Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia

by Ware J.S., Wain L.V., Channavajjhala S.K., Jackson V.E., Edwards E., Lu R., Siew K., Jia W., Shrine N., Kinnear S., Jalland M., Henry A.P., Clayton J., O'Shaughnessy K.M., Tobin M.D., Schuster V.L., Cook S., Hall I.P., Glover M.
Published 2019

Detection of mutations in KLHL3 and CUL3 in families with fhht (familial hyperkalaemic hypertension or gordon's syndrome)

by Glover M., Ware J.S., Henry A., Wolley M., Walsh R., Wain L.V., Xu S., Hoff W.G.V., Tobin M.D., Hall I.P., Cook S., Gordon R.D., Stowasser M., O'shaughnessy K.M.
Published 2019

Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways

by Kheirallah, AK, de Moor, CH, Faiz, A, Sayers, I, Hall, IP
Published 2017

Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function

by Yang, T.Z., Jackson, V.E., Smith, A.V., Chen, H., Bartz, T.M., Sitlani, C.M., Psaty, B.M., Gharib, S.A., O'Connor, G.T., Dupuis, J., Xu, J.Y., Lohman, K., Liu, Y.M., Kritchevsky, S.B., Cassano, P.A., Flexeder, C., Gieger, C., Karrasch, S., Peters, A., Schulz, H., Harris, S.E., Starr, J.M., Deary, I.J., Manichaikul, A., Oelsner, E.C., Barr, R.G., Taylor, K.D., Rich, S.S., Bonten, T.N., Mook-Kanamori, D.O., Noordam, R., Li-Gao, R.F., Jarvelin, M.R., Wielscher, M., Terzikhan, N., Lahousse, L., Brusselle, G., Weiss, S., Ewert, R., Glaser, S., Homuth, G., Shrine, N., Hall, I.P., Tobin, M., London, S.J., Wei, P., Morrison, A.C.
Published 2021

Genome-wide association analysis identifies six new loci associated with forced vital capacity

by Loth, D.W., Artigas, M.S., Gharib, S.A., Wain, L.V., Franceschini, N., Koch, B., Pottinger, T.D., Smith, A.V., Duan, Q., Oldmeadow, C., Lee, M.K., Strachan, D.P., James, A.L., Huffman, J.E., Vitart, V., Ramasamy, A., Wareham, N.J., Kaprio, J., Wang, X.Q., Trochet, H., Kahonen, M., Flexeder, C., Albrecht, E., Lopez, L.M., Jong, K. de, Thyagarajan, B., Alves, A.C., Enroth, S., Omenaas, E., Joshi, P.K., Fall, T., Vinuela, A., Launer, L.J., Loehr, L.R., Fornage, M., Li, G., Wik, J.B., Tang, W.B., Manichaikul, A., Lahousse, L., Harris, T.B., North, K.E., Rudnicka, A.R., Hui, J., Gu, X.J., Lumley, T., Wright, A.F., Hastie, N.D., Campbell, S., Kumar, R., Pin, I., Scott, R.A., Pietilainen, K.H., Surakka, I., Liu, Y.M., Holliday, E.G., Schulz, H., Heinrich, J., Davies, G., Vonk, J.M., Wojczynski, M., Pouta, A., Johansson, A., Wild, S.H., Ingelsson, E., Rivadeneira, F., Vozke, H., Hysi, P.G., Eiriksdottir, G., Morrison, A.C., Rotter, J.I., Gao, W., Postma, D.S., White, W.B., Rich, S.S., Hofman, A., Aspelund, T., Couper, D., Smith, L.J., Psaty, B.M., Lohman, K., Burchard, E.G., Uitterlinden, A.G., Garcia, M., Joubert, B.R., McArdle, W.L., Musk, A.B., Hansel, N., Heckbert, S.R., Zgaga, L., Meurs, J.B.J. van, Navarro, P., Rudan, I., Oh, Y.M., Redline, S., Jarvis, D.L., Zhao, J.H., Rantanen, T., O'Connor, G.T., Ripatti, S., Scott, R.J., Karrasch, S., Grallert, H., Gaddis, N.C., Starr, J.M., Wijmenga, C., Minster, R.L., Lederer, D.J., Pekkanen, J., Gyllensten, U., Campbe, H., Morris, A.P., Glaser, S., Hammond, C.J., Burkart, K.M., Beilby, J., Kritchevsky, S.B., Gucinason, V., Hancock, D.B., Williams, D., Polasek, O., Zemunik, T., Kolcic, I., Petrini, M.F., Wjst, M., Kim, W.J., Porteous, D.J., Scotland, G., Smith, B.H., Villanen, A., Heliovaara, M., Attia, J.R., Sayers, I., Hampel, R., Gieger, C., Deary, I.J., Boezen, H.M., Newman, A., Jarvelin, M.R., Wilson, J.F., Lind, L., Stricker, B.H., Teumer, A., Spector, T.D., Melen, E., Peters, M.J., Lange, L.A., Barr, R.G., Bracke, K.R., Verhamme, F.M., Sung, J., Hiemstra, P.S., Cassano, P.A., Sood, A., Hayward, C., Dupuis, J., Hall, I.P., Brusselle, G.G., Tobin, M.D., London, S.J.
Published 2014

