Phenome-wide association study of loci harboring de novo tandem repeat mutations in UK Biobank exomes

by Frank R. Wendt, Gita A. Pathak, Renato Polimanti
Published 2022-12-01

Mitochondrial tRNA methylation in Alzheimer’s disease and progressive supranuclear palsy

by Talisa K. Silzer, Gita A. Pathak, Nicole R. Phillips
Published 2020-05-01

Characterizing the polygenic architecture of complex traits in populations of East Asian and European descent

by Antonella De Lillo, Frank R. Wendt, Gita A. Pathak, Renato Polimanti
Published 2023-07-01

Heterogeneity and Polygenicity in Psychiatric Disorders: A Genome-Wide Perspective

by Frank R. Wendt, Gita A. Pathak, Daniel S. Tylee, Aranyak Goswami, Renato Polimanti
Published 2020-05-01

Polygenic risk for autism spectrum disorder associates with anger recognition in a neurodevelopment-focused phenome-wide scan of unaffected youths from a population-based cohort.

by Frank R Wendt, Carolina Muniz Carvalho, Gita A Pathak, Joel Gelernter, Renato Polimanti
Published 2020-09-01

Deciphering the Biological Mechanisms Underlying the Genome-Wide Associations between Computerized Device Use and Psychiatric Disorders

by Frank R Wendt, Carolina Muniz Carvalho, Gita A. Pathak, Joel Gelernter, Renato Polimanti
Published 2019-11-01

Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European Descent

by Frank R Wendt, Frank R Wendt, Antonella De Lillo, Gita A Pathak, Gita A Pathak, Flavio De Angelis, Flavio De Angelis, COVID-19 Host Genetics Initiative, Renato Polimanti, Renato Polimanti
Published 2021-12-01

ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 Susceptibility

by Gita A. Pathak, Gita A. Pathak, Frank R. Wendt, Frank R. Wendt, Aranyak Goswami, Aranyak Goswami, Dora Koller, Dora Koller, Flavio De Angelis, Flavio De Angelis, COVID-19 Host Genetics Initiative, Renato Polimanti, Renato Polimanti
Published 2021-08-01

Genetically-regulated transcriptomics & copy number variation of proctitis points to altered mitochondrial and DNA repair mechanisms in individuals of European ancestry

by Gita A. Pathak, Renato Polimanti, Talisa K. Silzer, Frank R. Wendt, Ranajit Chakraborty, Nicole R. Phillips
Published 2020-10-01

Drinking and smoking polygenic risk is associated with childhood and early-adulthood psychiatric and behavioral traits independently of substance use and psychiatric genetic risk

by Flavio De Angelis, Frank R. Wendt, Gita A. Pathak, Daniel S. Tylee, Aranyak Goswami, Joel Gelernter, Renato Polimanti
Published 2021-11-01

Denisovan and Neanderthal archaic introgression differentially impacted the genetics of complex traits in modern populations

by Dora Koller, Frank R. Wendt, Gita A. Pathak, Antonella De Lillo, Flavio De Angelis, Brenda Cabrera-Mendoza, Serena Tucci, Renato Polimanti
Published 2022-11-01

Clinical spectrum of Transthyretin amyloidogenic mutations among diverse population origins

by Antonella De Lillo, Gita A. Pathak, Aislinn Low, Flavio De Angelis, Sarah Abou Alaiwi, Edward J. Miller, Maria Fuciarelli, Renato Polimanti
Published 2024-03-01

Multi-environment gene interactions linked to the interplay between polysubstance dependence and suicidality

by Renato Polimanti, Daniel F. Levey, Gita A. Pathak, Frank R. Wendt, Yaira Z. Nunez, Robert J. Ursano, Ronald C. Kessler, Henry R. Kranzler, Murray B. Stein, Joel Gelernter
Published 2021-01-01

Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells

by Mary-Ellen Lynall, Blagoje Soskic, James Hayhurst, Jeremy Schwartzentruber, Daniel F. Levey, Gita A. Pathak, Renato Polimanti, Joel Gelernter, Murray B. Stein, Gosia Trynka, Menna R. Clatworthy, Ed Bullmore
Published 2022-10-01

Polygenic scores for empathy associate with posttraumatic stress severity in response to certain traumatic events

by Frank R. Wendt, Varun Warrier, Gita A. Pathak, Karestan C. Koenen, Murray B. Stein, John H. Krystal, Robert H. Pietrzak, Joel Gelernter, Elizabeth V. Goldfarb, Simon Baron-Cohen, Renato Polimanti
Published 2022-03-01

Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization

by Gita A. Pathak, Kritika Singh, Tyne W. Miller-Fleming, Frank R. Wendt, Nava Ehsan, Kangcheng Hou, Ruth Johnson, Zeyun Lu, Shyamalika Gopalan, Loic Yengo, Pejman Mohammadi, Bogdan Pasaniuc, Renato Polimanti, Lea K. Davis, Nicholas Mancuso
Published 2021-07-01

Disentangling sex differences in the shared genetic architecture of posttraumatic stress disorder, traumatic experiences, and social support with body size and composition

by Carolina Muniz Carvalho, Frank R. Wendt, Gita A. Pathak, Adam X. Maihofer, Dan J. Stein, Jennifer A. Sumner, Sian M.J. Hemmings, Caroline M. Nievergelt, Karestan C. Koenen, Joel Gelernter, Sintia I. Belangero, Renato Polimanti
Published 2021-11-01

Sex differences in the polygenic architecture of hearing problems in adults

by Flavio De Angelis, Oana A. Zeleznik, Frank R. Wendt, Gita A. Pathak, Daniel S. Tylee, Antonella De Lillo, Dora Koller, Brenda Cabrera-Mendoza, Royce E. Clifford, Adam X. Maihofer, Caroline M. Nievergelt, Gary C. Curhan, Sharon G. Curhan, Renato Polimanti
Published 2023-05-01

Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality

by Frank R. Wendt, Gita A. Pathak, Daniel F. Levey, Yaira Z. Nuñez, Cassie Overstreet, Chelsea Tyrrell, Keyrun Adhikari, Flavio De Angelis, Daniel S. Tylee, Aranyak Goswami, John H. Krystal, Chadi G. Abdallah, Murray B. Stein, Henry R. Kranzler, Joel Gelernter, Renato Polimanti
Published 2021-05-01

Modeling the longitudinal changes of ancestry diversity in the Million Veteran Program

by Frank R. Wendt, Gita A. Pathak, Jacqueline Vahey, Xuejun Qin, Dora Koller, Brenda Cabrera-Mendoza, Angela Haeny, Kelly M. Harrington, Nallakkandi Rajeevan, Linh M. Duong, Daniel F. Levey, Flavio De Angelis, Antonella De Lillo, Tim B. Bigdeli, Saiju Pyarajan, VA Million Veteran Program, John Michael Gaziano, Joel Gelernter, Mihaela Aslan, Dawn Provenzale, Drew A. Helmer, Elizabeth R. Hauser, Renato Polimanti, Department of Veteran Affairs Cooperative Study Program (#2006)
Published 2023-06-01