Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer’s Disease

by Mehmet Ilyas Cosacak, Prabesh Bhattarai, Philip L. De Jager, Vilas Menon, Giuseppe Tosto, Caghan Kizil
Published 2022-05-01

Rare Variants Imputation in Admixed Populations: Comparison Across Reference Panels and Bioinformatics Tools

by Sanjeev Sariya, Sanjeev Sariya, Joseph H. Lee, Joseph H. Lee, Joseph H. Lee, Richard Mayeux, Richard Mayeux, Richard Mayeux, Badri N. Vardarajan, Badri N. Vardarajan, Dolly Reyes-Dumeyer, Dolly Reyes-Dumeyer, Jennifer J. Manly, Jennifer J. Manly, Jennifer J. Manly, Adam M. Brickman, Adam M. Brickman, Adam M. Brickman, Rafael Lantigua, Martin Medrano, Ivonne Z. Jimenez-Velazquez, Giuseppe Tosto, Giuseppe Tosto, Giuseppe Tosto
Published 2019-04-01

KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer’s Disease

by Tohid Siddiqui, Prabesh Bhattarai, Stanislava Popova, Mehmet Ilyas Cosacak, Sanjeev Sariya, Yixin Zhang, Richard Mayeux, Giuseppe Tosto, Caghan Kizil
Published 2021-10-01

Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease.

by Christiane Reitz, Giuseppe Tosto, Richard Mayeux, Jose A Luchsinger, NIA-LOAD/NCRAD Family Study Group, Alzheimer's Disease Neuroimaging Initiative
Published 2012-01-01

The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms

by Daniel Felsky, Ismael Santa-Maria, Mehmet Ilyas Cosacak, Leon French, Julie A. Schneider, David A. Bennett, Philip L. De Jager, Caghan Kizil, Giuseppe Tosto
Published 2023-01-01

Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease

by Min Qiao, Annie J. Lee, Dolly Reyes‐Dumeyer, Giuseppe Tosto, Kelley Faber, Alison Goate, Alan Renton, Michael Chao, Brad Boeve, Carlos Cruchaga, Margaret Pericak‐Vance, Jonathan L. Haines, Roger Rosenberg, Debby Tsuang, Robert A. Sweet, David A. Bennett, Robert S. Wilson, Tatiana Foroud, Richard Mayeux, Badri N. Vardarajan
Published 2023-05-01

Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease

by Tohid Siddiqui, Mehmet Ilyas Cosacak, Stanislava Popova, Prabesh Bhattarai, Elanur Yilmaz, Annie J. Lee, Yuhao Min, Xue Wang, Mariet Allen, Özkan İş, Zeynep Tansu Atasavum, Natalia Rodriguez-Muela, Badri N. Vardarajan, Delaney Flaherty, Andrew F. Teich, Ismael Santa-Maria, Uwe Freudenberg, Carsten Werner, Giuseppe Tosto, Richard Mayeux, Nilüfer Ertekin-Taner, Caghan Kizil
Published 2023-07-01

Chromosome 10q24.32 Variants Associate With Brain Arterial Diameters in Diverse Populations: A Genome‐Wide Association Study

by Minghua Liu, Farid Khasiyev, Sanjeev Sariya, Antonio Spagnolo‐Allende, Danurys L Sanchez, Howard Andrews, Qiong Yang, Alexa Beiser, Ye Qiao, Emy A Thomas, Jose Rafael Romero, Tatjana Rundek, Adam M Brickman, Jennifer J Manly, Mitchell SV Elkind, Sudha Seshadri, Christopher Chen, Saima Hilal, Bruce A Wasserman, Giuseppe Tosto, Myriam Fornage, Jose Gutierrez
Published 2023-12-01

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease.

by Seonjoo Lee, Molly E Zimmerman, Atul Narkhede, Sara E Nasrabady, Giuseppe Tosto, Irene B Meier, Tammie L S Benzinger, Daniel S Marcus, Anne M Fagan, Nick C Fox, Nigel J Cairns, David M Holtzman, Virginia Buckles, Bernardino Ghetti, Eric McDade, Ralph N Martins, Andrew J Saykin, Colin L Masters, John M Ringman, Stefan Fӧrster, Peter R Schofield, Reisa A Sperling, Keith A Johnson, Jasmeer P Chhatwal, Stephen Salloway, Stephen Correia, Clifford R Jack, Michael Weiner, Randall J Bateman, John C Morris, Richard Mayeux, Adam M Brickman, Dominantly Inherited Alzheimer Network
Published 2018-01-01