Nadia Kheriji, Nadia Kheriji, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Hamza Dallali, Hamza Dallali, Mariem Hechmi, Mariem Hechmi, Rym Kefi, Rym Kefi
Published 2023-06-01

A map of copy number variations in the Tunisian population: a valuable tool for medical genomics in North Africa

by Lilia Romdhane, Nessrine Mezzi, Hamza Dallali, Olfa Messaoud, Jingxuan Shan, Khalid A. Fakhro, Rym Kefi, Lotfi Chouchane, Sonia Abdelhak
Published 2021-01-01

The first exome wide association study in Tunisia: identification of candidate loci and pathways with biological relevance for type 2 diabetes

by Hamza Dallali, Hamza Dallali, Hamza Dallali, Wided Boukhalfa, Wided Boukhalfa, Wided Boukhalfa, Nadia Kheriji, Nadia Kheriji, Nadia Kheriji, Meriem Fassatoui, Haifa Jmel, Haifa Jmel, Haifa Jmel, Meriem Hechmi, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Mariem Gharbi, Mariem Gharbi, Mariem Gharbi, Wafa Kammoun, Mehdi Mrad, Marouen Taoueb, Asma Krir, Hajer Trabelsi, Afef Bahlous, Henda Jamoussi, Olfa Messaoud, Olfa Messaoud, Abdelmajid Abid, Rym Kefi, Rym Kefi, Rym Kefi
Published 2023-12-01

Using KASP technique to screen LRRK2 G2019S mutation in a large Tunisian cohort

by Zied Landoulsi, Sawssan Benromdhan, Mouna Ben Djebara, Mariem Damak, Hamza Dallali, Rym Kefi, Sonia Abdelhak, Amina Gargouri-Berrechid, Chokri Mhiri, Riadh Gouider
Published 2017-07-01

Association of HNF1A gene variants and haplotypes with metabolic syndrome: a case–control study in the Tunisian population and a meta-analysis

by Hamza Dallali, Meriem Hechmi, Imane Morjane, Sahar Elouej, Haifa Jmel, Yosra Ben Halima, Abdelmajid Abid, Afef Bahlous, Abdelhamid Barakat, Henda Jamoussi, Sonia Abdelhak, Rym Kefi
Published 2022-02-01

Cytogenetic and molecular diagnosis of Fanconi anemia revealed two hidden phenotypes: Disorder of sex development and cerebro‐oculo‐facio‐skeletal syndrome

by Abir Ben Haj Ali, Ahlem Amouri, Marwa Sayeb, Saloua Makni, Wajih Hammami, Chokri Naouali, Hamza Dallali, Lilia Romdhane, Anu Bashamboo, Kenneth McElreavey, Sonia Abdelhak, Olfa Messaoud
Published 2019-07-01

Expanding the clinical phenotype associated with NIPAL4 mutation: Study of a Tunisian consanguineous family with erythrokeratodermia variabilis-Like Autosomal Recessive Congenital...

by Cherine Charfeddine, Nadia Laroussi, Rahma Mkaouar, Raja Jouini, Olfa Khayat, Aladin Redissi, Amor Mosbah, Hamza Dallali, Achraf Chedly Debbiche, Anissa Zaouak, Sami Fenniche, Sonia Abdelhak, Houda Hammami-Ghorbel
Published 2021-01-01

Expanding the clinical phenotype associated with NIPAL4 mutation: Study of a Tunisian consanguineous family with erythrokeratodermia variabilis—Like Autosomal Recessive Congenital...

by Cherine Charfeddine, Nadia Laroussi, Rahma Mkaouar, Raja Jouini, Olfa Khayat, Aladin Redissi, Amor Mosbah, Hamza Dallali, Achraf Chedly Debbiche, Anissa Zaouak, Sami Fenniche, Sonia Abdelhak, Houda Hammami-Ghorbel
Published 2021-01-01