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

by Wain, LV, Shrine, N, Artigas, MS, Erzurumluoglu, AM, Noyvert, B, Bossini-Castillo, L, Obeidat, M, Henry, AP, Portelli, MA, Hall, RJ, Billington, CK, Rimington, TL, Fenech, AG, John, C, Blake, T, Jackson, VE, Allen, RJ, Prins, BP, Understanding Society Scientific Group, Campbell, A, Porteous, DJ, Jarvelin, M-R, Wielscher, M, James, AL, Hui, J, Wareham, NJ, Zhao, JH, Wilson, JF, Joshi, PK, Stubbe, B, Rawal, R, Schulz, H, Imboden, M, Probst-Hensch, NM, Karrasch, S, Gieger, C, Deary, IJ, Harris, SE, Marten, J, Rudan, I, Enroth, S, Gyllensten, U, Kerr, SM, Polasek, O, Kähönen, M, Surakka, I, Vitart, V, Hayward, C, Lehtimäki, T, Raitakari, OT, Evans, DM, Henderson, AJ, Pennell, CE, Wang, CA, Sly, PD, Wan, ES, Busch, R, Hobbs, BD, Litonjua, AA, Sparrow, DW, Gulsvik, A, Bakke, PS, Crapo, JD, Beaty, TH, Hansel, NN, Mathias, RA, Ruczinski, I, Barnes, KC, Bossé, Y, Joubert, P, van den Berge, M, Brandsma, C-A, Paré, PD, Sin, DD, Nickle, DC, Hao, K, Gottesman, O, Dewey, FE, Bruse, SE, Carey, DJ, Kirchner, HL, Geisinger-Regeneron DiscovEHR Collaboration, Jonsson, S, Thorleifsson, G, Jonsdottir, I, Gislason, T, Stefansson, K, Schurmann, C, Nadkarni, G, Bottinger, EP, Loos, RJF, Walters, RG, Chen, Z, Millwood, IY, Vaucher, J, Kurmi, OP, Li, L, Hansell, AL, Brightling, C, Zeggini, E, Cho, MH, Silverman, EK, Sayers, I, Trynka, G, Morris, AP, Strachan, DP, Hall, IP, Tobin, MD
Published 2017

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

by Sakornsakolpat, P., Prokopenko, D., Lamontagne, M., Reeve, N.F., Guyatt, A.L., Jackson, V.E., Shrine, N., Qiao, D.D., Bartz, T.M., Kim, D.K., Lee, M.K., Latourelle, J.C., Li, X.N., Morrow, J.D., Obeidat, M., Wyss, A.B., Bakke, P., Barr, R.G., Beaty, T.H., Belinsky, S.A., Brusselle, G.G., Crapo, J.D., Jong, K. de, DeMeo, D.L., Fingerlin, T.E., Gharib, S.A., Gulsvik, A., Hall, I.P., Hokanson, J.E., Kim, W.J., Lomas, D.A., London, S.J., Meyers, D.A., O'Connor, G.T., Rennard, S.I., Schwartz, D.A., Sliwinski, P., Sparrow, D., Strachan, D.P., Tal-Singer, R., Tesfaigzi, Y., Vestbo, J., Vonk, J.M., Yim, J.J., Zhou, X.B., Bosse, Y., Manichaikul, A., Lahousse, L., Silverman, E.K., Boezen, H.M., Wain, L.V., Tobin, M.D., Hobbs, B.D., Cho, M.H., Batini, C., Zhao, J.H., Wielscher, M., Weiss, S., Kentistou, K.A., Cook, J.P., Hui, J.N., Karrasch, S., Imboden, M., Harris, S.E., Marten, J., Enroth, S., Kerr, S.M., Surakka, I., Vitart, V., Lehtimaki, T., Ewert, R., Gieger, C., Homuth, G., Joshi, P.K., Langenberg, C., Lind, L., Luan, J.N., Mahajan, A., Murray, A., Porteous, D.J., Rawal, R., Smith, B.H., Timmers, P.R.H.J., Raitakari, O.T., Kahonen, M., Polasek, O., Gyllensten, U., Rudan, I., Deary, I.J., Probst-Hensch, N.M., Schulz, H., James, A.L., Wilson, J.F., Stubbe, B., Zeggini, E., Jarvelin, M.R., Wareham, N., Hayward, C., Morris, A.P., Agusti, A., Anderson, W., Bakerly, N., Bals, R., Barnes, K.C., Bleecker, E.R., Bowler, R., Brightling, C., Bruijne, M. de, Castaldi, P., Celli, B., Coxson, H.O., Crystal, R., Jong, P. de, Dirksen, A., Dy, J., Foreman, M., Garcia-Aymerich, J., Gevenois, P., Ghosh, S., Gietema, H., Hansel, N., Hersh, C.P., Hoffman, E., Kalsheker, N., Kauczor, H.U., Laitinen, T., Lambrechts, D., Litonjua, A.A., Loth, D.W., Lutz, S.M., Lynch, D., MacNee, W., McDonald, M.L., Newell, J.D., Nordestgaard, B.G., Oh, Y.M., Pare, P.D., Pistolesi, M., Postma, D.S., Puhan, M., Regan, E., Rich, S.S., Seo, J.B., Short, A., Stoel, B., Sverzellati, N., Riet, G. ter, Beek, E.J.R. van, Ginneken, B. van, Vogelmeier, C.F., Wanner, A., Washko, G., Wauters, E., Wouters, E.F.M., Young, R.P., Zeigler-Heitbrock, L., SpiroMeta Consortium, Int COPD Genetics Consortium, Understanding Soc Sci Grp
Published 2019

