Single-cell and Spatially Resolved Transcriptome Analysis Reveals Cellular Heterogeneities and Novel Regulators of Atherosclerotic Plaque Destabilization

by Jessica Pauli, Zhiyuan Wu, Chika Yokota, Greg Winski, Valentina Paloschi, Anne Dueck, Stefan Engelhardt, Hans-Henning Eckstein, Muredach P. Reilly, Lars Maegdefessel
Published 2022-01-01

MicroRNA-15A is a Potential Circulating Biomarker of Abdominal Aortic Aneurysm with Both Diagnostic and Prognostic Properties

by Greg Winski, Suzanne M. Eken, Ekaterina Chernogubova, Albert Busch, Hong Jin, Hanna Winter, Joshua M. Spin, Alexandra Bäcklund, Philip S. Tsao, Lars Maegdefessel
Published 2020-01-01

Apolipoprotein E (ApoE) Rescues the Contractile Smooth Muscle Cell Phenotype in Popliteal Artery Aneurysm Disease

by Jessica Pauli, Tessa Reisenauer, Greg Winski, Nadja Sachs, Ekaterina Chernogubova, Hannah Freytag, Christoph Otto, Christian Reeps, Hans-Henning Eckstein, Claus-Jürgen Scholz, Lars Maegdefessel, Albert Busch
Published 2023-07-01

The circular RNA Ataxia Telangiectasia Mutated regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms

by Francesca Fasolo, Greg Winski, Zhaolong Li, Zhiyan Wu, Hanna Winter, Julia Ritzer, Nadiya Glukha, Joy Roy, Rebecka Hultgren, Jessica Pauli, Albert Busch, Nadja Sachs, Christoph Knappich, Hans-Henning Eckstein, Reinier A. Boon, Valentina Paloschi, Lars Maegdefessel
Published 2023-09-01

Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility

by Albert Busch, Jessica Pauli, Greg Winski, Sonja Bleichert, Ekaterina Chernogubova, Susanne Metschl, Hanna Winter, Matthias Trenner, Armin Wiegering, Christoph Otto, Johannes Fischer, Judith Reiser, Julia Werner, Joy Roy, Christine Brostjan, Christoph Knappich, Hans-Henning Eckstein, Valentina Paloschi, Lars Maegdefessel
Published 2021-08-01

Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification

by Till Seime, Asim Cengiz Akbulut, Moritz Lindquist Liljeqvist, Antti Siika, Hong Jin, Greg Winski, Rick H. van Gorp, Eva Karlöf, Mariette Lengquist, Andrew J. Buckler, Malin Kronqvist, Olivia J. Waring, Jan H. N. Lindeman, Erik A. L. Biessen, Lars Maegdefessel, Anton Razuvaev, Leon J. Schurgers, Ulf Hedin, Ljubica Matic
Published 2021-05-01

miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease

by Suzanne M. Eken, MD, PhD, Tinna Christersdottir, MD, Greg Winski, MD, Traimate Sangsuwan, MSc, Hong Jin, MD, PhD, Ekaterina Chernogubova, PhD, John Pirault, PhD, Changyan Sun, MSc, Nancy Simon, MSc, Hanna Winter, MSc, Alexandra Backlund, PhD, Siamak Haghdoost, PhD, Göran K. Hansson, MD, PhD, Martin Halle, MD, PhD, Lars Maegdefessel, MD, PhD
Published 2019-02-01