Friction-Induced Mitochondrial Dysregulation Contributes to Joint Deterioration in Prg4 Knockout Mice

by Kimberly A. Waller, Ling X. Zhang, Gregory D. Jay
Published 2017-06-01

The autocrine role of proteoglycan-4 (PRG4) in modulating osteoarthritic synoviocyte proliferation and expression of matrix degrading enzymes

by Ali Alquraini, Maha Jamal, Ling Zhang, Tannin Schmidt, Gregory D. Jay, Khaled A. Elsaid
Published 2017-05-01

Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration

by Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid
Published 2021-09-01

Proteoglycan-4 regulates fibroblast to myofibroblast transition and expression of fibrotic genes in the synovium

by Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Holly Richendrfer, Tannin A. Schmidt, Khaled A. Elsaid
Published 2020-05-01

Correction to: Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration

by Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid
Published 2021-10-01

Recombinant Human Proteoglycan 4 Regulates Phagocytic Activation of Monocytes and Reduces IL-1β Secretion by Urate Crystal Stimulated Gout PBMCs

by Sandy ElSayed, Gregory D. Jay, Ralph Cabezas, Marwa Qadri, Tannin A. Schmidt, Khaled A. Elsaid
Published 2021-12-01

The effect of lubricin on the gliding resistance of mouse intrasynovial tendon.

by Masanori Hayashi, Chunfeng Zhao, Andrew R Thoreson, Takako Chikenji, Gregory D Jay, Kai-Nan An, Peter C Amadio
Published 2013-01-01

The Effect of Intense Exercise on Equine Serum Proteoglycan-4/Lubricin

by Austyn Matheson, Suresh C. Regmi, Gregory D. Jay, Tannin A. Schmidt, W. Michael Scott, W. Michael Scott
Published 2020-12-01

Prediction of anemia in real-time using a smartphone camera processing conjunctival images

by Leon Zhao, Alisa Vidwans, Courtney J. Bearnot, James Rayner, Timmy Lin, Janette Baird, Selim Suner, Gregory D. Jay
Published 2024-01-01

Prediction of anemia and estimation of hemoglobin concentration using a smartphone camera.

by Selim Suner, James Rayner, Ibrahim U Ozturan, Geoffrey Hogan, Caroline P Meehan, Alison B Chambers, Janette Baird, Gregory D Jay
Published 2021-01-01

Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFα-Stimulated NFκB Activity and FAT10 Expression in Human Corneal Epithelial Cells

by Nikhil G. Menon, Yasir Suhail, Ruchi Goyal, Wenqiang Du, Adam P. Tanguay, Gregory D. Jay, Mallika Ghosh, Kshitiz, Tannin A. Schmidt
Published 2022-10-01

Recombinant human proteoglycan-4 reduces phagocytosis of urate crystals and downstream nuclear factor kappa B and inflammasome activation and production of cytokines and chemokines...

by Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Wendy Wong, Anthony M. Reginato, Changqi Sun, Tannin A. Schmidt, Khaled A. Elsaid
Published 2018-08-01

Recombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFβ-Hyaluronan-CD44 signalling pathway.

by Anusi Sarkar, Ayan Chanda, Suresh C Regmi, Kunal Karve, Lili Deng, Gregory D Jay, Frank R Jirik, Tannin A Schmidt, Shirin Bonni
Published 2019-01-01

Anti-lubricin monoclonal antibodies created using lubricin-knockout mice immunodetect lubricin in several species and in patients with healthy and diseased joints.

by Minrong Ai, Yajun Cui, Man-Sun Sy, David M Lee, Ling Xiu Zhang, Katherine M Larson, Kyle C Kurek, Gregory D Jay, Matthew L Warman
Published 2015-01-01

Quadruped Gait and Regulation of Apoptotic Factors in Tibiofemoral Joints following Intra-Articular rhPRG4 Injection in <i>Prg4</i> Null Mice

by Daniel S. Yang, Edward E. Dickerson, Ling X. Zhang, Holly Richendrfer, Padmini N. Karamchedu, Gary J. Badger, Tannin A. Schmidt, Alger M. Fredericks, Khaled A. Elsaid, Gregory D. Jay
Published 2022-04-01

Noncovalent hyaluronan crosslinking by TSG-6: Modulation by heparin, heparan sulfate, and PRG4

by Yun Jin Ashley Sin, Rebecca MacLeod, Adam P. Tanguay, Andrew Wang, Olivia Braender-Carr, Teraesa M. Vitelli, Gregory D. Jay, Tannin A. Schmidt, Mary K. Cowman, Mary K. Cowman
Published 2022-10-01

Tryptase β regulation of joint lubrication and inflammation via proteoglycan-4 in osteoarthritis

by Nabangshu Das, Luiz G. N. de Almeida, Afshin Derakhshani, Daniel Young, Kobra Mehdinejadiani, Paul Salo, Alexander Rezansoff, Gregory D. Jay, Christian P. Sommerhoff, Tannin A. Schmidt, Roman Krawetz, Antoine Dufour
Published 2023-04-01

Author Correction: Cathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin

by Shan Huang, Kristina A. Thomsson, Chunsheng Jin, Sally Alweddi, André Struglics, Ola Rolfson, Lena I. Björkman, Sebastian Kalamajski, Tannin A. Schmidt, Gregory D. Jay, Roman Krawetz, Niclas G. Karlsson, Thomas Eisler
Published 2021-02-01

Truncated lubricin glycans in osteoarthritis stimulate the synoviocyte secretion of VEGFA, IL-8, and MIP-1α: Interplay between O-linked glycosylation and inflammatory cytokines

by Shan Huang, Kristina A. Thomsson, Chunsheng Jin, Henrik Ryberg, Nabangshu Das, Nabangshu Das, André Struglics, Ola Rolfson, Lena I. Björkman, Thomas Eisler, Tannin A. Schmidt, Gregory D. Jay, Roman Krawetz, Roman Krawetz, Niclas G. Karlsson, Niclas G. Karlsson
Published 2022-09-01

Proteomics Analysis of Tears and Saliva From Sjogren’s Syndrome Patients

by Nabangshu Das, Nabangshu Das, Nikhil G. Menon, Luiz G. N. de Almeida, Luiz G. N. de Almeida, Paige S. Woods, Miriam L. Heynen, Gregory D. Jay, Barbara Caffery, Lyndon Jones, Roman Krawetz, Roman Krawetz, Tannin A. Schmidt, Tannin A. Schmidt, Antoine Dufour, Antoine Dufour, Antoine Dufour
Published 2021-12-01