Editorial: Translation of genetically engineered T cells in cancer immunotherapy

by Ralf-Holger Voss, Hakim Echchannaoui, Hakim Echchannaoui, Hakim Echchannaoui, He Huang, Shao-An Xue, Shao-An Xue
Published 2023-09-01

Inhibition of Arginase 1 Liberates Potent T Cell Immunostimulatory Activity of Human Neutrophil Granulocytes

by Verena Vonwirth, Yagmur Bülbül, Anke Werner, Hakim Echchannaoui, Hakim Echchannaoui, Johannes Windschmitt, Alice Habermeier, Sonia Ioannidis, Niu Shin, Roland Conradi, Matthias Bros, Stefan Tenzer, Matthias Theobald, Matthias Theobald, Matthias Theobald, Ellen Ildicho Closs, Markus Munder, Markus Munder
Published 2021-02-01

P1367: REFINED PHENOTYPE OF SENESCENT T CELLS UNVEILS HIGH ANTI-TUMOR ACTIVITY DESPITE IMPAIRED PROLIFERATION AND DISTURBED METABOLIC ACTIVITY: NEW IMPLICATIONS FOR CANCER IMMUNOTH...

by Kevin Legscha, Abdulkadir Yilmaz, Lea Märker, Edite Antunes, Catherine Wölfel, Borhane Guezguez, Stefan Porubsky, Matthias Theobald, Hakim Echchannaoui
Published 2023-08-01

Cationic Amino Acid Transporter-1-Mediated Arginine Uptake Is Essential for Chronic Lymphocytic Leukemia Cell Proliferation and Viability

by Anke Werner, Anke Werner, Daniel Pieh, Hakim Echchannaoui, Johanna Rupp, Krishnaraj Rajalingam, Matthias Theobald, Matthias Theobald, Matthias Theobald, Matthias Theobald, Ellen I. Closs, Markus Munder, Markus Munder
Published 2019-11-01

Δ133p53α enhances metabolic and cellular fitness of TCR-engineered T cells and promotes superior antitumor immunity

by Jean-Christophe Bourdon, Kevin Jan Legscha, Edite Antunes Ferreira, Antonios Chamoun, Alexander Lang, Mohamed Hemaid Sayed Awwad, Gigi Nu Hoang Quy Ton, Danuta Galetzka, Borhane Guezguez, Michael Hundemer, Markus Munder, Matthias Theobald, Hakim Echchannaoui
Published 2021-06-01

Menin inhibitor ziftomenib (KO-539) synergizes with drugs targeting chromatin regulation or apoptosis and sensitizes acute myeloid leukemia with <i>MLL</i> rearrangement or <i>NPM1...

by Johanna Rausch, Margarita M. Dzama, Nadezda Dolgikh, Hanna L. Stiller, Stephan R. Bohl, Catharina Lahrmann, Kerstin Kunz, Linda Kessler, Hakim Echchannaoui, Chun-Wei Chen, Thomas Kindler, Konstanze Döhner, Francis Burrows, Matthias Theobald, Daniel Sasca, Michael W.M. Kühn
Published 2023-04-01