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

by Erzurumluoglu, A.M., Liu, M.Z., Jackson, V.E., Barnes, D.R., Datta, G., Melbourne, C.A., Young, R., Batini, C., Surendran, P., Jiang, T., Adnan, S.D., Afaq, S., Agrawal, A., Altmaier, E., Antoniou, A.C., Asselbergs, F.W., Baumbach, C., Bierut, L., Bertelsen, S., Boehnke, M., Bots, M.L., Brazel, D.M., Chambers, J.C., Chang-Claude, J., Chen, C., Corley, J., Chou, Y.L., David, S.P., Boer, R.A. de, Leeuw, C.A. de, Dennis, J.G., Dominiczak, A.F., Dunning, A.M., Easton, D.F., Eaton, C., Elliott, P., Evangelou, E., Faul, J.D., Foroud, T., Goate, A., Gong, J., Grabe, H.J., Haessler, J., Haiman, C., Hallmans, G., Hammerschlag, A.R., Harris, S.E., Hattersley, A., Heath, A., Hsu, C., Iacono, W.G., Kanoni, S., Kapoor, M., Kaprio, J., Kardia, S.L., Karpe, F., Kontto, J., Kooner, J.S., Kooperberg, C., Kuulasmaa, K., Laakso, M., Lai, D.B., Langenberg, C., , N. le, Lettre, G., Loukola, A., Luan, J.N., Madden, P.A.F., Mangino, M., Marioni, R.E., Marouli, E., Marten, J., Martin, N.G., McGue, M., Michailidou, K., Mihailov, E., Moayyeri, A., Moitry, M., Muller-Nurasyid, M., Naheed, A., Nauck, M., Neville, M.J., Nielsen, S.F., North, K., Perola, M., Pharoah, P.D.P., Pistis, G., Polderman, T.J., Posthuma, D., Poulter, N., Qaiser, B., Rasheed, A., Reiner, A., Renstrom, F., Rice, J., Rohde, R., Rolandsson, O., Samani, N.J., Samuel, M., Schlessinger, D., Scholte, S.H., Scott, R.A., Sever, P., Shao, Y.M., Shrine, N., Smith, J.A., Starr, J.M., Stirrups, K., Stram, D., Stringham, H.M., Tachmazidou, I., Tardif, J.C., Thompson, D.J., Tindle, H.A., Tragante, V., Trompet, S., Turcot, V., Tyrrell, J., Vaartjes, I., Leij, A.R. van der, Meer, P. van der, Varga, T.V., Verweij, N., Voelzke, H., Wareham, N.J., Warren, H.R., Weir, D.R., Weiss, S., Wetherill, L., Yaghootkar, H., Yavas, E., Jiang, Y., Chen, F., Zhan, X.W., Zhang, W.H., Zhao, W., Zhou, K.X., Amouyel, P., Blankenberg, S., Caulfield, M.J., Chowdhury, R., Cucca, F., Deary, I.J., Deloukas, P., Angelantonio, E. di, Ferrario, M., Ferrieres, J., Franks, P.W., Frayling, T.M., Frossard, P., Hall, I.P., Hayward, C., Jansson, J.H., Jukema, J.W., Kee, F., Mannisto, S., Metspalu, A., Munroe, P.B., Nordestgaard, B.G., Palmer, C.N.A., Salomaa, V., Sattar, N., Spector, T., Strachan, D.P., Harst, P. van der, Zeggini, E., Saleheen, D., Butterworth, A.S., Wain, L.V., Abecasis, G.R., Danesh, J., Tobin, M.D., Vrieze, S., Liu, D.J.J., Howson, J.M.M.
Published 2020