Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns

by Claire H. Masterson, Gerard F. Curley, John G. Laffey
Published 2019-07-01

SARS-CoV-2 uses major endothelial integrin αvβ3 to cause vascular dysregulation in-vitro during COVID-19.

by Danielle Nader, Nicola Fletcher, Gerard F Curley, Steven W Kerrigan
Published 2021-01-01

Cost-effectiveness of a rapid point-of-care test for diagnosing patients with suspected bloodstream infection in Ireland

by Mathilde Vankelegom, David Burke, Amr Mohammed Farghaly Mohammed, Natalie L. McEvoy, Gerard F. Curley, Katy Turner, Amy Pinsent, Elisabeth J. Adams
Published 2022-01-01

Intra-vital imaging of mesenchymal stromal cell kinetics in the pulmonary vasculature during infection

by Claire H. Masterson, Arata Tabuchi, Grace Hogan, Glenn Fitzpatrick, Steven W. Kerrigan, Mirjana Jerkic, Wolfgang M. Kuebler, John G. Laffey, Gerard F. Curley
Published 2021-03-01

Human endothelial cell-derived exosomal microRNA-99a/b drives a sustained inflammatory response during sepsis by inhibiting mTOR expression

by Glenn Fitzpatrick, Glenn Fitzpatrick, Danielle Nader, Danielle Nader, Rebecca Watkin, Rebecca Watkin, Claire E. McCoy, Gerard F. Curley, Steven W. Kerrigan, Steven W. Kerrigan
Published 2022-08-01

Use of a novel “Split” ventilation system in bench and porcine modeling of acute respiratory distress syndrome

by Pierce Geoghegan, Jennifer Clarke, Grace Hogan, Aoife Keogh, Hannah Marsh, Karen Donnelly, Natalie McEvoy, Aoife Doolan, Stephen F. Madden, Ignacio Martin‐Loeches, Michael Power, John G. Laffey, Gerard F. Curley
Published 2022-09-01

Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients.

by Francesco Palmas, Jennifer Clarke, Romain A Colas, Esteban A Gomez, Aoife Keogh, Maria Boylan, Natalie McEvoy, Oliver J McElvaney, Oisin McElvaney, Razi Alalqam, Noel G McElvaney, Gerard F Curley, Jesmond Dalli
Published 2021-01-01

A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19

by Oliver J McElvaney, Brian D Hobbs, Dandi Qiao, Oisín F McElvaney, Matthew Moll, Natalie L McEvoy, Jennifer Clarke, Eoin O'Connor, Seán Walsh, Michael H Cho, Gerard F Curley, Noel G McElvaney
Published 2020-11-01

Corrigendum to ‘A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19’

by Oliver J McElvaney, Brian D Hobbs, Dandi Qiao, Oisín F McElvaney, Matthew Moll, Natalie L McEvoy, Jennifer Clarke, Eoin O'Connor, Sean Walsh, Michael H Cho, Gerard F Curley, Noel G McElvaney
Published 2020-12-01

Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients

by Jennifer Clarke, Pierce Geoghegan, Natalie McEvoy, Maria Boylan, Orna Ní Choileáin, Martin Mulligan, Grace Hogan, Aoife Keogh, Oliver J. McElvaney, Oisín F. McElvaney, John Bourke, Bairbre McNicholas, John G. Laffey, Noel G. McElvaney, Gerard F. Curley
Published 2021-01-01

A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structu...

by Natalie L. McEvoy, Jennifer L. Clarke, Oliver J. Mc Elvaney, Oisin F. Mc Elvaney, Fiona Boland, Deirdre Hyland, Pierce Geoghegan, Karen Donnelly, Oisin Friel, Ailbhe Cullen, Ann M. Collins, Daniel Fraughen, Ignacio Martin-Loeches, Martina Hennessy, John G. Laffey, Noel G. Mc Elvaney, Gerard F. Curley
Published 2021-04-01