Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

by Gudmundsdottir, V., Pedersen, H.K., Allebrandt, K.V., Brorsson, C., Leeuwen, N. van, Banasik, K., Mahajan, A., Groves, C.J., Bunt, M. van de, Dawed, A.Y., Fritsche, A., Steiger, H., Simonis-Bik, A.M.C., Deelen, J., Kramer, M.H.H., Dietrich, A., Hubschle, T., Willemsen, G., Haring, H.U., Geus, E.J.C. de, Boomsma, D.I., Eekhoff, E.M.W., Ferrer, J., McCarthy, M.I., Pearson, E.R., Gupta, R., Brunak, S., Hart, L.M. 't
Published 2018

Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study

by Gudmundsdottir, V., Pedersen, H.K., Mazzoni, G., Allin, K.H., Artati, A., Beulens, J.W., Banasik, K., Brorsson, C., Cederberg, H., Chabanova, E., De Masi, F., Elders, P.J., Forgie, I., Giordano, G.N., Grallert, H., Gupta, R., Haid, M., Hansen, T., Hansen, T.H., Hattersley, A.T., Heggie, A., Hong, M.-G., Jones, A.G., Koivula, R., Kokkola, T., Laakso, M., Løngreen, P., Mahajan, A., Mari, A., McDonald, T.J., McEvoy, D., Musholt, P.B., Pavo, I., Prehn, C., Ruetten, H., Ridderstråle, M., Rutters, F., Sharma, S., Slieker, R.C., Syed, A., Tajes, J.F., Thomas, C.E., Thomsen, H.S., Vangipurapu, J., Vestergaard, H., Viñuela, A., Wesolowska-Andersen, A., Walker, M., Adamski, J., Schwenk, J.M., McCarthy, M.I., Pearson, E., Dermitzakis, E., Franks, P.W., Pedersen, O., Brunak, S.
Published 2021

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

by Molnos, S., Wahl, S., Haid, M., Eekhoff, E.M.W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H.H., Leeuwen, N. van, Simonis-Bik, A.M.C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B., Herder, C., Rathmann, W., Roden, M., Gieger, C., Kramer, M.H.H., Heemst, D. van, Pedersen, H.K., Gudmundsdottir, V., Schulze, M.B., Pischon, T., Geus, E.J.C. de, Boeing, H., Boomsma, D.I., Ziegler, A.G., Slagboom, P.E., Hummel, S., Beekman, M., Grallert, H., Brunak, S., McCarthy, M.I., Gupta, R., Pearson, E.R., Adamski, J., Hart, L.M. 't
Published 2018

Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

by Wesolowska-Andersen, A, Brorsson, CA, Bizzotto, R, Mari, A, Tura, A, Koivula, R, Mahajan, A, Vinuela, A, Tajes, JF, Sharma, S, Haid, M, Prehn, C, Artati, A, Hong, MG, Musholt, PB, Kurbasic, A, De Masi, F, Tsirigos, K, Pedersen, HK, Gudmundsdottir, V, Thomas, CE, Banasik, K, Jennison, C, Jones, A, Kennedy, G, Bell, J, Thomas, L, Frost, G, Thomsen, H, Allin, K, Hansen, TH, Vestergaard, H, Hansen, T, Rutters, F, Elders, P, t'Hart, L, Bonnefond, A, Canouil, M, Brage, Soren, Kokkola, T, Heggie, A, McEvoy, D, Hattersley, A, McDonald, T, Teare, H, Ridderstrale, M, Walker, M, Forgie, I, Giordano, GN, Froguel, P, Pavo, I, Ruetten, H, Pedersen, O, Dermitzakis, E, Franks, PW, Schwenk, JM, Adamski, J, Pearson, E, McCarthy, MI, Brunak, S
Published 2022

Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

by Wesolowska-Andersen, A, Brorsson, CA, Bizzotto, R, Mari, A, Tura, A, Koivula, R, Mahajan, A, Vinuela, A, Tajes, JF, Sharma, S, Haid, M, Prehn, C, Artati, A, Hong, MG, Musholt, PB, Kurbasic, A, De Masi, F, Tsirigos, K, Pedersen, HK, Gudmundsdottir, V, Thomas, CE, Banasik, K, Jennison, C, Jones, A, Kennedy, G, Bell, J, Thomas, L, Frost, G, Thomsen, H, Allin, K, Hansen, TH, Vestergaard, H, Hansen, T, Rutters, F, Elders, P, t'Hart, L, Bonnefond, A, Canouil, M, Brage, S, Kokkola, T, Heggie, A, McEvoy, D, Hattersley, A, McDonald, T, Teare, H, Ridderstrale, M, Walker, M, Forgie, I, Giordano, GN, Froguel, P, Pavo, I, Ruetten, H, Pedersen, O, Dermitzakis, E, Franks, PW, Schwenk, JM, Adamski, J, Pearson, E, McCarthy, MI, Brunak, S
Published 2022

Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts

by DiCorpo, D., LeClair, J., Cole, J.B., Sarnowski, C., Ahmadizar, F., Bielak, L.F., Blokstra, A., Bottinger, E.P., Chaker, L., Chen, Y.D.I., Chen, Y., Vries, P.S. de, Faquih, T., Ghanbari, M., Gudmundsdottir, V., Guo, X.Q., Hasbani, N.R., Ibi, D., Ikram, M.A., Kavousi, M., Leonard, H.L., Leong, A., Mercader, J.M., Morrison, A.C., Nadkarni, G.N., Nalls, M.A., Noordam, R., Preuss, M., Smith, J.A., Trompet, S., Vissink, P., Yao, J., Zhao, W., Boerwinkle, E., Goodarzi, M.O., Gudnason, V., Jukema, J.W., Kardia, S.L.R., Loos, R.J.F., Liu, C.T., Manning, A.K., Mook-Kanamori, D., Pankow, J.S., Picavet, H.S.J., Sattar, N., Simonsick, E.M., Verschuren, W.M.M., Dijk, K.W. van, Florez, J.C., Rotter, J.I., Meigs, J.B., Dupuis, J., Udler, M.S.
Published 2022

Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study

by Gudmundsdottir, V., Pedersen, H.K., Mazzoni, G., Allin, K.H., Artati, A., Beulens, J.W., Banasik, K., Brorsson, C., Cederberg, H., Chabanova, E., Masi, F. de, Elders, P.J., Forgie, I., Giordano, G.N., Grallert, H., Gupta, R., Haid, M., Hansen, T., Hansen, T.H., Hattersley, A.T., Heggie, A., Hong, M.G., Jones, A.G., Koivula, R., Kokkola, T., Laakso, M., Longreen, P., Mahajan, A., Mari, A., McDonald, T.J., McEvoy, D., Musholt, P.B., Pavo, I., Prehn, C., Ruetten, H., Ridderstrale, M., Rutters, F., Sharma, S., Slieker, R.C., Syed, A., Tajes, J.F., Thomas, C.E., Thomsen, H.S., Vangipurapu, J., Vestergaard, H., Vinuela, A., Wesolowska-Andersen, A., Walker, M., Adamski, J., Schwenk, J.M., McCarthy, M.I., Pearson, E., Dermitzakis, E., Franks, P.W., Pedersen, O., Brunak, S.
Published 2020