Eosinophils Are an Endogenous Source of Interleukin-4 during Filarial Infections and Contribute to the Development of an Optimal T Helper 2 Response

by Cécile Guth, Pia Philippa Schumacher, Archena Vijayakumar, Hannah Borgmann, Helene Balles, Marianne Koschel, Frederic Risch, Benjamin Lenz, Achim Hoerauf, Marc P. Hübner, Jesuthas Ajendra
Published 2024-02-01

Repeated sensitization of mice with microfilariae of Litomosoides sigmodontis induces pulmonary eosinophilia in an IL-33-dependent manner.

by Benjamin Lenz, Alexandra Ehrens, Jesuthas Ajendra, Frederic Risch, Joséphine Gal, Anna-Lena Neumann, Julia J Reichwald, Wiebke Strutz, Henry J McSorley, Coralie Martin, Achim Hoerauf, Marc P Hübner
Published 2024-03-01

The efficacy of the benzimidazoles oxfendazole and flubendazole against Litomosoides sigmodontis is dependent on the adaptive and innate immune system

by Frederic Risch, Johanna F. Scheunemann, Julia J. Reichwald, Benjamin Lenz, Alexandra Ehrens, Alexandra Ehrens, Joséphine Gal, Frédéric Fercoq, Marianne Koschel, Martina Fendler, Achim Hoerauf, Achim Hoerauf, Coralie Martin, Marc P. Hübner, Marc P. Hübner
Published 2023-06-01

ILC2s Control Microfilaremia During Litomosoides sigmodontis Infection in Rag2-/- Mice

by Julia J. Reichwald, Frederic Risch, Anna-Lena Neumann, Stefan J. Frohberger, Johanna F. Scheunemann, Benjamin Lenz, Alexandra Ehrens, Alexandra Ehrens, Wiebke Strutz, Beatrix Schumak, Achim Hoerauf, Achim Hoerauf, Marc P. Hübner, Marc P. Hübner
Published 2022-06-01

Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode <i>Litomosoides sigmodontis</i>

by Johanna F. Scheunemann, Frederic Risch, Julia J. Reichwald, Benjamin Lenz, Anna-Lena Neumann, Stephan Garbe, Stefan J. Frohberger, Marianne Koschel, Jesuthas Ajendra, Maximilian Rothe, Eicke Latz, Christoph Coch, Gunther Hartmann, Beatrix Schumak, Achim Hoerauf, Marc P. Hübner
Published 2023-05-01