Clinical and Genetic Heterogeneity in Six Tunisian Families With Horizontal Gaze Palsy With Progressive Scoliosis: A Retrospective Study of 13 Cases

by Sami Bouchoucha, Sami Bouchoucha, Asma Chikhaoui, Dorra Najjar, Hamza Dallali, Maleke Khammessi, Sonia Abdelhak, Nabil Nessibe, Mohammad Shboul, Susanne G. Kircher, Ali Al Kaissi, Ali Al Kaissi, Houda Yacoub-Youssef
Published 2020-04-01

Expanding the genetic spectrum of mitochondrial diseases in Tunisia: novel variants revealed by whole-exome sequencing

by Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Meriem Hechmi, Meriem Hechmi, Abir Zioudi, Abir Zioudi, Abir Zioudi, Hamza Dallali, Hamza Dallali, Nadia Kheriji, Nadia Kheriji, Nadia Kheriji, Majida Charif, Morgane Le Mao, Said Galai, Said Galai, Lilia Kraoua, Lilia Kraoua, Ilhem Ben Youssef-Turki, Ilhem Ben Youssef-Turki, Ilhem Ben Youssef-Turki, Ichraf Kraoua, Ichraf Kraoua, Ichraf Kraoua, Guy Lenaers, Guy Lenaers, Rym Kefi, Rym Kefi
Published 2024-01-01

Pharmacogenetic landscape of Metabolic Syndrome components drug response in Tunisia and comparison with worldwide populations.

by Haifa Jmel, Lilia Romdhane, Yosra Ben Halima, Meriem Hechmi, Chokri Naouali, Hamza Dallali, Yosr Hamdi, Jingxuan Shan, Abdelmajid Abid, Henda Jamoussi, Sameh Trabelsi, Lotfi Chouchane, Donata Luiselli, Sonia Abdelhak, Rym Kefi
Published 2018-01-01

Multiallelic Rare Variants in BBS Genes Support an Oligogenic Ciliopathy in a Non-obese Juvenile-Onset Syndromic Diabetic Patient: A Case Report

by Hamza Dallali, Nadia Kheriji, Wafa Kammoun, Mehdi Mrad, Manel Soltani, Hajer Trabelsi, Walid Hamdi, Afef Bahlous, Melika Ben Ahmed, Faten Mahjoub, Henda Jamoussi, Henda Jamoussi, Sonia Abdelhak, Sonia Abdelhak, Rym Kefi, Rym Kefi
Published 2021-10-01

Germline copy number variations in BRCA1/2 negative families: Role in the molecular etiology of hereditary breast cancer in Tunisia.

by Maroua Boujemaa, Yosr Hamdi, Nesrine Mejri, Lilia Romdhane, Kais Ghedira, Hanen Bouaziz, Houda El Benna, Soumaya Labidi, Hamza Dallali, Olfa Jaidane, Sonia Ben Nasr, Abderrazek Haddaoui, Khaled Rahal, Sonia Abdelhak, Hamouda Boussen, Mohamed Samir Boubaker
Published 2021-01-01

Identification of novel pathogenic MSH2 mutation and new DNA repair genes variants: investigation of a Tunisian Lynch syndrome family with discordant twins

by Amira Jaballah-Gabteni, Haifa Tounsi, Maria Kabbage, Yosr Hamdi, Sahar Elouej, Ines Ben Ayed, Mouna Medhioub, Moufida Mahmoudi, Hamza Dallali, Hamza Yaiche, Nadia Ben Jemii, Afifa Maaloul, Najla Mezghani, Sonia Abdelhak, Lamine Hamzaoui, Mousaddak Azzouz, Samir Boubaker
Published 2019-06-01

Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health

by Rahma Mkaouar, Zied Riahi, Jihene Marrakchi, Jihene Marrakchi, Nessrine Mezzi, Nessrine Mezzi, Lilia Romdhane, Lilia Romdhane, Maroua Boujemaa, Hamza Dallali, Hamza Dallali, Marwa Sayeb, Saida Lahbib, Hager Jaouadi, Hager Jaouadi, Hela Boudabbous, Hela Boudabbous, Hela Boudabbous, Lotfi Zekri, Lotfi Zekri, Mariem Chargui, Olfa Messaoud, Meriem Elyounsi, Meriem Elyounsi, Ichraf Kraoua, Ichraf Kraoua, Anissa Zaouak, Ilhem Turki, Ilhem Turki, Mourad Mokni, Sophie Boucher, Sophie Boucher, Christine Petit, Christine Petit, Fabrice Giraudet, Fabrice Giraudet, Chiraz Mbarek, Ghazi Besbes, Soumeyya Halayem, Soumeyya Halayem, Rim Zainine, Rim Zainine, Hamida Turki, Amel Tounsi, Crystel Bonnet, Ridha Mrad, Ridha Mrad, Sonia Abdelhak, Mediha Trabelsi, Mediha Trabelsi, Cherine Charfeddine
Published 2024-04-01

Alpha-mannosidosis in Tunisian consanguineous families: Potential involvement of variants in GHR and SLC19A3 genes in the variable expressivity of cognitive impairment.

by Rahma Mkaouar, Zied Riahi, Cherine Charfeddine, Imen Chelly, Hela Boudabbous, Hamza Dallali, Crystel Bonnet, Meriem Hechmi, Soumeya Bekri, Nadia Zitouna, Lotfi Zekri, Amel Tounsi, Rym Kefi, Jihene Marrakchi, Olfa Messaoud, Ichraf Kraoua, Sonia Maalej, Ilhem Turki Ben Youssef, Ahlem Ben Hmid, Fabrice Giraudet, Sami Bouchoucha, Neji Tebib, Ghazi Besbes, Christine Petit, Ridha Mrad, Sonia Abdelhak, Mediha Trabelsi
Published 2021-01-01

Whole-exome sequencing reveals novel variants of monogenic diabetes in Tunisia: impact on diagnosis and healthcare management

by Nadia Kheriji, Nadia Kheriji, Nadia Kheriji, Hamza Dallali, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Ismail Gouiza, Meriem Hechmi, Faten Mahjoub, Faten Mahjoub, Faten Mahjoub, Mehdi Mrad, Mehdi Mrad, Mehdi Mrad, Asma Krir, Manel Soltani, Hajer Trabelsi, Walid Hamdi, Afef Bahlous, Afef Bahlous, Melika Ben Ahmed, Melika Ben Ahmed, Henda Jamoussi, Henda Jamoussi, Henda Jamoussi, Rym Kefi, Rym Kefi
Published 2023-12-01

Corrigendum: Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health

by Rahma Mkaouar, Zied Riahi, Jihene Marrakchi, Jihene Marrakchi, Nessrine Mezzi, Nessrine Mezzi, Lilia Romdhane, Lilia Romdhane, Maroua Boujemaa, Hamza Dallali, Marwa Sayeb, Saida Lahbib, Hajer Jaouadi, Hajer Jaouadi, Hela Boudabbous, Hela Boudabbous, Hela Boudabbous, Lotfi Zekri, Lotfi Zekri, Mariem Chargui, Olfa Messaoud, Meriem Elyounsi, Meriem Elyounsi, Ichraf Kraoua, Ichraf Kraoua, Anissa Zaouak, Ilhem Turki, Ilhem Turki, Mourad Mokni, Sophie Boucher, Sophie Boucher, Christine Petit, Christine Petit, Fabrice Giraudet, Fabrice Giraudet, Fabrice Giraudet, Chiraz Mbarek, Ghazi Besbes, Soumeyya Halayem, Soumeyya Halayem, Rim Zainine, Rim Zainine, Hamida Turki, Amel Tounsi, CRYSTEL Bonnet, Ridha Mrad, Ridha Mrad, Sonia Abdelhak, Mediha Trabelsi, Mediha Trabelsi, Cherine Charfeddine, Cherine Charfeddine
Published 2024-06-01