Systems Bioinformatics Reveals Possible Relationship between COVID-19 and the Development of Neurological Diseases and Neuropsychiatric Disorders

by Anna Onisiforou, George M. Spyrou
Published 2022-10-01

Immunomodulatory effects of microbiota-derived metabolites at the crossroad of neurodegenerative diseases and viral infection: network-based bioinformatics insights

by Anna Onisiforou, George M. Spyrou
Published 2022-07-01

A guide to multi-omics data collection and integration for translational medicine

by Efi Athieniti, George M. Spyrou
Published 2023-01-01

ProtExA: A tool for post-processing proteomics data providing differential expression metrics, co-expression networks and functional analytics

by George Minadakis, Kleitos Sokratous, George M. Spyrou
Published 2020-01-01

PathIN: an integrated tool for the visualization of pathway interaction networks

by George Minadakis, Kyproula Christodoulou, George Tsouloupas, George M. Spyrou
Published 2023-01-01

Ranking of cell clusters in a single-cell RNA-sequencing analysis framework using prior knowledge.

by Anastasis Oulas, Kyriaki Savva, Nestoras Karathanasis, George M Spyrou
Published 2024-04-01

Drug repurposing on Alzheimer's disease through modulation of NRF2 neighborhood

by Marilena M. Bourdakou, Raquel Fernández-Ginés, Antonio Cuadrado, George M. Spyrou
Published 2023-11-01

A Web Tool for Ranking Candidate Drugs Against a Selected Disease Based on a Combination of Functional and Structural Criteria

by Evangelos Karatzas, George Minadakis, George Kolios, Alex Delis, George M. Spyrou
Published 2019-01-01

Fibrotic expression profile analysis reveals repurposed drugs with potential anti-fibrotic mode of action.

by Evangelos Karatzas, Andrea C Kakouri, George Kolios, Alex Delis, George M Spyrou
Published 2021-01-01

Network-based stage-specific drug repurposing for Alzheimer’s disease

by Kyriaki Savva, Margarita Zachariou, Marilena M. Bourdakou, Nikolas Dietis, George M. Spyrou
Published 2022-01-01

D^Re^Amocracy: A Method to Capitalise on Prior Drug Discovery Efforts to Highlight Candidate Drugs for Repurposing

by Kyriaki Savva, Margarita Zachariou, Marilena M. Bourdakou, Nikolas Dietis, George M. Spyrou
Published 2024-05-01

Putative Antimicrobial Peptides Within Bacterial Proteomes Affect Bacterial Predominance: A Network Analysis Perspective

by Anastasis Oulas, Anastasis Oulas, Margarita Zachariou, Margarita Zachariou, Christos T. Chasapis, Marios Tomazou, Marios Tomazou, Umer Z. Ijaz, Georges Pierre Schmartz, George M. Spyrou, George M. Spyrou, Alexios Vlamis-Gardikas
Published 2021-11-01

PathExNET: A tool for extracting pathway expression networks from gene expression statistics

by George Minadakis, Alfonso Muñoz-Pomer Fuentes, George Tsouloupas, Irene Papatheodorou, George M. Spyrou
Published 2021-01-01

In Silico Identification of Antimicrobial Peptides in the Proteomes of Goat and Sheep Milk and Feta Cheese

by Marios Tomazou, Anastasis Oulas, Athanasios K. Anagnostopoulos, George Th. Tsangaris, George M. Spyrou
Published 2019-09-01

Differential genetic and functional background in inflammatory bowel disease phenotypes of a Greek population: a systems bioinformatics approach

by Maria Gazouli, Nikolas Dovrolis, Andre Franke, George M. Spyrou, Leonardo A. Sechi, George Kolios
Published 2019-06-01

Age-Related Exosomal and Endogenous Expression Patterns of miR-1, miR-133a, miR-133b, and miR-206 in Skeletal Muscles

by Chrystalla Mytidou, Chrystalla Mytidou, Andrie Koutsoulidou, Andrie Koutsoulidou, Margarita Zachariou, Margarita Zachariou, Marianna Prokopi, Marianna Prokopi, Konstantinos Kapnisis, George M. Spyrou, George M. Spyrou, Andreas Anayiotos, Leonidas A. Phylactou, Leonidas A. Phylactou
Published 2021-11-01

Novel clinical, molecular and bioinformatics insights into the genetic background of autism

by Ioanna Talli, Nikolas Dovrolis, Anastasis Oulas, Stavroula Stavrakaki, Kali Makedou, George M. Spyrou, Ioanna Maroulakou
Published 2022-09-01

The Potential Relevance of the Microbiome to Hair Physiology and Regeneration: The Emerging Role of Metagenomics

by Andria Constantinou, Varvara Kanti, Katarzyna Polak-Witka, Ulrike Blume-Peytavi, George M. Spyrou, Annika Vogt
Published 2021-02-01

Analyzing Gene Expression Profiles from Ataxia and Spasticity Phenotypes to Reveal Spastic Ataxia Related Pathways

by Andrea C. Kakouri, Christina Votsi, Marios Tomazou, George Minadakis, Evangelos Karatzas, Kyproula Christodoulou, George M. Spyrou
Published 2020-09-01

Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes

by Elena D. Christofidou, Marios Tomazou, Chrysovalantis Voutouri, Christina Michael, Triantafyllos Stylianopoulos, George M. Spyrou, Katerina Strati
Published 2024-03-01