Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells

by Bhanot, Haymanti, Reddy, Mamatha M., Nonami, Atsushi, Weisberg, Ellen L., Bonal, Dennis, Kirschmeier, Paul T., Salgia, Sabrina, Podar, Klaus, Galinsky, Ilene, Chowdary, Tirumala K., Neuberg, Donna, Tonon, Giovanni, Stone, Richard M., Asara, John, Griffin, James D., Sattler, Martin
Published 2016

Targeting MTHFD2 in acute myeloid leukemia

by Pikman, Yana, Puissant, Alexandre, Alexe, Gabriela, Furman, Andrew, Chen, Liying M., Frumm, Stacey M., Ross, Linda, Fenouille, Nina, Bassil, Christopher F., Lewis, Caroline A., Ramos, Azucena, Gould, Joshua, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Clish, Clary B., Kung, Andrew L., Hemann, Michael T., Vander Heiden, Matthew G., Banerji, Versha, Stegmaier, Kimberly
Published 2017

SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia

by Puissant, Alexandre, Alexe, Gabriela, Pikman, Yana, Bassil, Christopher F., Mehta, Swapnil, Du, Jinyan, Kazi, Julhash U., Luciano, Frédéric, Rönnstrand, Lars, Kung, Andrew L., Aster, Jon C., Galinsky, Ilene, Stone, Richard M., DeAngelo, Daniel J., Stegmaier, Kimberly, Fenouille, Nina, Hemann, Michael
Published 2017

Characterization of selective and potent PI3Kδ inhibitor (PI3KD-IN-015) for B-Cell malignances

by Liu, Xiaochuan, Wang, Aoli, Liang, Xiaofei, Chen, Cheng, Liu, Juanjuan, Zhao, Zheng, Wu, Hong, Deng, Yuanxin, Wang, Li, Wang, Beilei, Wu, Jiaxin, Liu, Feiyang, Fernandes, Stacey M., Adamia, Sophia, Stone, Richard M., Galinsky, Ilene A., Brown, Jennifer R., Griffin, James D., Zhang, Shanchun, Loh, Teckpeng, Zhang, Xin, Wang, Wenchao, Weisberg, Ellen L., Liu, Jing, Liu, Qingsong
Published 2016

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity

by van Galen, Peter, Hovestadt, Volker, Wadsworth II, Marc H., Hughes, Travis K., Griffin, Gabriel K., Battaglia, Sofia, Verga, Julia A., Stephansky, Jason, Pastika, Timothy J., Lombardi Story, Jennifer, Pinkus, Geraldine S., Pozdnyakova, Olga, Galinsky, Ilene, Stone, Richard M., Graubert, Timothy A., Shalek, Alex K., Aster, Jon C., Lane, Andrew A., Bernstein, Bradley E.
Published 2020

Selective Akt Inhibitors Synergize with Tyrosine Kinase Inhibitors and Effectively Override Stroma-Associated Cytoprotection of Mutant FLT3-Positive AML Cells

by Weisberg, Ellen, Liu, Qingsong, Zhang, Xin, Nelson, Erik, Sattler, Martin, Liu, Feiyang, Nicolais, Maria, Zhang, Jianming, Mitsiades, Constantine S, Smith, Robert Walsh, Stone, Richard, Galinsky, Ilene, Nonami, Atsushi, Griffin, James D., Gray, Nathanael
Published 2013

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia

by Bassil, Christopher F, Ben-Sahra, Issam, Benajiba, Lina, Alexe, Gabriela, Pikman, Yana, Conway, Amy S, Burgess, Michael R, Li, Qing, Luciano, Frédéric, Auberger, Patrick, Galinsky, Ilene, DeAngelo, Daniel J, Stone, Richard M, Zhang, Yi, Perkins, Archibald S, Shannon, Kevin, Puissant, Alexandre, Stegmaier, Kimberly, Fenouille, Nina, Ramos, Azucena, Hemann, Michael
Published 2018

Simultaneous inhibition of Vps34 kinase would enhance PI3Kδ inhibitor cytotoxicity in the B-cell malignancies

by Liu, Xiaochuan, Wang, Aoli, Liang, Xiaofei, Liu, Juanjuan, Zou, Fengming, Chen, Cheng, Zhao, Zheng, Deng, Yuanxin, Wu, Hong, Qi, Ziping, Wang, Beilei, Wang, Li, Liu, Feiyang, Xu, Yunhe, Wang, Wenchao, Fernandes, Stacey M., Stone, Richard M., Galinsky, Ilene A., Brown, Jennifer R., Loh, Teckpeng, Griffin, James. D., Zhang, Shanchun, Weisberg, Ellen L., Zhang, Xin, Liu, Jing, Liu, Qingsong
Published 2017

Targeting the Creatine Kinase Pathway in EVI1-Positive Acute Myeloid Leukemia

by Fenouille, Nina, Bassil, Christopher, Ben-Sahra, Issam, Benajiba, Lina, Alexe, Gabriela, Ramos, Azucena, Pikman, Yana, Conway, Amy, Burgess, Michael, Li, Qing, Luciano, Frédéric, Auberger, Patrick, Galinsky, Ilene, DeAngelo, Daniel J., Stone, Richard M., Zhang, Yi, Perkins, Archibald, Shannon, Kevin, Hemann, Michael, Puissant, Alexandre
Published 2018

Targeting MTHFD2 in acute myeloid leukemia

by Pikman, Yana, Puissant, Alexandre, Alexe, Gabriela, Furman, Andrew, Chen, Liying M., Frumm, Stacey M., Ross, Linda, Fenouille, Nina, Bassil, Christopher F., Lewis, Caroline, Ramos, Azucena, Gould, Joshua, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Clish, Clary B., Kung, Andrew L., Hemann, Michael, Vander Heiden, Matthew G., Banerji, Versha, Stegmaier, Kimberly
Published 2022

Targeting MTHFD2 in acute myeloid leukemia

by Pikman, Yana, Alexe, Gabriela, Furman, Andrew, Chen, Liying M., Frumm, Stacey M., Ross, Linda, Fenouille, Nina, Bassil, Christopher F., Gould, Joshua, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Clish, Clary B., Kung, Andrew L., Banerji, Versha, Stegmaier, Kimberly, Puissant, Alexandre, Lewis, Caroline, Ramos, Azucena, Hemann, Michael, Vander Heiden, Matthew G.
Published 2017