Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting

by Zhenfang Du, Benjamin P. Brown, Soyeon Kim, Donna Ferguson, Dean C. Pavlick, Gowtham Jayakumaran, Ryma Benayed, Jean-Nicolas Gallant, Yun-Kai Zhang, Yingjun Yan, Monica Red-Brewer, Siraj M. Ali, Alexa B. Schrock, Ahmet Zehir, Marc Ladanyi, Adam W. Smith, Jens Meiler, Christine M. Lovly
Published 2021-03-01

Mutant-RB1 circulating tumor DNA in the blood of unilateral retinoblastoma patients: What happens during enucleation surgery: A pilot study

by David H. Abramson, Diana L. Mandelker, A. Rose Brannon, Ira J. Dunkel, Ryma Benayed, Michael F. Berger, Maria E. Arcila, Marc Ladanyi, Danielle Novetsky Friedman, Gowtham Jayakumaran, Monica S. Diosdado, Melissa A. Robbins, Dianna Haggag-Lindgren, Neerav Shukla, Michael F. Walsh, Prachi Kothari, Dana W. Y. Tsui, Jasmine H. Francis
Published 2023-01-01

Mutant-RB1 circulating tumor DNA in the blood of unilateral retinoblastoma patients: What happens during enucleation surgery: A pilot study.

by David H Abramson, Diana L Mandelker, A Rose Brannon, Ira J Dunkel, Ryma Benayed, Michael F Berger, Maria E Arcila, Marc Ladanyi, Danielle Novetsky Friedman, Gowtham Jayakumaran, Monica S Diosdado, Melissa A Robbins, Dianna Haggag-Lindgren, Neerav Shukla, Michael F Walsh, Prachi Kothari, Dana W Y Tsui, Jasmine H Francis
Published 2023-01-01

Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients

by Ozge Ceyhan-Birsoy, Gowtham Jayakumaran, Yelena Kemel, Maksym Misyura, Umut Aypar, Sowmya Jairam, Ciyu Yang, Yirong Li, Nikita Mehta, Anna Maio, Angela Arnold, Erin Salo-Mullen, Margaret Sheehan, Aijazuddin Syed, Michael Walsh, Maria Carlo, Mark Robson, Kenneth Offit, Marc Ladanyi, Jorge S. Reis-Filho, Zsofia K. Stadler, Liying Zhang, Alicia Latham, Ahmet Zehir, Diana Mandelker
Published 2022-08-01

Retrospective Evaluation of Somatic Alterations in Cell-Free DNA from Blood in Retinoblastoma

by David H. Abramson, MD, Diana Mandelker, MD, PhD, Jasmine H. Francis, MD, Ira J. Dunkel, MD, A. Rose Brannon, PhD, Ryma Benayed, PhD, Michael F. Berger, PhD, Maria E. Arcila, MD, Marc Ladanyi, MD, Danielle Novetsky Friedman, MD, Gowtham Jayakumaran, MS, Monica S. Diosdado, MA, Melissa A. Robbins, MPH, Dianna Haggag-Lindgren, BS, Neerav Shukla, MD, Michael Walsh, MD, Prachi Kothari, DO, Dana W.Y. Tsui, PhD
Published 2021-03-01

Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing

by Ryan N. Ptashkin, Mark D. Ewalt, Gowtham Jayakumaran, Iwona Kiecka, Anita S. Bowman, JinJuan Yao, Jacklyn Casanova, Yun-Te David Lin, Kseniya Petrova-Drus, Abhinita S. Mohanty, Ruben Bacares, Jamal Benhamida, Satshil Rana, Anna Razumova, Chad Vanderbilt, Anoop Balakrishnan Rema, Ivelise Rijo, Julie Son-Garcia, Ino de Bruijn, Menglei Zhu, Sean Lachhander, Wei Wang, Mohammad S. Haque, Venkatraman E. Seshan, Jiajing Wang, Ying Liu, Khedoudja Nafa, Laetitia Borsu, Yanming Zhang, Umut Aypar, Sarah P. Suehnholz, Debyani Chakravarty, Jae H. Park, Omar Abdel-Wahab, Anthony R. Mato, Wenbin Xiao, Mikhail Roshal, Mariko Yabe, Connie Lee Batlevi, Sergio Giralt, Gilles Salles, Raajit Rampal, Martin Tallman, Eytan M. Stein, Anas Younes, Ross L. Levine, Miguel-Angel Perales, Marcel R. M. van den Brink, Ahmet Dogan, Marc Ladanyi, Michael F. Berger, A. Rose Brannon, Ryma Benayed, Ahmet Zehir, Maria E. Arcila
Published 2023-10-01

Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS

by A. Rose Brannon, Gowtham Jayakumaran, Monica Diosdado, Juber Patel, Anna Razumova, Yu Hu, Fanli Meng, Mohammad Haque, Justyna Sadowska, Brian J. Murphy, Tessara Baldi, Ian Johnson, Ryan Ptashkin, Maysun Hasan, Preethi Srinivasan, Anoop Balakrishnan Rema, Ivelise Rijo, Aaron Agarunov, Helen Won, Dilmi Perera, David N. Brown, Aliaksandra Samoila, Xiaohong Jing, Erika Gedvilaite, Julie L. Yang, Dennis P. Stephens, Jenna-Marie Dix, Nicole DeGroat, Khedoudja Nafa, Aijazuddin Syed, Alan Li, Emily S. Lebow, Anita S. Bowman, Donna C. Ferguson, Ying Liu, Douglas A. Mata, Rohit Sharma, Soo-Ryum Yang, Tejus Bale, Jamal K. Benhamida, Jason C. Chang, Snjezana Dogan, Meera R. Hameed, Jaclyn F. Hechtman, Christine Moung, Dara S. Ross, Efsevia Vakiani, Chad M. Vanderbilt, JinJuan Yao, Pedram Razavi, Lillian M. Smyth, Sarat Chandarlapaty, Gopa Iyer, Wassim Abida, James J. Harding, Benjamin Krantz, Eileen O’Reilly, Helena A. Yu, Bob T. Li, Charles M. Rudin, Luis Diaz, David B. Solit, Maria E. Arcila, Marc Ladanyi, Brian Loomis, Dana Tsui, Michael F. Berger, Ahmet Zehir, Ryma Benayed
Published 2021-06-01