Diets with Higher ω-6/ω-3 Ratios Show Differences in Ceramides and Fatty Acid Levels Accompanied by Increased Amyloid-Beta in the Brains of Male APP/PS1 Transgenic Mice

by Lara Ordóñez-Gutiérrez, Gemma Fábrias, Josefina Casas, Francisco Wandosell
Published 2021-10-01

A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber disease

by Carmen Bedia, Luz Camacho, José Luís Abad, Gemma Fabriàs, Thierry Levade
Published 2010-12-01

Inhibition of dihydroceramide desaturase activity by the sphingosine kinase inhibitor SKI II[S]

by Francesca Cingolani, Mireia Casasampere, Pol Sanllehí, Josefina Casas, Jordi Bujons, Gemma Fabrias
Published 2014-08-01

High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase

by Mazen Aseeri, José Luis Abad, Antonio Delgado, Gemma Fabriàs, Gemma Triola, Josefina Casas
Published 2023-12-01

Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase

by Francesca Cingolani, Fabio Simbari, Jose Luis Abad, Mireia Casasampere, Gemma Fabrias, Anthony H. Futerman, Josefina Casas
Published 2017-08-01

Corrigendum to “Sphingolipids as Mediators in the Crosstalk between Microbiota and Intestinal Cells: Implications for Inflammatory Bowel Disease”

by Bryan Phillips-Farfán, Karla Carvajal, Edgar Alejandro Medina-Torres, Sara Elva Espinosa-Padilla, Gemma Fabrias, Luz Camacho
Published 2016-01-01

Methuosis Contributes to Jaspine-B-Induced Cell Death

by Núria Bielsa, Mireia Casasampere, Jose Luis Abad, Carlos Enrich, Antonio Delgado, Gemma Fabriàs, Jose M. Lizcano, Josefina Casas
Published 2022-06-01

Sphingosine mediates TNFα-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells

by Chiara Ullio, Josefina Casas, Ulf T. Brunk, Giuseppina Sala, Gemma Fabriàs, Riccardo Ghidoni, Gabriella Bonelli, Francesco M. Baccino, Riccardo Autelli
Published 2012-06-01

Plasmalogen enrichment in exosomes secreted by a nematode parasite versus those derived from its mouse host: implications for exosome stability and biology

by Fabio Simbari, Jana McCaskill, Gillian Coakley, Marissa Millar, Rick M. Maizels, Gemma Fabriás, Josefina Casas, Amy H. Buck
Published 2016-07-01

Glucosylceramide synthesis inhibition affects cell cycle progression, membrane trafficking, and stage differentiation in Giardia lamblia[S]

by Saša Štefanić, Cornelia Spycher, Laura Morf, Gemma Fabriàs, Josefina Casas, Elisabeth Schraner, Peter Wild, Adrian B. Hehl, Sabrina Sonda
Published 2010-09-01

New fluorogenic probes for neutral and alkaline ceramidases

by Mireia Casasampere, Núria Bielsa, Daniel Riba, Laura Bassas, Ruijuan Xu, Cungui Mao, Gemma Fabriàs, José-Luis Abad, Antonio Delgado, Josefina Casas
Published 2019-06-01

S-Adenosyl-l-methionine restores brain mitochondrial membrane fluidity and GSH content improving Niemann-Pick type C disease

by Leire Goicoechea, Sandra Torres, Laura Fàbrega, Mónica Barrios, Susana Núñez, Josefina Casas, Gemma Fabrias, Carmen García-Ruiz, José C. Fernández-Checa
Published 2024-06-01

Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV‐1 Env Clustering

by Jon Ander Nieto‐Garai, Aroa Arboleya, Sara Otaegi, Jakub Chojnacki, Josefina Casas, Gemma Fabriàs, F‐Xabier Contreras, Hans‐Georg Kräusslich, Maier Lorizate
Published 2021-02-01

Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1.

by Nuria Izquierdo-Useros, Maier Lorizate, F-Xabier Contreras, Maria T Rodriguez-Plata, Bärbel Glass, Itziar Erkizia, Julia G Prado, Josefina Casas, Gemma Fabriàs, Hans-Georg Kräusslich, Javier Martinez-Picado
Published 2012-01-01

Activity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols

by Mireia Casasampere, Luz Camacho, Francesca Cingolani, Josefina Casas, Meritxell Egido-Gabás, José Luís Abad, Carmen Bedia, Ruijuan Xu, Kai Wang, Daniel Canals, Yusuf A. Hannun, Cungui Mao, Gemma Fabrias
Published 2015-10-01

Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation

by Sandra Torres, Estel Solsona-Vilarrasa, Susana Nuñez, Nuria Matías, Naroa Insausti-Urkia, Fernanda Castro, Mireia Casasempere, Gemma Fabriás, Josefina Casas, Carlos Enrich, José C. Fernández-Checa, Carmen Garcia-Ruiz
Published 2021-09-01

A fluorogenic substrate for the detection of lipid amidases in intact cells

by Mireia Casasampere, Johnson Ung, Alejandro Iñáñez, Carine Dufau, Kazuhito Tsuboi, Josefina Casas, Su-Fern Tan, David J. Feith, Nathalie Andrieu-Abadie, Bruno Segui, Thomas P. Loughran, Jr., José Luis Abad, Gemma Fabrias
Published 2024-03-01

Acid ceramidase as a therapeutic target in metastatic prostate cancer[S]

by Luz Camacho, Óscar Meca-Cortés, José Luis Abad, Simón García, Nuria Rubio, Alba Díaz, Toni Celià-Terrassa, Francesca Cingolani, Raquel Bermudo, Pedro L. Fernández, Jerónimo Blanco, Antonio Delgado, Josefina Casas, Gemma Fabriàs, Timothy M. Thomson
Published 2013-05-01

Ovarian Function Modulates the Effects of Long-Chain Polyunsaturated Fatty Acids on the Mouse Cerebral Cortex

by Jose L. Herrera, Lara Ordoñez-Gutierrez, Lara Ordoñez-Gutierrez, Gemma Fabrias, Josefina Casas, Araceli Morales, Guadalberto Hernandez, Nieves G. Acosta, Covadonga Rodriguez, Covadonga Rodriguez, Luis Prieto-Valiente, Luis M. Garcia-Segura, Rafael Alonso, Francisco G. Wandosell, Francisco G. Wandosell
Published 2018-04-01

Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile.

by Paula Mera, Joan Francesc Mir, Gemma Fabriàs, Josefina Casas, Ana S H Costa, Maria Ida Malandrino, José-Antonio Fernández-López, Xavier Remesar, Su Gao, Shigeru Chohnan, Maria Sol Rodríguez-Peña, Harald Petry, Guillermina Asins, Fausto G Hegardt, Laura Herrero, Dolors Serra
Published 2014-01-01